Contents of the powerpoint on Volume Of Distribution include:
Objective
Definition
Protein binding of drugs
Tissue binding of drugs
Factors affecting volume of distribution
Steady state volume of distribution
Relationship between clearance & VD & t1/2
Significance
Conclusion
References
To understand and describe the processes by which drugs are distributed throughout the body
To differentiate between apparent volume of distribution & true physiological volume
To understand the effect of protein and tissue binding on volume of drug distribution.
The volume of distribution (VD) , also known as apparent volume of distribution, is a pharmacological term used to quantify the distribution of a medication between plasma and the rest of the body after oral or parenteral dosing.
It is defined as the volume in which the amount of drug would need to be uniformly distributed to produce the observed blood concentration.
The volume of distribution is a hypothetical volume of fluid into which a drug is distributed, it’s a useful in predicting amount of drug in the body.
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