Contents of the powerpoint on Cytochrome p450 metabolism include:
INTRODUCTION
CYTOCHROME P450 NOMENCLATURE
COMPONENTS OF CYP450
MECHANISM – CATALYTIC CYCLE
FAMILY OF CYTOCHROME P450 IN VARIOUS SPECIES
GENETIC POLYMORPHISM
SPECTRUM OF CONSEQUENCES OF DRUG METABOLISM
PHASES OF DRUG METABOLISM
CONCLUSION
REFERENCES
The cytochrome p450 enzymes (cyps) are a diverse super family of enzymes which taken together,are capable of metabolising wide variety of endogenous and xenobiotic substances including drug molecules.
Cytochrome P450 enzymes (hemoproteins) play an important role in the intra-cellular metabolism.
Cyps have been extensively studied in animals (rats,mice dogs and to less extent in zebra fish), in bacteria ,in fungi,in insects, in plants and in humans, (prokaryotic and Eucaryotic).
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