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Pharmacology MCQ for Anti Cancer Chemotherapy Drugs
ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER
All of the following antiviral drugs are the analogs of nucleosides, EXCEPT:
a) Acyclovir
b) Zidovudine
c) Saquinavir
d) Didanozine
Tick the drug, a derivative of adamantane:
a) Didanozine
b) Rimantadine
c) Gancyclovir
d) Foscarnet
Tick the drug, a derivative of pyrophosphate:
a) Foscarnet
b) Zidovudine
c) Vidarabine
d) Acyclovir
Tick the drug, inhibiting viral DNA synthesis:
a) Interferon
b) Saquinavir
c) Amantadine
d) Acyclovir
Tick the drug, inhibiting uncoating of the viral RNA:
a) Vidarabine
b) Rimantadine
c) Acyclovir
d) Didanozine
Tick the drug, inhibiting viral reverse transcriptase:
a) Zidovudine
b) Vidarabine
c) Rimantadine
d) Gancyclovir
Tick the drug, inhibiting viral proteases:
a) Rimantadine
b) Acyclovir
c) Saquinavir
d) Zalcitabine
Tick the drug of choice for herpes and cytomegalovirus infection treatment:
a) Saquinavir
b) Interferon alfa
c) Didanozine
d) Acyclovir
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Tick the drug which belongs to nonnucleoside reverse transcriptase inhibitors:
a) Zidovudine
b) Vidarabine
c) Nevirapine
d) Gancyclovir
All of the following antiviral drugs are antiretroviral agents, EXCEPT:
a) Acyclovir
b) Zidovudine
c) Zalcitabine
d) Didanozine
Tick the drug used for influenza A prevention:
a) Acyclovir
b) Rimantadine
c) Saquinavir
d) Foscarnet
Tick the drug used for HIV infection treatment, a derivative of nucleosides:
a) Acyclovir
b) Zidovudine
c) Gancyclovir
d) Trifluridine
Tick the antiviral drug which belongs to endogenous proteins:
a) Amantadine
b) Saquinavir
c) Interferon alfa
d) Pencyclovir
Tick the drug which belongs to nucleoside reverse transcriptase inhibitors:
a) Didanosine
b) Gancyclovir
c) Nevirapine
d) Vidarabine
All of the following antiviral drugs are anti-influenza agents, EXCEPT:
a) Acyclovir
b) Amantadine
c) Interferons
d) Rimantadine
Tick the unwanted effects of zidovudine:
a) Hallucinations, dizziness
b) Anemia, neutropenia, nausea, insomnia
c) Hypertension, vomiting
d) Peripheral neuropathy
Tick the unwanted effects of intravenous acyclovir infusion:
a) Renal insufficiency, tremors, delerium
b) Rash, diarrhea, nausea
c) Neuropathy, abdominal pain
d) Anemia, neutropenia, nausea, insomnia
Tick the drug that can induce peripheral neuropathy and oral ulceration:
a) Acyclovire
b) Zalcitabine
c) Zidovudine
d) Saquinavir
Tick the unwanted effects of didanozine:
a) Hallucinations, dizziness, insomnia
b) Anemia, neutropenia, nausea
c) Hypertension, vomiting, diarrhea
d) Peripheral neuropathy, pancreatitis, diarrhea, hyperuricemia
Tick the unwanted effects of indinavir:
a) Hypotension, vomiting, dizziness
b) Nephrolithiasis, nausea, hepatotoxicity
c) Peripheral neuropathy, pancreatitis, hyperuricemia
d) Anemia, neutropenia, nausea
Tick the drug that can induce nausea, diarrhea, abdominal pain and rhinitis:
137
a) Acyclovire
b) Zalcitabine
c) Zidovudine
d) Saquinavir
All of the following effects are disadvantages of anticancer drugs, EXCEPT:
a) Low selectivity to cancer cells
b) Depression of bone marrow
c) Depression of angiogenesis
d) Depression of immune system
Rational combination of anticancer drugs is used to:
a) Provide synergism resulting from the use of anticancer drugs with different mechanisms combination
b) Provide synergism resulting from the use of anticancer drugs with the same mechanisms combination
c) Provide stimulation of immune system
d) Provide stimulation of cell proliferation
Tick the anticancer alkylating drug, a derivative of chloroethylamine:
a) Methotrexate
b) Cisplatin
c) Cyclophosphamide
d) Carmustine
Tick the anticancer alkylating drug, a derivative of ethylenimine:
a) Mercaptopurine
b) Thiotepa
c) Chlorambucil
d) Procarbazine
Tick the group of hormonal drugs used for cancer treatment:
a) Mineralocorticoids and glucocorticoids
b) Glucocorticoids and gonadal hormones
c) Gonadal hormones and somatotropin
d) Insulin
Tick the anticancer alkylating drug, a derivative of alkylsulfonate:
a) Fluorouracil
b) Carboplatin
c) Vinblastine
d) Busulfan
Tick the anticancer drug of plant origin:
a) Dactinomycin
b) Vincristine
c) Methotrexate
d) Procarbazine
Action mechanism of alkylating agents is:
a) Producing carbonium ions altering protein structure
b) Producing carbonium ions altering DNA structure
c) Structural antagonism against purine and pyrimidine
d) Inhibition of DNA-dependent RNA synthesis
Tick the anticancer drug, a pyrimidine antagonist:
a) Fluorouracil
b) Mercaptopurine
c) Thioguanine
d) Methotrexate
Methotrexate is:
a) A purine antagonist
b) A folic acid antagonist
c) An antibiotic
d) An alkylating agent
Tick the antibiotic for cancer chemotherapy:
a) Cytarabine
b) Doxorubicin
c) Gentamycin
d) Etoposide
Fluorouracil belongs to:
a) Antibiotics
b) Antimetabolites
c) Plant alkaloids
d) Bone marrow growth factor
Tick the action mechanism of anticancer drugs belonging to plant alkaloids:
a) Inhibition of DNA-dependent RNA synthesis
b) Cross-linking of DNA
c) Mitotic arrest at a metaphase
d) Nonselective inhibition of aromatases
ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER
General contraindications for anticancer drugs are:
a) Depression of bone marrow
b) Acute infections
c) Severe hepatic and/or renal insufficiency
d) All of the above
Action mechanism of methotrexate is:
a) Inhibition of dihydrofolate reductase
b) Activation of cell differentiation
c) Catabolic depletion of serum asparagine
d) All of the above
Tick the anticancer drug belonging to inorganic metal complexes:
a) Dacarbazine
b) Cisplatin
c) Methotrexate
d) Vincristine
Tick the indication for estrogens in oncological practice:
a) Leukemia
b) Cancer of prostate
c) Endometrial cancer
d) Brain tumors
Enzyme drug used for acute leukemia treatment:
a) Dihydrofolate reductase
b) Asparaginase
c) Aromatase
d) DNA gyrase
All of the following drugs are derivatives of nitrosoureas, EXCEPT:
a) Carmustine
b) Vincristine
c) Lomustine
d) Semustine
Tick the group of drugs used as subsidiary medicines in cancer treatment:
a) Cytoprotectors
b) Bone marrow growth factors
c) Antimetastatic agents
d) All of the above
Tick the estrogen inhibitor:
a) Leuprolide
b) Tamoxifen
c) Flutamide
d) Anastrozole
Tick the antiandrogen drug:
a) Flutamide
b) Aminoglutethimide
c) Tamoxifen
d) Testosterone
Tick the drug belonging to aromatase inhibitors:
a) Octreotide
b) Anastrozole
c) Flutamide
d) Tamoxifen
Tick the drug belonging to gonadotropin-releasing hormone agonists:
a) Leuprolide
b) Tamoxifen
c) Flutamide
d) Anastrozole
Pharmacology MCQ for Anti Cancer Chemotherapy Drugs
Pharmacology MCQ for Anti Cancer Chemotherapy Drugs
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