GPAT Mock Test #1

Important Instructions for GPAT ONLINE mock test takers

Please read the instructions carefully before taking our Online GPAT mock tests

  • This test is intended for registered members only (Click here to register now)
  • DO NOT USE any other programs while attempting the test as it will lead to locking of your attempt and your exam will not be graded.
  • You can attempt the test ONLY ONCE. However, you can review your answers any time after submitting the test any number of times.
  • You cannot stop the test once it is started. The test must be taken continuously for 3 hours. It is advised that the candidates ensure they choose a convenient time to avoid disturbance due to power cuts.
  • The test will be available from 05/01/2014, 10 am onwards.
  • The test can be taken at any time on any day after 05/01/2014 till the actual GPAT 2014 exam.
  • Instant feedback on your performance will be available immediately after the exam. You can see the questions and correct answers along with the answers you marked in the review.
  • All India Ranking will be provided by email. The attempts of the test takers will be taken into account in allotting ranks and percentile. This rank card will be sent to registered email by 11/01/2014.
  • Please note that All India Ranking will be provided only if you attempt the test before results are being mailed.
  • The recommended browser for taking the test is Google Chrome or Firefox
  • Contact us immediately in case you face any technical problems while taking the test.

Test Duration : 3 hours

No of questions is 125

Each question carries 4 marks. Each correct answer fetches you 4 marks while for each incorrect answer 1 mark will be deducted.

All the best !!

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[PPT] Solid Lipid Nanoparticles SLN


Contents of the powerpoint on Solid Lipid Nanoparticles SLN include:
INTRODUCTION
ADVANTAGES AND DISADVANTAGES
COMPARISON OF DIFFERENT COLLOIDAL PARTICLES WITH SLNS
STRUCTURE OF SLN
GENERAL INGREDIENTS
PREPARATION METHODS
CHARACTERIZATION
APPLICATIONS
CONCLUSION
REFERENCES

Scope of PharmD in India

Scope of PharmD in India

SCOPE OF PHARM D IN INDIA

Pharmacists are higher salaried professionals in US and other foreign countries, where pharmacists are allowed to practice clinical pharmacy. They have statutory system in which patient is diagnosed by physicians or doctors (which is their exact responsibility not to prescribe drugs) and then the patient sent ahead to pharmacist with diagnosis report. Pharmacist is allowed to prescribe the patient and normally who charge more than physician. Average salary in USA is 40-50 or more USD per hour in beginning….

In India also the same course called as “Pharm D” is introduced for the academic year 2008- 2009. The Pharmacy Council of India is the apex body controlling the course. Although to date there is not an exact recognition of clinical pharmacy in India but it is sure that one has the greatest & the brightest career in US after clearing the NAPLEX and may be in future in India there will be higher prospectus for the course.

Click here to see B.Pharmacy & M. Pharmacy Projects topics
The basic requirement for pharmacists to be considered for registration is
an undergraduate or postgraduate Pharmacy degree from a recognized university. In most countries this involves a four- or Six year course to attain a Master of Pharmacy (M Pharm). In the United States, students graduating after Jan 1, 2003 must complete a Doctor of Pharmacy degree to become a licensed pharmacist; this requires completion of four years at an accredited college of pharmacy (most students applying for admission into a college of pharmacy already have an undergraduate degree; however, many schools admit students after completion
of 2 years of undergraduate pharmacy prerequisites or directly from high school into a six-year accelerated program). Any person holding a bachelor’s degree in Pharmacy who graduated before this date is grandfathered and can register.
Thus, in USA the legal requirements of becoming a pharmacist include graduating with a Doctor of Pharmacy (Pharm D) degree from an accredited college of pharmacy, serving an internship under a licensed pharmacist, and passing a state (NAPLEX) and law exam. The designation Pharm D is often likened to a PhD degree, however in actuality it is an advanced degree that
became the standard of practice for graduates of pharmacy schools around the turn of the 21st century (2001). The former degree was a Bachelor of Pharmacy and required slightly less schooling and different curriculum. Due to the changes to health care in today’s society and the increasing need for counseling and medication maintenance, pharmacists have taken on a larger role as clinicians. This increase in the need for accessible health care information for consumers has led to great strides in the field of pharmacy. One result of this has been a change in the way
pharmacy schools structure their curriculum as well as an advanced doctorate degree, which further sets the pharmacist apart as a trusted ally in a patient’s health care treatment regimen.

Now you can see Pharmaceutical Companies in Mumbai where you can choose to work.
In fact, pharmacists consistently rank as one of the most trusted professionals in today’s society.This degree requires the completion of at least five years of post-secondary schooling but usually
requires at least 6-8 years at present time, depending on which state you live in and the pharmacy school which you attend. The former degree obtained upon completion of pharmacy school was a Bachelor in Pharmacy or BS and pharmacists with this designation were given the title RPh. In the USA, pharmacists who acquire a Pharm D degree are legally allowed to add the prefix “Dr.” before his / her name. Pharmacy is the health profession that links the health sciences with the chemical sciences and it is charged with ensuring the safe and effective use of pharmaceutical drugs.

Scope of PharmD in India

Scope & Objectives of  PharmD Programme in India:

Objective of Pharm D Programme
1. To provide patient care in cooperation with patients, doctors, and other members of an inter-professional health care team based upon sound therapeutics principles and evidence-based data, taking into account relevant legal, ethical, social cultural, economic and professional issues, emerging technologies, and evolving biomedical,pharmaceutical, social, or behavioral or administrative, and clinical sciences that may impart therapeutic outcomes.

Just check the  Best Pharmacy Schools in USA and links to their Websites
2. To manage and use resources of health care system, in co-operation with patients, doctors and other health care providers and administrative and supportive personnel, to promote health; to provide, assess, and coordinate safe, accurate, and time sensitive medication distribution; and to improve therapeutic outcomes of medication use.
3. To promote health improvement, wellness, and disease prevention in co-operation with patients, communities, at-risk population and other members of an inter-professional team of health care providers.
4. To demonstrate skills in monitoring of the National Health Programmes and schemes, oriented to provide preventive and promotive health care services to the community.
5. To develop leadership qualities to function effectively as a member of health care team organized to deliver the health and family welfare services in existing socio-economic, political and cultural environment.
6. To communicate effectively with patients and the community.

Click here to see Which Countries Offer Best Salaries 4 Pharmacy Graduates? – Pharma Scope

Pharm D Career opportunity

• The prime (No.1) sectors which need the service of Pharm Ds are the pharmaceutical industries. They make new medicines and they need the professionals first than any other sector. Then the second priority comes to the hospitals of pharmacies where it is used or distributed. Production is may be one among ten divisions of an industry where Pharm Ds may not be needed. The numerous and diverse career options available to Pharm D students:

1. Clinical Research

1. Clinical Research : Clinical research is a branch of medical science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease. The term clinical research refers to the entire bibliography of a drug/device/biologic, in fact any test article from its inception in the lab to its introduction to the consumer market and beyond. Once the promising candidate or the molecule is identified in the lab, it is subjected to pre-clinical studies or animal studies where different aspects of the test
(including its safety toxicity if applicable and efficacy, if possible at this early stage) are studied. The focus of clinical research is wide enough to include important items such as data management, medical writing, regulatory consultation, and biostatistics.

Look here to know Top Universities & Colleges of Pharmacy in India

2. Pharmacovigilance

Pharmacovigilance (abbreviated PV or PhV) is the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, particularly long-term and short-term side effects of medicines. Generally speaking, pharmacovigilance is the science of collecting, monitoring, researching, assessing and evaluating information from healthcare providers and patients on the adverse effects of medications, biological products, herbalism and traditional medicines with a view to:
identifying new information about hazards associated with medicines and
2) preventing harm to patients.

3. Research & Development

Research & Development: The phrase research and development refers to the “creative work undertaken on a systematic basis in order to increase the stock of knowledge, including knowledge of man, culture and society, and the use of this stock of knowledge to devise new applications”.

4. Medical Writing

 Medical Writing: Is the activity of producing scientific documentation by a specialized writer. The medical writer typically is not one of the scientists or doctors who performed the research. A medical writer, working with doctors, scientists, and other subject matter experts, creates documents that effectively and clearly describe research results, product use and other medical
information. The medical writer also makes sure the documents comply with regulatory, journal, or other guidelines in terms of content, format and structure.

Don’t miss here  books for GPAT preparation

5. Product Managers:

A product manager investigates, selects, and develops products for an organization, performing the activities of product management.

6. Regulatory affairs:

Regulatory Affairs (RA), also called Government Affairs, is a profession within regulated industries, such as pharmaceuticals and medical devices. Regulatory Affairs professionals usually have responsibility for the following general areas:
Ensuring that their companies comply with all of the regulations and laws pertaining to their business.
Working with federal, state, and local regulatory agencies and personnel on specific issues affecting their business. i.e. working with such agencies as the Food and Drug Administration or European Medicines Agency (pharmaceuticals and medical devices); The Department of Energy; or the Securities and Exchange Commission (banking).
Advising their companies on the regulatory aspects and climate that would affect proposed activities. i.e. describing the “regulatory climate” around issues such as the promotion of prescription drugs and Sarbanes-Oxley compliance.
7. Correspondents & Trainers
8. Top level medical representatives
9. Academics

Never miss List of MNC Pharma companies in INDIA

10. Community Pharmacy:

A community pharmacy is a community-based pharmacy. The main responsibilities of a community pharmacy include appropriate procurement, storage, dispensing, and documentation of medicines.
In compliance with the vision of the community pharmacy section of the International
Pharmaceutical Federation, community pharmacists should
1. be experts in pharmaceutical care, pharmacotherapy, and health promotion.
2. be professional communicators with patients, other healthcare providers, and decision makers.
3. deliver good quality in products, services, and communication.
4. document their actions and make descriptions and publications.
The above mentioned requirement is being fulfilled by the PharmD course.

11.Geriatric Pharmacy:

Geriatrics is a sub-specialty of internal medicine and family medicine
that focuses on health care of elderly people. It aims to promote health by preventing and treating
diseases and disabilities in older adults.

12. Governmental agencies

DRUG INSPECTOR

13. Home Health Care:

Home Care, (also referred to as domiciliary care or social care), is health care or supportive care provided in the patient’s home by healthcare professionals (often referred to as home health care or formal care. Often, the term home health care is used to distinguish non-medical care or custodial care, which is care that is provided by persons who are not nurses, doctors, or other licensed medical personnel, as opposed to home health care that is provided by licensed personnel.

14. Hospital Pharmacy:

A hospital pharmacy is concerned with pharmacy service to all types of hospital and differs considerably from a community pharmacy. Some pharmacists in hospital pharmacies may have more complex clinical medication management issues whereas pharmacists in community pharmacies often have more complex business and customer relations issues. Because of the complexity of the medication use system, many pharmacists practicing in hospitals gain more education and training after pharmacy school through a pharmacy practice
residency and sometimes followed by another residency in a specific area.

15. Managed Care:

The term managed care is used in the United States to describe a variety of techniques intended to reduce the cost of providing health benefits and improve the quality of care (“managed care techniques”) for organizations that use those techniques or provide them as services to other organizations (“managed care organization” or “MCO”), or to describe systems of financing and delivering health care to enrollees organized around managed care techniques
and concepts (“managed care delivery systems”). According to the United States National Library of Medicine, the term “managed care” encompasses programs:
…intended to reduce unnecessary health care costs through a variety of mechanisms, including:
economic incentives for physicians and patients to select less costly forms of care; programs for reviewing the medical necessity of specific services; increased beneficiary cost sharing; controls on inpatient admissions and lengths of stay; the establishment of cost-sharing incentives for outpatient surgery; selective contracting with health care providers; and the intensive
management of high-cost health care cases.

16. Pharmacoeconomics:

Refers to the scientific discipline that compares the value of one pharmaceutical drug or drug therapy to another. It is a sub-discipline of Health economics. A pharmacoeconomic study evaluates the cost (expressed in monetary terms) and effects (expressed in terms of monetary value, efficacy or enhanced quality of life) of a pharmaceutical product. We can distinguish several types of pharmacoeconomic evaluation: cost-minimization analysis, cost-benefit analysis, cost-effectiveness analysis and cost-utility analysis. Pharmacoeconomic studies serve to guide optimal healthcare resource allocation, in a standardized and scientifically grounded manner. One important consideration in a pharmacoeconomic evaluation is to decide the perspective from which the analysis should be conducted (such as institutional or societal).
17. Any more opportunities that can be explored…….

courtesy: Venkat Ch

Advantages of writing / attempting GPAT 2014

  • It is a national level entrance test which will facilitate admission into postgraduate courses valid all over India.
  • Qualifying in GPAT is a necessary condition for appearing to NIPER-JEE exam which is also an entrance exam for admission into various postgraduate courses in seven National Institute of Pharmaceutical Education and Research (NIPERs) across India (For more information on various NIPERs, click here).
  • A candidate will be paid scholarship of Rs. 8,000/- per month by AICTE (AICTE-Postgraduate scholarship) if he/she is admitted into any postgraduate course through valid GPAT score and proper counseling procedure.
  • CSIR has now recognized GPAT for admission into PhD. Some CSIR institutions through out India are considering GPAT qualified candidates. A GPAT qualified candidate interested in research can approach any a scientist working the area of his/her interests and apply during admission process. Alternatively, AcSIR will release a notification twice in a year via all CSIR institutes to which candidates can apply.

General note:

  • Since GPAT is a national level aptitude test, the score is an index of the candidate’s capability. Therefore, students who wish to pursue their higher education outside India are also suggested to write the GPAT.  Qualifying in GPAT is a good credential to have and a top score will further strengthen your curriculum vitae. Though GPAT qualification is not a necessary condition for admission to foreign schools, many academicians believe that a good score will speak on the candidate’s grip over various subjects in Pharmaceutical sciences. Thereby facilitating the candidate in getting into a good university.
  • For students willing to study in India, it is not only a prerequisite for admission into PG course but even after one completes the courses; it will be helpful for PhD admission into various institutions including NIPERs. For appearing to NIPER-JEE (PhD Entrance test, it is necessary to have a GPAT qualification). All the universities consider qualification in GPAT as a meritorious credential during some point of PhD admission process.
  • GPAT qualified candidate may also have an advantage during various interviews for jobs in industry/ academia.

 

Have more doubts? Read FAQ here

For more information on GPAT-2014 and to apply online click here.

[FAQ] All about GPAT 2014

GPAT 2014
GPAT 2014
GPAT 2014

1.Q) GPAT 2014. What is it all about?

Remember the entrance exam you wrote after 12th? You missed the rank and instead of being a doctor landed up in B.Pharm. Graduate Pharmacy Aptitude Test, GPAT, is an entrance exam of same importance for your career after B.Pharmacy

2.Q) Who should write this exam?

All pharmacy graduates should write this exam. It is essential that one must QUALIFY this exam atleast once. Apart from serving as an entrance exam for M.Pharmacy admission into a top college it also helps u to get a scholarship

Mpharm Admission into a good college
Scholarship in M.Pharm (Rs 8000*/month, a total of Rs.1.92 lakh for entire M.Pharm course)
Admission into NIPER, the apex pharmacy institutes of India needs GPAT qualified to appear its own entrance exam!
Ph.D Many Universities consider GPAT as a must for Ph.D admissions. At sometimes a GPAT qualified candidate will be preferred to a non GPAT person
In Some universities, Ph.D entrance test may be waived off if you qualify GPAT

 

3.Q) I am in B.Pharm 2nd year. As per the notification I am ineligible for GPAT 2014. Isnt it?

Officially you are NOT eligible for GPAT exam. That should not prevent you from writing the exam. Most students write this exam in their B.Pharm 3rd year so as to get a feel before they give the exam in final year. However the score (Qualified/ Not Qualified) might not be useful to you. Attempt it if only want to get a feel of the exam.

4.Q) I want to fly abroad. MS in US. I don’t care about GPAT. GRE’s my savior.

Well that’s a good decision of going abroad. We respect it. But it is suggested that you give an attempt at the GPAT also. No need to devote time away from GRE preparation but just attempt GPAT. Who knows you may want to pursue your Ph.D in India after completion of your MS.

And remember qualifying GPAT is easiest when you are in B.Pharm compared to after M.Pharm or M.S. Trust me!

5.Q) GPAT exam is online. Online is tough right?

Wrong. Based on my personal experience online exams are much easier than the offline exams. In an online exam you get more time because you don’t have to waste time on bubbling circles on OMR paper.

If you are able to surf the internet and use the mouse, you have the skills required to write the GPAT exam online. However practice will help. You should have given atleast 3-5 mock tests online (not the paper based tests of your coaching test). This will help you understand the structure of online exam.

Pharmawiki is planning to conduct Model Gpat exam in the month of December. Click here to know the details

Future articles coming up on GPAT 2014

  1. Choosing the ideal date and session for GPAT exam
  2. Coping with the online GPAT exam. Tips and best practices

Vacancies in Mylan

B. Pharmacy & M. Pharmacy Jobs For Freshers & Experienced In Hyderabad Bangalore Mumbai

Vacancies for Fresh Graduate in pharmacy as Chemist- Production-Unit-3 in Mylan

Post: Chemist – Production-Unit-3-JDM

 Job Description: 

At Mylan, each person has the ability to make a difference. From the providers who sell and market our products to the producers who develop and manufacture them and finally to our business partners who support the providers and producers, we all have a mission critical role. Here’s how this role will help:

  • Take charge of the operations from the previous Chemist/ Officer; Verifyand charge the raw material quantities as per the BPR; Execute the production process as per the BPR and highlight any issues from shop floor to shift incharge for guidance and resolution; Complete the batch production record and other documents online; Maintain the shop floor area during the shift as per cGMP norms (housekeeping, hygiene etc.) with special focus on handling of final API
  • For FDF: Co-ordinate to resolve breakdowns during the shift with maintenance department; Use proper PPE and adhere to all safety norms during the shift; Report any non compliance/ incidents during the shift; Perform in-process test as per the defined frequency

Qualifications

API: Graduate in Science
FDF: Graduate in Pharmacy
API: Minimum of  2 years of experience in API manufacturing / chemical industry
FDF: Fresher/ 1 year of experience with exposure to (formulation manufacturing preferred)
Knowledge of production technologies and quality systems, regulatory and GMP guidelines, EHS requirements

Additional Information:
Experience: 1-2 year
Location: Andhra Pradesh-Hyderabad
Industry Type: Pharma/Biotech/Clinical Research
Functional Area: Production
End Date: 30th Nov, 2013

https://mylan.taleo.net/careersection/2/jobdetail.ftl?job=46282&lang=en&sns_id=

Jobs in Thomson Reuters both in Chennai and Hyderabad

B. Pharmacy & M. Pharmacy Jobs For Freshers & Experienced In Hyderabad Bangalore Mumbai

Jobs in Thomson Reuters both in Chennai and Hyderabad:

Associate Research Analyst / Research Analyst:

Knowledge of organic and stereochemistry chemistry to comprehend and interpret source material, and depict structures accurately, Ability to work in a high-pressure, production oriented environment while maintaining quality and quantity, Decision-making ability within established editorial guidelines and practices. Education: Master’s Degree in Chemistry, preferably Organic with good knowledge of Organic and Stereochemistry,

Chennai:

Date: Wednesday, 13th November 2013
Time: 4:30 PM to 5:00 PM
Venue: Thomson Reuters – Acroplis(5th,10th & 11th Floors), #148, Dr. Radha Krishna Salai Mylapore – Chennai
Contact person: Sridharan Sathyabama

Hydearbad:

Date: Saturday, 9th November 2013
Time: 9:00 AM to 10:00 AM
Venue: Thomson Reuters – Divyashree solitaire building, 5th floor cafeteria, Hitech City, Madhapur – Hyderabad
Contact person: Bharathi

Discovery and Development of Natural Products as lead compounds

Approaches to Discovery and Development of Natural Products as lead compounds 

There are multiple hit identification strategies, and new drugs come from many sources, both rational and brute force. The exploitation of drug prototypes has been reviewed extensively. Some have argued that starting with an old drug is the best way to find a new drug. This has been called selective optimization of side activities (SOSA). Thus, one starts with a diverse collection of marketed drugs in order to find and then optimize hits against new pharmacological targets. Because the starting points have already proved useful in man, the hits are guaranteed to be drug-like. A number of successful SOSA examples have been reported starting from sulfonamides, calcium channel blockers, beta blockers, antidepressants, neuroleptics, and so on. Despite the power of combinatorial chemistry and HTS, natural products still provide unique structural diversity. Natural molecules have intrinsic advantages, of course, having evolved alongside biological systems. Mother Nature had eons of a head start versus medicinal chemists. Thus, it might have been predictable that a large percentage, almost 30%, of the NCEs approved by the FDA between 1981 and 2002 were natural products or compounds derived from natural products. Natural products (or derivatives) with important therapeutic uses today include the antibiotic vancomycin, the anticholinergic scopolamine, and the opiate morphine, to name just a few.

 However, in recent years, natural products have gone out of favor in some circles, in part because they have been less compatible with other new technologies, such as HTS.

New drugs come from many sources including:

* Focused synthesis of new chemical structures

* Modification of old drugs (new analogs)

* New uses for old drugs (repositioning or repurposing)

* Endogenous substances found in humans;

* Natural products from non-human sources; and

* Random screening.

Though the field of combinatorial chemistry is still evolving, it has already made a mark on the industry.

Drug Discovery

                                                                                                     Hit identification strategies.

 The most commonly applied hit identification strategies today range from knowledge based approaches, which use literature- and patent-derived molecular entities, endogenous ligands or biostructural information, to the purely serendipity-based ‘brute force’ methods such as combinatorial chemistry and high-throughput screening.

Serendipity, Combinatorial chemistry and HTS play a major role in identification of lead molecules from natural products

In brief Drugs from Natural Sources can be identified by the following processes

  1. Serendipity
  2. random collection and screening of material
  3. Exploitation of ethnopharmacological knowledge.
  4. HTS – High Thoroughput Screening
  5. Combinatorial chemistry.

 

 

Regulatory Affairs

B.Sc, M.Pharm, M.Sc as Officer / Executive – Regulatory Affairs – API @ Sun Pharma

 Sun Pharma ranks amongst India’s largest pharma companies We’have  built a reputation for speciality therapy leadership and faster- than-industry growth over the last 30 years. From a modest beginning with five people, our team today exceeds 13,000 and growing, put manufacturing base now spans 25 sites across the world. With a market cap of over $ 16 billion, we’re also India’s most valued pharma brand. To keep pace with our growth plans, we require for our Formulation manufacturing plant at Halo! (Near Baroda):

 

Post: Officer / Executive – Regulatory Affairs – API

 

Job description
1. Preparation and Execution of Drug Master files of API in CTD and ECTD format, independently in coordination with plant people.
2. Checking and reviewing of documents required for DMF filing received from plant for its thoroughness and getting corrections done from plant, independently.
3. Handling to DMF deficiencies Preparation of action plan and deficiency responses Timely Response of DMF deficiencies in coordination from R&D, Plant , ADD
4. Annual updates of DMF and renewal applications for CEP .
5. Completion of QA and ISO questionnaire received from customers in coordination with plants.
6. Helping API plants for the preparation of audits from Regulatory Agencies, in case required.
7. Moving to API locations for checking and collection of documents as and when required.

 

Desired Skills and Experience


Qualification – Bsc, Msc, M. pharma

Experience – 4 to 9 years of experience in API Regulatory Affairs

Additional Information:

Qualification: Bsc, Msc, Mpharm

Experience: 4-9 Year

Industry Type: Pharma/Biotech/Clinical Research

Functional Area: DRA

End Date: 16th Nov, 2013

Apply through their website

walk-in Interview for Pharmacovigilance_Fresher

walk-in Interview for Pharmacovigilance_Fresher

Date: 05 & 06 November 2013; Time: 10:00 AM to 1:00 PM (Registration closes at 1:00 PM)

Location:
@Banglore:
Synowledge PV Services India Pvt. Ltd.,
# 120/A, Elephant Rock Road,
Jayanagar 3rd Block,
Bangalore 560011.
Landmark: Opp RR Gold Palace
Contact Person: Vidya

@Mysore:
Synowledge PV Services India Pvt. Ltd.,
Jadoli Campus, No. 120P-122P,
Belagola Industrial Area,
KRS Road, Near GRS Fantasy Park,
Mysore 570016
Contact Person: Sania

E.Q: B.Pharma, BDS, B.Sc – Nursing, M.Pharma

Courtesy by Srini Vasan