PPT PDF – HPLC – Principle Types Modes Advantages- Limitation

hplc instrumentation

If you want to know completely about High-Performance Liquid Chromatography HPLC you are at the right place.In this article you can find from the basics of chromatography along with the Principle of High-Performance Liquid Chromatography and parameters that are used as a standard for a particular compound in High-Performance Liquid Chromatography (HPLC).Types of High-Performance Liquid Chromatography (HPLC). Instrumentation and applications uses of High-Performance Liquid Chromatography (HPLC)are provided here. You can download the PPT AND PDF on HPLC in the following paragraphs.

What is chromatography ?

Chromatography is a separation technique that uses the size, shape, chemical properties or charge of molecules in a sample to separate the sample into its constituent components.
Chromatography is a physical method of separation in which the components to be separated are, distributed two phases, one of which is stationary phase while the other is mobile phase, moves in a definite direction.

Chromatography Principle

Chromatography is based on the principle where molecules in mixture applied onto the surface or into the solid, and fluid stationary phase (stable phase) is separating from each other while moving with the aid of a mobile phase. e factors effective on this separation process include molecular characteristics related to adsorption (liquid-solid), partition (liquid-solid), and affinity or differences among their molecular weights. Because of these differences, some components of the mixture stay longer in the stationary phase, and they move slowly in the chromatography system, while others pass rapidly into mobile phase, and leave the system faster

Why HPLC?

  • HPLC came about because not all compounds can be vaporized and analyzed on a GC
  • Separation of a wider range of compounds — high MW, polar, and ionic compounds
  • Highly efficient separations achieved in HPLC due to interactions of both m.p. and s.p. with the components of a mixture.
  • Improved separation within a much shorter time

 What is High-performance liquid chromatography (HPLC)?

HPLC represents an automated system for the separation of compounds in mixture using a liquid mobile phase, which is passed across the stationary phase under high pressure in order to speed up the operation.
The effluent of the column is monitored by special detectors and the signals for the eluted components are recorded in a special recorder which amplifies such signals and record them as peaks similar to those obtained in gas chromatography.

 

HPLC PRINCIPLE

HPLC works on the principle of Affinity chromatography. The solution of the sample is injected into a column of a porous material (stationary phase) and a liquid (mobile phase) is pumped at high pressure through the column. The mixture on travelling through the stationary phase splits into its constituents and the component with high affinity for stationary phase travels late whereas one with less affinity elutes fast. This is also based partition coefficient of the material.

To make you understand, in simple terms HPLC follows the principle of separation in both normal phase mode and reverse phase mode is adsorption. When a mixture of components are introduced into a HPLC column, they travel according to their relative affinities towards the stationary phase. The component which has more affinity towards the adsorbent, travels slower. The component which has less affinity towards the stationary phase travels faster. Since no 2 components have the same affinity towards the stationary phase, the components are separated.

TYPES OF HPLC TECHNIQUES:

A. Based on modes of chromatography
1. Normal phase mode
2.Reverse phase mode
B. Based on principle of separation
1. Adsorption chromatography
2. Ion exchange chromatography
3. Ion pair chromatography
4.Size exclusion(or)Gel permeation chromatography
5. Affinity chromatography
6. Chiral phase chromatography
C. Based on elution technique
1. Isocratic separation
2. Gradient separation
D. Based on the scale of operation
1. Analytical HPLC
2. Preparative HPLC
E. Based on the type of analysis
1. Qualitative analysis
2. Quantitative analysis

HPLC INSTRUMENTATON  BASIC INFORMATION:

1. Solvent delivery system
2. Pumps
3. Sample injection system
4. Column
5. Detectors
6. Recorders and Integrators

Applications of High-Performance Liquid Chromatography (HPLC)

  • Pharmaceutical applications of HPLC are Tablet dissolution study of pharmaceutical dosages form, Shelf-life determinations of pharmaceutical products,  Identification of active ingredients of dosage forms, Pharmaceutical quality control applications,  Detection of phenolic compounds in Drinking Water, Identification of compounds in sediment samples, Bio-monitoring of pollutant, Quantification of the drug in biological samples. • Identification of anabolic steroids in serum, urine, sweat, and hair,Determination of cocaine and metabolites in blood Clinical Quantification of ions in human urine Analysis of antibiotics in blood plasma, Estimation of bilirubin and biliverdin in blood plasma in case of hepatic disorders,Detection of endogenous neuropeptides in extracellular fluids of brain.
  • Other applications include testing the quality of soft drink and drinking water, Analysis of beer, Sugar analysis in fruit juices, Analysis of polycyclic compounds in vegetables,Trace analysis of military high explosives in agricultural crops.
  • Chemical Separations
  • Purification

.

HPLC USES

1. Separations fast and efficient (high resolution power)
2. Continuous monitoring of the column effluent
3. It can be applied to the separation and analysis of very complex mixtures
4. Accurate quantitative measurements.
5. Repetitive and reproducible analysis using the same column.
6. Adsorption, partition, ion exchange and exclusion column separations are excellently made
7. HPLC is more versatile than GLC in some respects, because it has the advantage of not being restricted to volatile and thermally stable solute and the choice of mobile and stationary phases is much wider in HPLC
8. Both aqueous and non aqueous samples can be analyzed with little or no sample pretreatment
9. A variety of solvents and column packings are available, providing a high degree of selectivity for specific analyses.
10. It provides a means for determination of multiple components in a single analysis.

Advantages of High-Performance Liquid Chromatography (HPLC)

  • By using this High-Performance Liquid Chromatography (HPLC) technique it is possible to perform structural, and functional analysis, and purification of many molecules within a short time.
  • This technique yields perfect results in the separation, and identification of amino acids, carbohydrates, lipids, nucleic acids, proteins, steroids, and other biologically active molecules
  • In HPLC, mobile phase passes throuıgh columns under 10–400 atmospheric pressure, and with a high (0.1–5 cm//sec) flow rate.
  • In this technique, use of small particles,and application of high pressure on the rate of solvent flow increases separation power, of HPLC and the analysis is completed within a short time

PARAMETERS USED IN HPLC:

1.Retention time
2.Retention volume
3.Separation factor
4. Resolution
5. Height Equivalent to a Theoretical Plate (HETP)
6. Efficiency
7. Asymmetry factor

What are hplc detectors

The work of detector is to detect and give the information to the recorder which shows it in a form of a chromatogram. Every compounds has its own properties which is not completely the same with one another, thus this arises a need to have different detectors for different compounds. Before beginning the separation by HPLC it is thus very important to study about the nature of the compound and select the detector accordingly. The selection of wrong detector misguides our journey of separation and quantification.

Types of hplc detectors

1. Refractive index detectors
2. U.V detectors
3. Fluorescence detectors
4. Electro chemical detectors
5. Evaporative light scattering detectors
6. IR detectors
7. Photo diode array detector:

what are most common hplc detector

Detectors used depends upon the property of the compounds to be separated.  Detectors  are elemental detectors (atomic absorption/emission, inductively coupled plasma–mass spectrometry and microwave-induced plasma); optical detectors (UV/visible, IR/Raman, optical activity, evaporative light scattering and refractive index); luminescent detectors (fluorescence/phosphorescence, chemiluminescence/bioluminescence); electrochemical detectors (potentiometry, novel material/modified electrodes, array electrodes and pulsed
and oscillometric techniques); mass spectrometric detectors (time-of-flight/MALDI, Fourier transform ion cyclotron resonance mass spectrometry, electrospray/thermospray, atmospheric pressure ionization and particle beam); and other detection systems (nuclear magnetic resonance, radioactivity detectors, surface plasmon resonance)

MODES  OF HPLC

HPLC Modes
• Normal-phase (NPC)
– Separation based on adsorption of the analyte onto a polar surface (silica)
• Reversed-phase (RPC)
– Separation based on analytes’ partition coefficients between the mobile phase and the bonded  stationary phase
• Ion-exchange (IEC)
– Separation based on ion-exchanging with the counter-ions and ionic interaction with the bonded ionic group
• Size-exclusion (SEC orGFC)
– Separation based on analyte’s molecular size and  sieving action of the column packing

Limitations  of  HPLC

  • Lack of a Universal Detector.   The lack of a universal detector is often mentioned, although the UV–vis detector comes close to one for chromophoric compounds. Refractive index detection fits the bill, but suffers from low sensitivity and incompatibility with gradient elution. Evaporative light scattering detection (ELSD) was a contender, but was surpassed by charged aerosol detection (CAD). CAD uses a nebulizer with corona discharge detection and has better sensitivity (low ng) and ease-of-use than ELSD
  • Less Separation Efficiency than Capillary Gas Chromatography Conventional.  HPLC has a practi-cal peak capacity (Pc) of ~200 using columns with ~20,000 plates under gradient conditions — not particularly effective for very complex samples
  • Relatively More Difficult for Novices  The bewildering number of HPLC modules, columns, mobile phases, and operating parameters renders HPLC difficult for the novice.
  • Still Arduous, Particularly for Regulated Testing  HPLC is versatile, quantitative, sensi-tive, and extremely precise. It can also be time-consuming and arduous, particularly for regulated analysis under good manufacturing practices (GMP).

Conclusion

HPLC is a complex technique because of its myriad combinations of modules, columns or mobile phases, and operating parameters. Initially chromatographic techniques were used to separate substances based on their color as was the case with herbal pigments. With time its application area was extended considerably. Nowadays, chromatography is accepted as an extremely sensitive, and effective separation method.
HPLC technique which has many superior features including especially its higher sensitivity, rapid turnover rate, its use as a quantitative method, can purify amino acids, proteins, nucleic acids, hydrocarbons, carbohydrates, drugs, antibiotics, and steroids

hplc ppthplc ppt office b pharm m pharm office b pharm m pharm

hplc ppt – complete information on high performance liquid chromatography office b pharm m pharm

References

  • Handbook of Pharmaceutical Analysis by HPLC, S. A huja and M.W. Dong , Ed s. (Elsevier/Academic Press, 2005).
  • HPLC for Pharma ceutical Scientists, Y.V. Kazakevich and R. LoBrutto, Eds. (Wiley, Hoboken, New Jersey, 2007).
  • C.F. Poole, Essence of Chromatography (Elsevier Science, Amsterdam, The Netherlands, 2002).
  • Chromatog raphy: A Scien ce of Discovery, R.L. Wixom and C.L . Gehrke, Eds. (Wiley, Hoboken, New Jersey, 2010).
  • UHPLC in Life Scie nce s, D. Guillarme, J-L Veuthey, and R.M. Smith, Eds. (Royal Society of Chemistry, Cambridge, United Kingdom, 2012).
  • M. Swartz, M. Emmanuel, A. Awad, and D. Hartley, “Advances in HPLC Systems Technology” supplement to LCGC North Am. 27(4), 40–48 (2009).
  • Mass Spectrometry for Drug Discovery and Drug Development, W.A. Korfmacher, Ed.(Wiley, Hoboken, New Jersey, 2013).
  • J.E. MacNair, K.C. Lewis, and J.W. Jorgenson, Anal. Chem. 69, 983–989 (1997).
  • M.W. Dong, LCGC North Am. 25(7), 656– 666 (2007).
  • N. Wu a nd A.M. Clausen, J. Sep. Sci. 30,1167–1182 (2007).
  • D. Gui ll arme and M.W. Dong , Amer. Pharm. Rev., (2013) submitted.
  • M.W. Dong , D. Guillarme, S. Fekete, R. Rangelova, J. Richa rds, D. Prudhomme, and N.P. Chetwyn, J. Chromatogr. A. submitted.
  • L. Sannes, “Commercia lizing Biomarkers in Therapeutic and Diagnostic Application– Overview,” Insight Pharma Report

Important Questions on  HPLC

Questions
1. Contrast the advantages and disadvantages of thin layer chromatography
(TLC) versus modern HPLC.
2. What does HPLC stand for?
3. What are the advantages of dual reciprocating pumps have over syringe
pumps?
4. How much does a basic HPLC system cost?
5. What are the sub-categories of liquid chromatography?
6. What is the difference between normal phase HPLC and reverse phase
HPLC? Which is most commonly used today?
7. What chemical factors determine if a chemical will be analyzed in a GC or LC?
8. Can moderately volatile, thermally stable chemical be analyzed on an LC?
9. Why do we filter analyte solutions before injection into an HPLC?
10. Draw a basic HPLC system and label all of the components.
11. Why are pressurized gases used in HPLC?
12. What two preparatory steps must be taken before a solvent can be used as an HPLC mobile phase?
In general, what is the maximum pressure limit of standard HPLC systems?
13. What is the purpose of the proportioning valve? How does this reduce the cost of an HPLC?
14. What is the difference in isocratic and gradient programming? Why is gradient programming sometimes necessary?
15. Why are dual piston pumps preferred over single piston pumps?
16. What is the purpose of a pulse damper?
17. Why are six-port valves used for injecting samples in HPLC?
18. Draw and explain how a six-port valve works.
19. Why are in-line filters used in HPLC systems?
20. What is the composition of the stationary phase and purpose of the guard
column?
21. What are common stationary phases used in reverse phase HPLC?
22. Why do chromatographers purchase their analytical columns instead of self packing their own?
23. How will a poorly packed column affect performance?
24. What is the relationship between performance (resolution) and stationary
phase particle size?
25. Compile a list of HPLC detectors and provide a list of chemicals each can be
used to analyze.
26. Name three advanced types of LC.
27. Why is U-HPLC superior to standard HPLC?
28. How does IC differ from standard HPLC?
29. What is the purpose of the suppressor column in IC?
30. Draw a suppressor column for cation analysis in IC. Explain how it works.
Hope  you  like  the  article. please  leave  a  comment  if  you  have  any  doubts.

Bangalore High Paying Pharma Companies – HYD Delhi Mumbai Chennai

When you want to know the list of bangalore high paying pharma companies for your job search. You have landed a correct destination for your query.

Few big Pharma industries pay well off in many cities. Especially in bangalore you can see companies like Dr Reddy’s Laboratories paying a good amount for their employees of their organization. Even pharma companies like Gland Pharma, Bharat Biotech sun pharmaceuticals, Aurobindo, Mylan Labs, Laurus Laboratories, NATCO Pharma, Divis labs,, Biological-e Ltd, Santha Biotech, Indian Immunological, Cadila, Aventis, are listed in the highest paying pharma companies in India especially in the garden city Bangalore.

There is much scope in many Contract Research Organization. The consulting side of pharma also pays you well. I mean the pay is high. Jobs like Business analyst in life sciences and also like Accenture , cognizant, consulting management officers. there are many options for Pharma graduates. You need to explore it in industrial level.When you look at the pharmaceutical sector in India, most RnD labs are into developmental work in drug discovery. There are a fairly good number of companies in Bangalore working in this area; Syngene International, Jubilant Labs, Aurigene, Advinus Therapeutics etc.

Average starting Salary for Pharma Employees

For your information as per some records the average starting Salary for Pharma Company in India is around ₹1.2 Lakh per year (₹8k to 10kper month). For a fresher who has zero prior experience in a Pharma Company.

What is the highest salary for a Pharma Company in India?

Highest salary that a Pharma Company can earn is ₹6.2 Lakhs per year (₹51.7k per month). Pharma Company salary in India with less than 1 year of experience to 14 years ranges from ₹ 1.5 Lakhs to ₹ 7.1 Lakhs with an average annual salary of ₹ 2.2 Lakhs

Do you know what are High-Paying Jobs In India’s Pharmaceutical Industry:

  •  PharmaCovigilance – Adverse Drug reaction reporting, monitoring and contributing to the central pharmacovigilance commission
  •  Drug Safety Specialist – Involved in the Design and Discovery of new drugs, preclinical testing
  • Quality Assurance Manager – Assures the quality of the Finished Formulations, Manufacturing procedures
  • Quality Control And Validation – validates the processes involved in the manufacture of bulk drugs and formulations QC analyst, QC operator
  • Clinical Pharmacist – Expertise in pharmacotherapy in hospitals and clinics
  •  Academician – to cater the needs of universities and colleges as professor, assistant professor, research assistant.
  •  Manufacturing Chemist – maintenance of pharmaceutical Manufacturing unit, scaleup, tech transfer, supply chain
  •  Chemical Research Analyst – Conduction of human clinical trials and bioequivalence studies
  • Data Analyst – Analyze the clinical Data and provide technical support for the statistical conclusion of the results
  •  Pharma Marketing – national and international marketing of bulk drugs and formulations
  •  Research & Development – New formulation development to enhance the drug delivery and effective treatment

Now comes where you want to go for a high paying Pharmaceutical organizations

Top paying cities for Pharma Jobs in India

• Mumbai – ₹6.1 Lakhs per year

• Hyderabad/Secunderabad – ₹2.7 Lakhs per year

• Indore – ₹1.6 Lakhs per year

• Ahmedabad – ₹1.5 Lakhs per year

• Bengaluru/Bangalore – ₹2.7 Lakhs per year

 

What are the top paying industries for Pharma Students in India?

• Biotechnology

• Pharma

• Healthcare

• NBFC

• Industrial Machinery

What is salary in Cipla pharma?

Average Cipla Pharmaceutical Fresher salary in India is ₹ 1.8 Lakhs for less than 1 year of experience. Fresher salary at Cipla Pharmaceutical India ranges between ₹ 0.2 Lakhs to ₹ 3.2 Lakhs.

Here is the list of some good pharmaceutical companies in Bangalore to work

Syngene

Biocon

Cipla

Caplin laboratories

Apotex Research Pvt Ltd

Hikal Limited

Stabicon Lifesciences Pvt Ltd

Cadila pharmaceuticals

Advinus Therapeutics Pvt Ltd
21 & 22 (Next to NTTF) Phase II Peenya Industrial Area
Bangalore-560058

Alcon Laboratories
Unit No: 502, Tower D, 5th Floor, RMZ Infinity, Benniganahalli, Old Madras Road,
Bangalore-560016

Allergan Services India Ltd
1st Floor, North Wing,Silver Jubilee Block,Mission Road, 3rd Cross
Bangalore-560027

Alltech Biotechnology Pvt Ltd
700/2, New No:3,6th Cross,6th Cross,HAL 2nd Stage,Kodihalli
Bangalore-560038

AstraZeneca India Pvt Ltd
Bellary Road, Hebbal
Bangalore-560024

Aurigene Discovery Technologies Limited
Electronic City Phase II, Hosur Road #39 (P) / 40 (P) KIADB Industrial Area
Bangalore-560100

Avesthagen Limited
Discoverer, 9th Floor International Technology Park Ltd,Whitefield Road
Bangalore-560066

Bal Pharma Ltd.
5th Floor, Laxmi Narayan Complex,10/1, Palace Road
Bangalore-560099

Bangalore Genei Ltd
No. 6, 6th Main BDA Industrial Suburb, Near SRS Road, Peenya
Bangalore-560058

Bhat Bio-Tech India (P) Ltd
No 11-A, 4th Cross, Veerasandra Ind Area, Electronics City
Bangalore-561100

Biocon Ltd
20th KM Hosur Road,Electronics City
Bangalore-560100

Bio-gen Extracts Pvt Ltd
351/6, 14th Cross, Sunkadakatta Magade main Road
Bangalore-560091

British Biologicals
No-30, 10 Main 2nd Block Jayanagar Ashoka Pillar Rode
Bangalore-560011

Carl Zeiss India Pvt Ltd
No. 22 Kensington Road,Ulsoor
Bangalore-560008

Clinigene International Limited
Clinigene House”Tower 1, Semicon Park,Electronic City, Phase II,Hosur Road
Bangalore-560100

CytoGenomics India (P) Ltd,
3004, 12A Main HAL 2nd Stage
Bangalore-560008

Essilor India Pvt Ltd
No. 71/1, S.C.Road,Brigade Plaza,6th Floor,Anand Rao Circle,Gandhinagar
Bangalore-560009

Genotypic Technology Pvt Ltd
112/113, Embassy Center, # 11 Crescent Road, High Grounds
Bangalore-560001

Global Calcium Private Limited
No.1, Hundred Feet Road, 5th Block, Koramangala
Bangalore-560095

Greenearth Biotechnologies Ltd
14-A, Jigani Industrial Area, Anekal Taluk
Bangalore-562106

HealthScribe India Pvt Ltd
One HealthScribe Plaza, Koromangala Block 8
Bangalore-560095

Indfrag Ltd
1320, 12th Cross, Indiranagar II Stage
Bangalore-560038

Ittina Healthcare Pvt Ltd
No. 380, 16’th Main, 3’rd Block, Koramangala
Bangalore-560034

Jubilant Biosys Ltd
96, Industrial Suburb, 2nd Stage, Yeshwantpur
Bangalore-560022

Karnataka Antibiotics & Pharmaceuticals Ltd
No.14, 2nd Phs, Peenya
Bangalore-560058

Kemwell Pvt Ltd
34th KM, Tumkur Road, Teppada Begur, Nelamangala Taluk
Bangalore-562123

Lifeken Healthcare Pvt Ltd
45 / B Shubam , 3rd Floor, Sarakki Industrial Area 1st A , Main Road, J.P. Nagar III Phase
Bangalore-560078

Lotus Labs Pvt Ltd
No 7, Jasma Bhavan Road, Opp. Gurunanak Bhavan, Millers Tank Bed Area, Vasanth Nagar
Bangalore-560023

Medreich Sterilab Limited
Medreich House, No. 12/8,Saraswati Ammal Street, M.S. Nagar
Bangalore-560033

Metahelix Life Sciences Pvt Ltd
Plot No. 3,KIADB 4th Phase, Bommasandra Industrial Area
Bangalore-562158

Micro Labs Ltd
No.27,kcn Towers, Race Course Road
Bangalore-560001

Millipore (India) Pvt Ltd
No. 50A, 2nd Phase, Peenya, Ring Road
Bangalore-560058

Molecular Connections Pvt Ltd
Kandala Mansions, #2/2, Kariappa Road (South Cross Road), Basavanagudi
Bangalore-560078

Multiplex Biotech Pvt Ltd
180, 1st Main Road, Mahalakshmi Layout Extension
Bangalore-560086

Natural Capsules Ltd
102, Shreshta Bhumi No. 87, K.R. Road
Bangalore-560004

Novo Nordisk India Pvt Ltd
8th Floor, Raheja Towers, 26/27, M. G. Road
Bangalore-560001

Novozymes South Asia Pvt Ltd
No.9, 1st Flr, Itpl, Innovator, Whitefield
Bangalore-560066

Ormed Medical Technology Ltd
No 27 A Electronic City Phase I
Bangalore-600098

PharmARC Analytic Solutions Pvt Ltd
Mercury 2B Block, 6th ,Floor, Prestige,Technology Park,Sarjapur – Marathahalli Outer Ring Road,,
Bangalore-560087

Pharmed Medicare
Pharmed Gardens, Whitefield Road
Bangalore-560048

Sami Labs Ltd
19/1 & 19/2 I Main II Phase Peenya Industrial Area
Bangalore-560058

Sartorius India Pvt

Do you know yearly salary growth in Pharma?

Career timeline and salary growth will always depend your own decision. As many organizations give good salary but there is only a little hike at the end of every year. If you wish to grow more in terms of salary you need to choose top 10 list of pharma companies you wish to work for and crack job with your experience every couple of years. This is my view and others view might be different.

 

Indian Pharmaceutical Companies List + Company Name Address You might not Know

Company Name and Address
Amol Pharmaceuticals Pvt. Ltd.,
E1-362-363, Sitapura Industrial Area,
Jaipur – 302 022, Rajasthan
Medicamen Biotech Limited,
10, Community Centre No. 2,
Ashok Vihar, P-II, New Delhi – 52
Medicamen Organics Limited,
10, Community Centre No. 2,
Ashok Vihar, P-II, New Delhi – 52
Next Wave (India),
C-980, Sushant Lok, Phase – I,
Gurgaon – 122 002, Haryana
Petlad Mahal Arogya Mandal Pharmacy,
Punarvasu, Near Railway Crossing,
Petlad Road, Nadiad – 387 002, Gujarat
Allied Chemicals & Pharmaceuticals Pvt. Ltd.,
Rajnigandha Complex, 8734,
D.B. Gupta Road, Pahar Ganj,
New Delhi – 110 055
Jocund India Ltd.,
Rom No. 101, Rajnigandha Complex,
8734, D.B. Gupta Road,
Pahar Ganj, New Delhi – 110 055
J. Duncan Healthcare Pvt. Ltd.,
Plot No. 65, 66 & 67, Phase – II,
Atgaon Industrial Complex,
Mumbai Nashik Highway,
Shahpur – 421 601, Maharashtra
Pharma Synth Formulations Ltd.,
Plot No. 18-22, Sector 6-B,
SIDCUL Integrated Industrial Estate,
Haridwar – 249 403, Uttarakhand
Pharmchem,
64, Ajmal Khan Park, Karol Bagh,
Delhi – 110 005
Similax Pharmaceuticals,
11 K.M. Stone, Tonk Road,
P.O. Airport, Sanganer, Jaipur – 302 011
Ravenbhel Healthcare Pvt. Ltd.,
16-17, Export Promotion Industrial Park,
SIDCO, Kartholi, Bari Brahmana,
Jammu – 181 133, J & K
Syncom Healthcare Ltd.,
Syncom House, 40, Niranjanpur,
A.B. Road, Indore – 452 010,
Madhya Pradesh
Agrawal Drugs Pvt. Ltd.,
24/6B, IIE, SIDCUL,
Haridwar – 249 403, Uttarakhand
SG Pharma Pvt. Ltd.,
542, 3/10, Bhuta Niwas,
Dr. Ambedkar Road, Matunga (E),
Mumbai – 400 019, Maharashtra
Prashanti Formulations Ltd.,
Village Nangal Shaheedan, Chandigarh Road, Hoshiarpur – 146 001, Punjab
Dr. Sabharwal’s Wound Care,
260, Sector 6, Panchkula – 134 109,
Haryana
Global Pharma Healthcare Pvt. Ltd.,
A9, SIDCO Pharmaceutical Complex,
Alathur, Thiruporur  – 603 110, Tamil Nadu
Vetsfarma Ltd.,
Village Daulatpur, P.O. Khadd,
Distt. Una – 177 207, Himachal Pradesh
Synmedic Laboratories,
202, Sai Plaza, Sant Nagar,
East of Kailash, New Delhi  – 110 065
Chimak Health Care,
Padmalya, Bye Pass Road,
kather, Solan – 173 212, Himachal Pradesh
Palson Drugs Private Ltd.,
10/D/1, Ho-Chi-Minh Sarani,
Kolkata – 700 071, West Bengal
Synkrom Healthcare Private Limited,
E-226, Industrial Area,
Phase – VIII B,
Mohali – 160 071, Punjab
Dr. Dozo Laboratories,
419, Industrial, Phase – IX,
S.A.S Nagar (Mohali) – 160 062
Oniosome Healthcare Pvt. Ltd.,
# E 226, Phase VIII-B, Industrial Area,
S.A.S Nagar (Mohali) – 160 071
Stallion Laboratories Pvt. Ltd.,
817, Devpath, Behind Lal Bunglow,
Off. C.G. Road, Ahmedabad – 380 006
Apex Drug House,
28, Mehta Vora Chamber (Mahindra Mansion),
2nd Floor, Babu Genu Road, Mumbai – 400 002
Unijules Life Sciences Ltd.,
1505/1, Universal Square,
Shantinagar, Nagpur – 440 02
Ciron Drugs & Pharmaceuticals Pvt. Ltd.,
1, Prabhat Nagar, Jogeshwari – W,
Mumbai – 400 102
R.L. Fine Chem,
Ray House, HIG NO. 2000,
Yelahanka New Town, Bangalore – 560 106
Samrudh Pharmaceuticals Pvt. Ltd.,
A/101, Prarthana Apartment,
SV Road, Goregaon West,
Mumbai – 400 062
M.B. Sugars and Pharmaceuticals Ltd.,
Lodha Bhuvan, P.B. NO. 31, Malegaon,
Distt Nasik – 423 203
Symbiotic Pharmalab Ltd.,
385/2, Pigdamber, Rau,
Indore – 453 331
Gufic Biosciences Ltd.,
Old Sanskar Jyot School Building,
S.V. Road, Andheri (W),
Mumbai – 400 058
Andel Equipment Pvt, Ltd.,
289, Industrial Area, Phase – 9,
S.A.S. Nagar (Mohali) – 160 062
Adlife Healthcare Pvt. Ltd.,
2B-002, N.G. Suncity, Thakur Village,
Kandivali (E), Mumbai – 400 101
Mediwin Pharmaceutical,
703, Sakar – III, Opp. Old High Court,
Income Tax, Ahmedabad – 380 014
Eastern Chemicals,
601, 6th Floor, Morya Landmark – II,  Oshiwara Link Road, Opp. Infinity Mall, Andheri (West) – 400 053, Mumbai
Aurochem Pharmaceuticals (India) Pvt.  Ltd.,
334, 3rd Floor, Gundecha Ind. Complex, Akurli Road,  Kandivali (E), Mumbai – 400 101
Aurochem Laboratories (India) Pvt.  Ltd.,
333, 3rd Floor, Gundecha Ind. Complex, Akurli Road,  Kandivali (E), Mumbai – 400 101
Ban Lab Ltd.,
Ban House, Gondal Road, Rajkot – 360 004, Gujarat
Medibios Laboratories Pvt.  Ltd.,
102, Mangalam, Kulupwadi Borivali (East), Mumbai – 400 066
Emil Pharmaceutical Inds Private Ltd.,
101, Mangalam, Kulupwadi Borivali (East), Mumbai – 400 066
Relax Pharmaceuticals (P) Ltd., Unit –I,
48-AB, Gondpur Industrial Area, Paonta Sahib – 173 025, Himachal Pradesh
Mediforce Healthcare Pvt. Ltd.,
46, Gondpur Industrial Area, Paonta Sahib
Copmed Pharmaceuticals, Unit – I,
Plot No. 4-A/B, Gondpur Industrial Area, Paonta Sahib
Pharma Force Lab.,
53-55, Gondpur Industrial Area, Paonta Sahib, Distt. Sirmour
Sirmour Remedies Pvt. Ltd.,
Village Kyarda, P.O. Misserwala, Nahan Road, Paonta Sahib
Pharam Force Lab. Unit – II,
Chaman Vatika, Puruwala Village, Nahan Road, Paonta Sahib
Mankind Pharma Ltd. Unit III,
Village Kunja, Rampur Ghat Road, Opp. Dental College, Paonta Sahib
Care Cosmetics
Behind Patwar Bhawan, Moginand, Kala Amb – 173 030
Sunvet Pharma Pvt. Ltd.,
Village Upper Moginand Nahan Road, Kala Amb, Sirmour
Zim Laboratories Ltd.,
B-21/22, MIDC Area, Kamleshwar – 441501, Nagpur
Malviya Chemicals & Pharmaceuticals Pvt. Ltd.,
Plot No. 34A/2, Site 4, Sahibabad, Uttar Pradesh
Fermenta Biotech Limited
Village Takoli, P.O. Nagwain, Distt. Mandi – 175 121
Kudos Chemie Ltd.,
Kuranwala, Barwala Road,
Derabassi – 140 507
Scott-Edil Pharmacia Ltd.,
56, E.P.I.P. Phase – I, Jharmarjri, Baddi, Distt. Solan
Chemical Resources,
SCO No. 76, 1st Floor, MDC, Swastik Vihar, Panchkula  – 134 109
Supreme Pharmaceutical Private Ltd.,
73, 74 & 48PI, KIADB Industrial Area, Nanjagurd – 571 302, Mysore
Overseas Health Care Pvt. Ltd.,
335 KM Milestone, NH 1, P.O. Box 25, Phillaur – 144 410
Cooper Pharma Ltd.,
12/12, Shakti Nagar, Delhi – 110 007
Gracure Pharmaceuticals Ltd.,
71/5, Najafgarh Road (Shivaji Marg), New Delhi – 110 015
Cris Pharma (India) Ltd.,
E-11, UPSIDC Industrial Area, Selaqui – 248 197, Dehradun
Indus Pharma (P) Ltd.,
5/2, Ind. Area, Kirti Nagar, New Delhi – 110 015
Wallace Pharmaceuticals Pvt. Ltd.,
Village Bhatian, Tehsil Nalagarh, Distt. Solan – 174 101, H.P.
Tirupati Life Sciences,
Surjpur, Nahan Road, Paonta Sahib – 173 025, Himachal Pradesh
Tirupati Medicare Ltd.,
Near Fire Station, Nahan Road,
Paonta Sahib – 173 025
Galpha Laboratories Ltd.,
Village Thana, Baddi, Distt. Solan, Himachal Pradesh – 173 205
Vamsi Labs. Ltd.,
A-14115, MIDC Area, Chincholi,                         Solapur – 413 255
Health Biotech Limited,
SCO : 162-164, Air India Building,                           Top Floor, Sector – 34A,
Chandigarh – 160 022
Coral Drugs Pvt. Ltd.,
Plot No. 55-56, HSIIDC Industrial Estate, Murthal, Sonepat – 131 039
Embotic Laboratories. Ltd.,
20C, Kumbalagodu Industrial Area , Bangalore, Karnataka – 560074
Pharmaffilites analytics. P Ltd.,
225, Industrial Area , Phase 2, Panchkula, Haryana – 134109
Parex Pharmaceticals Ltd,
D 145, Phase 7 Industrial Area , Mohali, Punjab – 160055
Saurav Chemicals Ltd,
Derabassi Barwala Road,Vill. Bhagwanpura , Mohali, Punjab – 140507
Venus Remedies Ltd,                                  51-52,Industrial Area Phase 1 , panchkula 134113
Simson Pharma,B-307, sarita building, Prabhat Ind. Estate, Dahisar(E), Mumabi-400068
Nirwana Herbal Healthcare E-38,Industrial Area,Yamuna Nagar 135001 ( Haryana)
Camphor and Allied products LimitedCamphor officers colony bareilly (UP
Nanz Med Science Pharma Private Ltd  vill Rampur Ghat, tesil Paonta sahib sirmaur HP
Infinity Laboratories Pvt Ltd.,            Vill.BEHRA,Derabassi,Distt. Mohali,Punjab
Shaleen Pharmaceticals,
53,  Industrial Area  Phase 1, Panchkula – 134113
Pharma Impex Limited,
620, Diamond Harbour Road,                           Behla Industrial Estate, Kolkota,
Mehta API Ltd,
Gut No 546, plor no N-211,Vill. kumbhavli ,Taluka Palghar , Thane-4014506
GPR Life Sciences Pvt. Ltd.,                    Plot no.66E,66F,KIADB,Industrial Area,Humnabad,Karnataka
620, Diamond Harbour Road,                           Behla Industrial Estate, Kolkota,
Alice Health Care, C-44,Industrial Area,Phase -3, Mohali-PB
Hiral Labs Ltd.,265, SISONA Nr Bhagwanpur, Roorkee,Distt. Haridwar Uttarakhand
Austin Pharmaceuticals Ltd.                      E-40,IFP,DeraBassi
Corona Remidies Ltd.,
Vill Jatoli, Solan, HP
Alliance Formulation Ltd.,
30B, EPIP, Phase 1, Jharmajari, Baddi, HP – 174103
Windlas Biotech Limited
40/1, Mohabewal Indusrial Area, Dehradun, UK 248110
Windlas Healthcare Limited
Plot no 183,192, Mohabewal Indusrial Area, Dehradun, UK 248110
Martin&Brown Bio-sciences, Malkhumajra,P.0. Bhud, Baddi, Distt. Solan(HP)
Ark Health care (P) Ltd.,
D-12, Focal Point, Dera Bassi, Punjab,140201
Worldwide Herblife Ltd.,
B-09, Focal point, Derra Bassi,
Punjab
Aspen Lifesciences,                                  Plot no. 29,verka valla bypass, Amritsar,Punjab
Chethna formulation  Ltd.,
PO Anamangad, perintalmanna, Kerala 679357
Celeste Life Sciences Pvt. Ltd.,                       C-98, 2nd Floor, Sec.-.65,Noida(UP)-2013017
Vindas Chemical Industries Pvt. Ltds., Plot no.65, SEC.1, Pithampur,Distt. Dhar,M.P.-454775
Chandigarh Agritech Pvt. Ltd.,141,1ST Floor,TricityPlaza Mall,Peermoshalla-160104(Dhakoli),Punjab
M/S Vedant Incorporation,G-1,249&250, Industrial Area,Khushkhera, Bhiwandi, Rajasthan
M/S Torque Pharmaceuticals Pvt. Ltd. Issapur.P.O.Dappar,THE:. DeraBassi,Distt. SAS Nagar
M/S Laxon Drugs Pvt. Ltd.,D-48, Focal Point, DeraBassi
M/s Biogenetic Health Care,C-148, Focal Point,Patiala
M/s Gary Pharmaceuticals Pvt. Ltd,OFF NH-95, VPO.HEERAN, Ludhiana,Punjab
M/s Consern Pharma Pvt. Ltd., Rural Focal Point,VPO TIBBA- Sahnewal, Distt. Ludhiana-141120 Punjab
Pharma Cure Laboratories,Near Govt. School, GARHA,Jalandhar- 144022, Punjab
Unitech Pharmaceuticals Pvt. Ltd., 5,Adarsh Colony, Barewal Road, Behind PNB,Ludhiana-141012-Punjab
AripolisBoitech Pvt Ltd,111, Mahabir Nagar, opposite-MBD Mall, Ludhiana-141012,Punjab
Upsilon Pharma Labs,SIDCO IGC, Lassipora, Pulwama, J&K
Mahima Life Sciences Pvt Ltd,BST Road, Ganaur-131101 Dist Sonepat Haryana
Company name Address
DIL limited Ghodbunder Road, Thane (West) – 400 610, India. Email:[email protected]   Mr. Srikant Sharma
Compliance Officer
Tel: + 91 22 6798 0888
Fax: + 91 22 6798 0889
Email: [email protected]
Dishman Pharmaceuticals and Chemicals Ltd. Bhadr-Raj Chambers
Swastik Cross Road, Navrangpura
Ahmedabad – 380 009
Gujarat, India
Tel:  +91(79) 26443053
+91(79) 26445807
+91(79) 26560089
Fax: +91(79) 2642-0198
[email protected]
Divis Laboratories Limited Divi Towers, 7-1-77/E/1/303,
Dharam Karan Road, Ameerpet,
HYDERABAD – 500 016.
Andhra Pradesh, India.
Phone: +91 (40) 2378 6300.
+Fax: 91 (40) 2378 6460.
Email: [email protected]
Dr. Reddy’s Laboratories Limited Door No 8-2-337,
Road No 3, Banjara Hills,
Hyderabad – 500034.
Andhra Pradesh
Tel: +91-40-49002900
Fax: +91-40-49002999
Visit: www.drreddys.com
Elder health care ltd C-9, Dalia Industrial Estate,
Off New Link Road ,
Andheri (W),
Mumbai 400 058
INDIA
Tel : +91-22-2673 0058 – 67
Fax : +91-22-2673 0051
E-mail : [email protected]
Elder pharmaceuticals ltd. Elder House
C-9, Dalia Industrial Estate,
Off Veera Desai Road , Andheri (W),
Mumbai 400 053.
INDIAContact :
Tel : +91-22-2673 0058 – 67
Fax : +91-22-2673 0051
E-mail : [email protected]
Elder projects ltd. Plot No. A-38/1, Patalganga Industrial Area,
Village Khaire, Taluka – Khalapur,
District – Raigad,
Maharashtra 410 220
Tel 02192-250020 Fax – 02192-250019
Electrosteel Castings Limited G.K. TOWER
19, Camac Street
Kolkata – 700 017
Ph. No.+91-33-22839990/ 40090600
Fax No.
+91-33-22894336 (Directors)
+91-33-22894337 (Sales)
+91-33-2289-4338 (Export)
+91-33-22894339 (Finance)
Everest organics ltd. Plat No. 127.128
Kavuri Hills, Mahdapur
Hyderabad – 500033Tel : +91 40 23115956
+ 91 40 40040783
+ 91 40 23115951

Fax : +91 40 23115954

Fresenius Kabi Oncology Limited Echelon Institutional Area
Plot No-11, Sector – 32
Gurgaon
Pin code – 122001
Haryana, India

Ph : +91 124 4885000 / +91 124 3325000
Fax : +91 124 4885003
E-mail : [email protected]

Fulford (India) Ltd.,  

​Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) ,   Mumbai – 400098,
Tel: +91 22 67898888; Fax: +91 22 67898889
Email is at:    [email protected]

Gennex Laboratories Limited Address :Gennex Laboratories Limited ‘Akash Ganga’ 3rd Floor, Plot No. 144, Srinagar Colony Hyderabad – 500 073 (A.P) India
Phone :+91-40-67334400 (30 lines) / 23746451
Fax :+91-40-67334401/33
Email :[email protected]
GlaxoSmithKline Pharmaceuticals ltd. Address:  Near Doordarshan, Dr Annie Besant Road, Worli New, Mumbai – 400030 Sangeeta Sharma                                                                                                   Tel: +91 22 2495 9595,  (022) 24959494                                                                                       Email: [email protected][email protected]
Glenmark Pharmaceuticals Limited Glenn Saldanha
Glenmark House,
B D S Marg,
Chakala, Off Western Express Highway
Andheri (E), Mumbai – 400099
Tel : +91 22 4018 9999
Fax : +91 22 4018 9990
Email Address :     [email protected]
Godavari Drugs Limited 1st Floor, Mayfair, Sardar Patel Road, Secunderabad,500003‎, Andhra Pradesh, India.Phone: + 91 – 40 – 2784 2602
FAX     : + 91 – 40 – 2784 9859
Email  : [email protected]
Gufic Biosciences Ltd. Subhash Road-A, Vile Parle (East),
Mumbai-400 057
Phone: 022-56919191,
Fax: 022-26169008, 26118103
E-mail: [email protected]
Gujarat Inject (Kerala) ltd. Dwipa Y Mankodi                   Director
Ami Y Mankodi                       Director
Village Pampampallam,
Pudussery East,
Palakkad – 678625,
Kerala
India
Tel: 91-491-62369 / 62370
Fax No.: 91-491-62208
Gujarat Terce Laboratories Ltd. 122 / 2, Ravi Estate, Bileshwarpura, Chhatral,
Dist: Gandhinagar, Gujarat, INDIAPhone: 02764 23182
Email: [email protected]
Harleystreet Pharmaceuticals Ltd.                                                                                                           Other Office                                                      Harleystreet Pharmaceuticals Limited
Plot No. 29/3,
Phase III, GIDC Industrial Estate,
Naroda,
Ahmedabad – 382 330
India
Tel: 91-79-22830420
Fax: 91-79-22822133
E-mail: [email protected]
Hindustan Bio Sciences Ltd. H No. 8-2-269/S,
Plot No : 31,,Sagar Co-Operative Housing Society,
Hyderabad
Andhra Pradesh
500034Tel: 040-23555161
Fax: 040-40205171
Email: [email protected]
Website: http://www.hindustanbiosciences.com
Hiran Orgochem Ltd. 601, A/1, M Block,
Palm Court, Link Road,
Malad (West), Mumbai – 400 064.
India.
Tel. No.: + 91 – 22 – 4095 3000 (60 lines)
Fax. No.: + 91 – 22 – 4095 3099Others: [email protected]
For any information / inquires:
Director International Business
Mr. Naresh Hiran
Office contact No: + 91 – 22 – 4095 3000
[email protected]
Sharon Bio medicine Ltd. C-312, BSEL Tech Park, Sector 30(A), Vashi, Navi Mumbai-400703.                              Ph. : 91 22 67944000.     Fax : 91 22 67944001.                                                                         General: [email protected]
Shasun Chemicals & Drugs Ltd. 3rd & 4th Floor,
‘Batra Centre’,
28, Sardar Patel Road,
Guindy, Chennai 600032,
Tamil Nadu, India.Tel : +91-44-43446700 Fax: +91-44-22350278  Email: [email protected]
Shilpa Medicare Ltd. 10/80, RAJENDRA GUNJ,
RAICHUR – 584 102 (INDIA)
Tel.: ++91-8532-235006
Fax: ++91-8532-235876
E-MAIL: [email protected]
Siris Ltd. Flat No 206 Chandra Towers,Behind Madhu Kalyanamandapam ,MogalrajapuramVijayawada-520010, Andhra Pradesh
www.siris.com
Chairperson –
MD – G Rama Raju
Smruthi Organics Ltd. Corporate Office

165A Balaji Bhavan, Railway Lines
Solapur, Maharashtra . India – 413001
Ph ++91 – 217 – 231- 0267
Ph ++91 – 217 – 231- 0367
Fax ++91 – 217 – 231- 0268
e – mail Smruthi Organics Solapur

SMS Pharmaceuticals Ltd. Regd.off:Plot No:19-III,Road No:71,Jubilee Hills,
Opp.Bharatiya Vidya Bhavan Public School.HYd-34.
Phone : 040-66288888
Fax : 040-23551401,23551402
Email : [email protected]
Solvay Pharma India Ltd. Amalgamated Corporate Address :      271, Business Park,6th &7th Floors,Model Industrial Colony,off Aarey Road,Goregaon (East)Mumbai-400063, Maharashtra
www.solvaypharma.co.in Tel: 022- 24372646 24376533 24372983, 91-22-2871 7400/91-22-4244-7400
MD – Niteen B Gadgil
Sree Rayalaseema Alkalies & Allied Chemicals Ltd. Corporate Office:     40-304,2nd floor, K.J.Complex,
Bhagyanagar, Kurnool 518004, (A.P)
Ph. No. ; 08518-289602/03,221933/0069
Fax No. : 08518-226973/222745                                                                                                    Contact Person : Mr. A.T.Sathyanarayana
Address : 25, 1st floor, Radha Nivas, Shankara Park Road, Shankara Puram
City : Bangalore
State : Karnataka
Country : India
Pin Code : 560004
Phone : +91-80-26608884 / 32954744
Fax : +91-80-22423655
Email Address : [email protected]
Mobile : +91-9343004285
Web Site : http://www.sreerayalaseemaalkalies.com
SS Organics Ltd.  Corporate Office:     Survey No 252/1,Aroor Village ,Sadasivapet MandalMedak-502291, Andhra Pradesh
www.ssorganicsindia.com                 Tel.  250280  / 250080
Fax  310701     Email: [email protected]
Sterling Biotech Ltd. Mumbai Office:
C – 25, Laxmi Towers,
‘A’ – 601, 6th Floor,
Bandra Kurla Complex,
Bandra (East)
Mumbai – 400051
Tel. No. : +91-22-26541241/42/43
Fax No. : +91-22-26540155 Email: [email protected], [email protected]
Baroda Office:
Sandesara Estate, Padra Road,
Atladra, Vadodara – 390012,
Gujarat, India.
Tel. No. : +91-265-2680720/30
Fax No. : +91-265-2680257/732
Sun Pharma Advanced Research Company Ltd. SPARC
Sun Pharma Advanced Res Centre,
Akota Road Akota,
Vadodara,
Gujarat.
Tel : 91-265-2330815
Fax : 91-265-2354897
Email : secretarial:sparcmail.com
Website : http://www.sunpharma.in
Strides Arco Lab Ltd. Corporate Office : Strides Arcolab Limited
Strides House, Bilekahalli, Bannerghatta Road,
Bangalore – 560076, IndiaTel: +91 80 6784 0000 / 6784 0738
Fax: +91 80 6784 0700 / 6784 0800

Registered Office :

201, Devavrata, Sector 17,
Vashi, Navi Mumbai – 400 703, India
Tel: +91 22 2789 2924/ 2789 3199
Fax: +91 22 2789 2942

Website: www.stridesarco.com
E mail: [email protected]

Sun Pharmaceutical Inds. Ltd Acme Plaza,
Andheri – Kurla Rd
Andheri (E)
Mumbai – 400 059
India
Tel : (+91) 22 6696 9696
Fax : (+91) 22 2821 2010
Supriya Pharmaceuticals Ltd. Corporate Address                                                                                                                           F-530, Riico Industrial Estate, AlwarBhiwadi-301019, Rajasthan 301019                              Tel: 01493- 220053 220754
Surya Pharmaceuticals Ltd. HEAD OFFICE
1596 First Floor,Bhagirath Place,
Chandni Chowk, Delhi – 110006

[email protected]   [email protected]
[email protected]

Suven Life sciences Ltd. Serene Chambers,
Road No. 5, Avenue – 7, Banjara Hills,
Hyderabad-500 034, A.P., INDIAPhone : +91-40-2354-1142, 2354-3311 ,
3292-1694/97
Fax     : +91~40~2354-1152
Email id: [email protected]
Sword & Sheild Pharma Ltd. Regd office :
311, Rajkamal Plaza-B,
4/B, Sattar Taluka Society,
Opp. Old High Court,
Ahmedabad-380014Phone : (079) 27543290
Works :
3001/M, G.I.D.C.,
Phase III. Chhatral-382 729,
(n. Gujarat)

Phone : (02764) 233322
Email : [email protected],
[email protected]

Syncom Formulations (India) Ltd. Head Office
5, Niraj industrial Estate,
Off Mahakali Caves Road,
Andheri (East), Mumbai 400 093,
India.
Telephone
022 – 30887744
Fax
022 – 30887755
Email
[email protected]                                                                                                          Corporate Office
2nd Floor, ‘Tagore Centre’ (Dawa Bazar),
13-14, R. N. T. Marg,
Indore (MP) 452 001
Telephone
:91-0731 – 3046868/69/70/71
Fax :
91-0731 – 3046872
Themis Medicare Ltd. 11/12, Udyog Nagar,
S.V.Road, Goregaon (West),
Mumbai-400 104.
INDIATel:  +91 22 6760 7080
+91 22 2875 7836
Fax: +91 22 2874 6621
Torrent Pharmaceuticals Ltd. Regd. Office
& Corporate Office  :    Off. Ashram Road,
Ahmedabad – 380 009.
Gujarat, India
Phone : General EPA BX :
91 – (0)79 – 26585090/3060
Fax :
91-(0)79-26582100                                                                                                                        Research Centre Address:                                                                                                             Nr. Kanoria Hospital,
Village Bhat,
Dist. Gandhinagar,
Pin : 382428
Gujarat, IndiaPhone :
91-(0)79-23969100
91-(0)79-23969124-34

Fax : 91-(0)79-23969135

Email : [email protected]

Trans Asia Corpn. Ltd. 301, Mehta Estate, 3rd Floor,
Chakala, Andheri – Kurla Road,
Andheri (E) Mumbai – 400 093, India.
Telefax: 91-22-26836554
E-mail: [email protected]
Transchem Ltd. 304, Ganatra Estate, Pokhran Road No.1,
Kopat, Thane(W) – 400 601Telephone: 022-2547 7077
Telefax: 022-2547 8601

Email: [email protected]

Triochem Products Ltd. Corporate Address:  Sambava Chambers,4th Floor,Sir P M Road FortMumbai-400001, Maharashtra
www.tricheminc.net
TTK Healthcare Ltd. 6, Cathedral Road,
Chennai – 600 086.
Phone: +91 44 28116108/ 09/ 10
Email: [email protected]
Twilight Litaka Pharma Ltd. B-22 “H” Block
M.I.D.C. Pimpri, Pune 411 018,
Maharashtra, India
Tel: (91-20) 30642650/51/52
Fax: (91 20) 27475862
E-mail : [email protected]
Web : www.twilightlitaka.com
Unichem Laboratories Ltd. Unichem Bhavan
Prabhat Estate, Off S.V.Road,
Jogeshwari (West),
Mumbai – 400 102
Tel: + 91 022 66 888 333
Fax: + 91 022 2678 4391 / 2678 8665
Unjha Formulations Ltd. Khali Char Rasta, State Highway
Sidhpur – 384151
Gujarat
IndiaEmail : [email protected]
[email protected]

 

List of Material Manufacturing Companies Chennai Tamil Nadu

The pharmaceutical industry and other departments of raw materials like chemical, fertilizer, metal , glass are major manufacturing industries in the world. The pharmaceutical industry is responsible for the production of medicines and other medical products. It also has a huge demand for raw materials, including drugs and chemicals, construction materials.

In this section, we will talk about the various aspects of pharmaceutical material manufacturing companies along with other industries and the list in Chennai Madras. We will talk about their different types, their advantages and disadvantages, as well as their role in today’s market place.

Construction Materials

Company Name Company Type Company Status Sub Industry Website
Anabond Ltd. Private Company Operating Commodity Chemicals http://www.anabond.com
Avnija Properties Ltd. Private Company Subsidiary Construction Materials
Cetex Petrochemicals Ltd. Private Company Operating Commodity Chemicals http://www.cetexpetro.com/
Chemplast Sanmar Ltd. Public Company Operating Commodity Chemicals http://www.sanmargroup.com/chemicma.htm
Chettinad Cement Corporation Ltd. Public Company Operating Construction Materials http://www.chettinadcement.com
China Forestry Holdings Group Private Company Operating Forest Products
Dalmia Bharat Enterprises Ltd. Public Company Operating Construction Materials http://www.dalmiacement.com/
Finer Enterprise Pvt. Ltd. Private Company Operating Paper Packaging http://finergroup.com
Gem Granites Pvt. Ltd. Private Company Operating Construction Materials http://www.gemgranites.com
India Cements Ltd. Public Company Operating Construction Materials http://www.indiacements.co.in/
Kothari Petrochemicals Ltd. Private Company Subsidiary Commodity Chemicals http://kotharipetrochemicals.com/
Manali Petrochemical Ltd. Public Company Subsidiary Commodity Chemicals http://www.manalipetro.com
Nelcast Ltd. Public Company Operating Steel http://www.nelcast.com/
Packaging India Pvt. Ltd. Private Company Subsidiary Metal & Glass Containers http://www.packaging-india.in/
Rentokil India Pvt. Ltd. Private Company Operating Fertilizers & Agricultural Chemicals http://www.rentokil.in/
SBQ Steels Ltd. Private Company Operating Steel http://www.rkkrgroup.com/html/sbqsteels.html
Sree Ganga Steels Ltd. Private Company Subsidiary Steel http://www.smsteels.com/
Sree Ramcides Chemicals Pvt. Ltd. Private Company Operating Fertilizers & Agricultural Chemicals http://www.ramcides.com/
Tuticorin Alkali Chemicals and Fertilisers Ltd. Public Company Operating Fertilizers & Agricultural Chemicals
Viki Industries Pvt. Ltd. Private Company Operating Steel http://www.isteel.in
Vinplex India Pvt. Ltd. Private Company Merged Construction Materials

In the industrial space today, there are several types of pharmaceutical manufacturers. These companies have different advantages and disadvantages. The types of pharmaceutical companies that you can find in the marketplace today are:Pharmaceutical companies manufacture medicines and other medical devices used in treating. The pharmaceutical industry is a major manufacturing industry in the world. The pharmaceutical industry is responsible for the production of medicines and other medical products. It also has a huge demand for raw materials, including drugs and chemicals.
In this section, we will talk about the various aspects of pharmaceutical material manufacturing companies. We will talk about their different types, their advantages and disadvantages, as well as their role in today’s marketplace. .In the marketplace today, there are several types of pharmaceutical manufacturers. These companies have different advantages and disadvantages. The types of pharmaceutical companies that you can find in the market pl care, including health information processing and technology.Pharmaceutical companies manufacture a wide variety of medicines and other medical devices;These types of pharmaceutical manufacturers are used when there is no FDA approval for a particular drug in the market place.As mentioned before, there are different types of pharmaceutical manufacturers that produce different kinds of medicines. The two most common medical of area the in products other ace today are:Pharmaceutical companies manufacture medicines and other medical devices used in treating diseases like cancer, diabetes and other chronic conditions;Pharmaceutical companies also manufacture a variety ong diseases like cancer, diabetes and other chronic conditions;Pharmaceutical companies also manufacture a variety of drugs and medical devices;Pesticides;Antibiotics;Drugs to treat epilepsy, depression and anxiety disorders.

PEBC Indian Pharmacy Graduates Guide Registered CANADIAN PHARMACIST & Pharma Assistant

Pharmacy is a key sector of the economy in Canada. There are many different types of pharmacies, such as independent and community pharmacy, drug stores, hospital pharmacies, laboratories and clinics. The scope of pharmacy education has been expanding in different areas. In the past few years there has been a rise in the number of pharmacist schools and more universities offering Pharmacy degrees. This growth is due to the increasing demand for pharmacists and their knowledge about drugs, patient care and pharmaceutical products. .Scoring and Qualifications of Pharmacy Degrees There are different types of degrees available in pharmacy, some more rigorous than others. The degree requirements can vary depending on the university offering the program and where it is offered. In addition to basic undergraduate courses, a number of pharmaceutical related programs are available at postgraduate level. These programs include pharmacotherapeutics, Pharmacology, Medicinal Chemistry.

Canadian PEBC Certification Process for International Students

The process of becoming a licensed pharmacist in Canada involves completing a series of Exams with few steps. There are 3 steps to achieving PEBC pharmacist certification:

STEP 1

DOCUMENT EVALUATION – You must pass this evaluation of your educational and professional credentials to be eligible to take the Pharmacist Evaluating Examination.

STEP 2

THE PHARMACIST EVALUATING EXAMINATION – You must pass this examination to be eligible for the Pharmacist Qualifying Examination – Parts I (MCQ) and II (OSCE).

STEP 3

THE PHARMACIST QUALIFYING EXAMINATION, PART I (MCQ) and PART II (OSCE) – Your final step to qualifying for certification with PEBC. When you have passed both Parts of the examination you will be certified and registered with PEBC.

Documents Required for Canada Pharmacist Exam

The process of becoming a licensed pharmacist in Canada involves PEBC certification. For these exams is the Pharmacy Examining Board of Canada (PEBC) Qualifying Examination One need to have a Pharmacy graduate Degree. PEBC will evaluate your degree convocation marks lists of all the years of your academics documents to ensure you have a degree in Pharmacy that is acceptable.

  • PEBC Document Evaluation application.

You must pass document evaluation before you qualify to apply for the Evaluating Examination.

 

  • Language Proficiency Requirements
    Language Proficiency Tests are not required by the PEBC. However, Provincial Regulatory Authorities do require these tests.

PEBC recommends you contact the regulatory authority for the province in which you are seeking licensure to receive full information regarding language fluency requirements.

THE PHARMACIST EVALUATING EXAMINATION

Pharmacist Examination is a very important and time-consuming task. It involves gathering information from a large number of sources, analyzing it and then presenting the results in a clear and accurate way.
The pharmacist is the person who has to answer questions about medicines and their properties. This role is very important as it involves a lot of knowledge and experience.

This section will be on question Multiple Answer and Test Questions.

PART 1 – MCQ

 

The PEBC Qualifying Examination for pharmacists has consisted of two components: Part I is the multiple-choice question examination and Part II is a performance assessment. Part II is known as an Objective Structured Clinical Examination (OSCE). It is designed to assess communications/interpersonal skills, the application of knowledge to simulations of commonly encountered patient scenarios and other aspects of professional competence that do not lend well to written examinations. The competencies to be assessed through both the written and practice-based exams are those adopted (or adapted) by all member provinces of the National Association of Pharmacy Regulatory Authorities (NAPRA).

PEBC implemented the PEBC Qualifying Examination for pharmacy technicians, also consisting of a multiple-choice examination (Part I) and performance-based examination (Part II), the Objective Structured Performance Examination (OSPE). The examination will be implemented in provinces as they move forward with regulation of pharmacy technicians. Once licensed in their own province, pharmacy technicians will be integrated into all PEBC examination administration and assessment processes.

COST

Pharmacy is a challenging field and is not as lucrative as other professions. This article will help students and professionals understand the costs associated with studying pharmacy in Canada

 

Fees -Cost for whole process of Registered Pharmacists

Document Evaluation & Examination
Document Evaluation $685 Rupees 41,689.

US Document Evaluation $250 Rupees 1526

Evaluating Examination (2023 fee) $890 Rupees 54,314

Qualifying Examination – Part I (MCQ) $825 Rupees 50,347

Qualifying Examination – Part II (OSCE) $1,855 Rupees 1,13,205

Only if you have money on account with PEBC
Examination Re-scoring (Hand scoring)
Evaluating Examination
$100

Qualifying Examination – Part I (MCQ)
$100

Qualifying Examination – Part II (OSCE)
$200

Examination Rescheduling
Evaluating Examination $43 +HST
Qualifying Examination – Part I (MCQ) $43 +HST
Paid directly to Prometric when rescheduling, if applicable

Miscellaneous
Certificate Replacement $100

Sending Licensing Statement/Good Standing Certificate to Provincial Regulatory Authority $100

ECA Report Request $100

A total of TWO LAKH SIXTY THOUSAND RUPEES FOR REGISTERED PHARMACIST

Fees -Cost for whole process of Registered Pharmacy Technicians

Examination
Qualifying Examination – Part I (MCQ) $560 34,175.36 Indian Rupee

Qualifying Examination – Part II (OSPE) $1,170 71,402.09 Indian Rupee

Only if you have money on account with PEBC
Examination Re-scoring
Qualifying Examination – Part I (MCQ) $100

Qualifying Examination – Part II (OSPE) $200

Examination Rescheduling
Qualifying Examination – Part I (MCQ) $43 +HST
Paid directly to Prometric when rescheduling, if applicable

Miscellaneous
International Evaluation $1,500

Certificate Replacement
$100

Study Tips to become a Pharmacist by clearing your Evaluating Examination PEBC:

What is EE? It is nothing but abbreviation for evaluating examination. It is the basic examination in which every foreign graduates who haven’t completed their degree from Canada. Candidate have to appear in this examination as the name indicates it’s. Evaluating means it will evaluate your degree. This examination will evaluate your degree or your knowledge so that you can appear in the upcoming qualifying examination that is MCQ as well as Osci.

  • work hard
  • study for longer durations
  • make own timetable
  • routine your 24 hours
  • Keep Syllabus copy in front of study table
  • List out topics that are important and in whichever topics you have to study in detail
  • Take  one course and follow it strictly
  • Follow CTC CTMA books for therapeutics
  • Group study in the starting days of your preparation
  • Smart work
  • Daily schedule Consistent Focus

 

 

Tablet Press Machine – Parts Price Manual Manufacturers

Tablet Press

Tablet press machine is used to press dry raw materials into tablet form. Tablet Press are increasingly used in a variety of industries to compress materials like Pharmaceuticals and Life Science Industries, Ayurveda Industries, Silica Industries, Confectionary Industries, Ferrites, Electronics and Defence Industries, Vitamins & Nutraceuticals Industries Salts, Detergents & Metals, API & Bulk Drugs, Food & Confectionary, Nutraceuticals, Ferrites.

Tablet Press Buyers Guide:

Important Specifications of Tablet Press You need to Check Before Buying:

  • Capacity of Torque main motor
  • Water cooling system
  • High Speed
  • Gravity Feeding System
  • Bi-Layer Tablet Attachment
  • Very low Noise level
  • Type of tooling D
  • Rated output (tablets / hour)*
  • Turret speed (rpm)
  • Max. Compaction force-Main (kN)
  • Max. Compaction force-Pre (kN)
  • Biometric Fingerprint lock system
  • Equal Pre & Main compaction of 100 kN
  • Single Tablet Rejection even at highest speed of operation
  • High & Updated Motorised Machine
  • Bi-Layer Tableting with a lot of ease and Separate first Layer Sampling available
  • Zero Clearance,
  • Machine Interlocks with indicating alarms as a Safety Device
  • Compaction Force Control (CFC) system for Auto Weight Control
  • Computer Panel for SCADA
  • 3 – Paddles Force Feeding System
  • Super Thick Upper Guards
  • Sound Reduction & Operator Safety
  • No. of station
  • Max. Tablet diameter (mm)
  • Max. Depth of die fill (mm)
  • Max. Tablet thickness (mm)
  • Upper punch penetration-Main & Pre comp. (mm)
  • Torque direct drive (kW / hp)
  • Power consumption (kW / hp)
  • Power supply
  • Overall dimensions (cm)
  • Net weight (kg)

 

Tablet Press Machine Parts=Principal components of Tablet Press:

• Hopper
• Fill Tray
• Dies
• Upper Punches and Lower Punches
• Turret
• Upper Tracking and Lower Tracking
• Upper Pressure Cam and Lower Pressure

• The Hopper holds the dry materials that will be compressed.
• The Fill Tray distributes the dry materials into the Die bores and pushes tablets into the Ejection Chute.
• The Dies define the size and shape of the powder.
• The Upper Punches and Lower Punches compress the materials within the Dies.
• The Turret houses the Tooling.
• The Upper Tracking and Lower Tracking guide the Tooling.
• The Upper Pressure Cam and Lower Pressure Cam compress the Upper Punches and Lower Punches to create the tablet.

Parts of Tablet Press

• Dont apply too much force to the powder.
• Dont Try to fill the Die with powder by hand.
• Dont insert Tooling that is too big for the machine.
• Properly mount the machine.
• Dont use powders that could explode under pressure.
• Dont use wet or damp material.
Be aware of risk of entanglement and pinch
point due to moving parts.
• Do not operate in a wet environment or with wet hands due to risk of electrical shock or burn.
• Do not operate if any wires are damaged,pinched, or frayed due to risk of electrical shock or burn.
• Keep fingers away from all moving parts.
• Ensure that machine is secure with antivibration feet on the workspace floor.
• Inspect machine before use.
• Check that nuts and bolts are suitably tightened.
• Use this machine only for its intended use as described in this manual.
• Do not modify the machine in any way.
• Turn off and unplug the machine before conducting cleaning and maintenance.

Tablet Press Machine Price

The price of the tablet press is different with different manufacturers. the price depends also on the purpose of the press designed for. the overall cost varies between 4 lakhs to 50 lakhs.

PEBC – Canada Registered Pharmacist EXAM Question Paper with Answers PDF

PEBC Exam paper

Pharmacist Evaluating Examination Sample Questions are given here with answers. The questions are designed to test the knowledge of pharmacists and their ability to apply it in their daily practice. Generally, the exam is divided into two parts, namely a written part and a practical part. The written part consists of multiple choice questions which can be answered using different options provided by the question. On the other hand, the practical OSCE is Part 2 of the examination. The questions here provided are just for practice and based on previous paper or another similar one from the sample paper.

 

BIOMEDICAL SCIENCES

 

  • Folic acid has tetrahydrofolate coenzyme activity which is based on the:
  1. pyrimidine
  2. purine
  3. pyrazine
  4. pteridine
  5. pyridine

 

  • Which of the following releases enkephalins?
  1. Pineal gland
  2. Thyroid gland
  3. Periaqueductal grey matter
  4. Reticular activating system
  5. Pituitary gland

 

  • β-Carotene is the precursor of:
  1. retinoic

 

  • Which of the following statements regarding transcription is correct?
  1. The enzyme responsible for initiating transcription is RNA
  2. The enzyme responsible for initiating transcription is DNA
  3. During transcription, the genetic information contained in the nucleotide sequence of tRNA is translated into a protein
  4. The process of transcription includes the splicing of
  5. Following initiation, the next stage of transcription is

 

  • Which of the following organisms is an obligate intracellular bacteria, making it resistant to cell wall-active antibiotics?
  1. Escherichia coli
  2. Legionella pneumophila
  3. Staphylococcus aureus
  4. Streptococcus pneumoniae
  5. Chlamydophila pneumoniae

 

  • Which of the following blood vessels transports nutrient rich blood from the intestines to the liver?
  1. Hepatic artery
  2. Hepatic portal vein
  3. Great saphenous vein
  4. Inferior vena cava
  5. Superior vena cava

 

  • The blood volume of the average adult is approximately:
  1. 5
  2. 10
  3. 15
  4. 20
  5. 25

 

  • In adults, community-acquired pneumonia caused by which of the following organisms is associated with the highest mortality rate?
  1. Chlamydophila pneumoniae
  2. Mycoplasma pneumoniae
  3. Haemophilus influenzae
  4. Streptococcus pneumoniae
  5. Pneumocystis jirovecii

 

  • Which of the following is the major inhibitory neurotransmitter in the brain?
  1. Gamma-aminobutyric acid
  2. Dopamine
  3. Glutamate
  4. Acetylcholine
  5. Glycine

 

  • Which of the following enzymes catalyzes the synthesis of DNA from viral RNA?
  1. Reverse transcriptase
  2. DNA polymerase
  3. RNA polymerase
  4. Endonuclease
  5. Aminoacyl-tRNA synthetase

 

  • Of the essential transition metal ions found in the human body, the one present at highest overall concentration is:

 

 

  • The optic disc is also called the:
  1. blind
  2. macula

 

  • If systemic blood pressure decreases, which of the following would occur to help return blood pressure to normal?
  1. Increased urine production
  2. Increased acetylcholine release
  3. Increased aldosterone secretion
  4. Increased diameter of systemic arterioles
  5. Increased erythropoietin production

 

  • Which of the following muscle groups are innervated by the sciatic nerve?
  1. Calf muscles
  2. Deep back muscles
  3. Shoulder muscles
  4. Quadriceps femoris muscles
  5. Abdominal muscles

 

  • Which of the following does NOT empty its contents into the gastrointestinal tract?
  1. Liver
  2. Pancreas
  3. Spleen
  4. Submandibular gland
  5. Appendix

 

  • Achieving a high level of herd immunity is an important public health strategy because it:
  1. reduces immunization costs in
  2. enhances individual immunologic
  3. facilitates animal
  4. protects people who cannot be
  5. requires fewer booster

 

PHARMACEUTICAL SCIENCES

 

  • All of the following statements concerning the lyophilization of a parenteral product are correct,

EXCEPT:

  1. there is minimal loss of activity in heat labile
  2. the liquid must be frozen to below the eutectic
  3. the solute usually forms an amorphous
  4. the eutectic temperature is the freezing point of the drug
  5. water is removed from the frozen mixture by

 

  • Dopamine is useful in the treatment of cardiogenic shock because it:
  1. selectively dilates renal and mesenteric vascular
  2. does not induce peripheral
  3. decreases the force of myocardial
  4. delays the atrioventricular (AV) conduction
  5. prolongs the QT interval on the

 

  • Concentration of a drug in breast milk exceeds that in plasma, if the drug:
  1. is
  2. is protein
  3. is acidic but not protein
  4. has a small volume of
  5. has a large volume of

 

  • Drug A is administered by continuous IV infusion at a rate of 2 mg/min. It has an average half-life of
    • h and a volume of distribution of 150 L in an average 70 kg patient. Using this information, what is the steady-state concentration of Drug A in plasma?
  1. 5 mg/L
  2. 7 mg/L
  3. 1 mg/L
  4. 4 mg/L
  5. 7 mg/L

 

21

Valproic acid is metabolized by aliphatic hydroxylation to the above two structures. The relationship between the two metabolites illustrates the concept of:

  1. conformational
  2. structural
  3. geometric
  4. optical

 

 

  • Which of the following medications induces an isoform of cytochrome P450?
  1. Carbamazepine
  2. Clarithromycin
  3. Amiodarone
  4. Metronidazole
  5. Bosentan

 

  • Diazepam Injection U.S.P Diazepam 5 mg/ml

Ethanol 10%

Propylene glycol 40%

Benzyl alcohol 1.5%

Water for Injection qs 100%

In the formulation given above, propylene glycol functions as a(n):

 

  • Which of the following directly influences the in vitro physical stability of an oil-in-water emulsion in which the drug is incorporated in the dispersed phase?
  1. Amount of preservative added
  2. Molecular weight of the drug
  3. Solubility of the emulsifier in water
  4. Particle size of the internal phase
  5. Type of suspending agent used

 

  • Abatacept acts by:
  1. stimulating adenosine
  2. binding to MHC Class II on B
  3. inhibiting B cell
  4. activating T cell
  5. binding CD80/86 on antigen-presenting

 

  • With respect to bioequivalence, the parameter “Cmax” is:
  1. affected by the extent of absorption
  2. affected by the rate of absorption
  3. affected by neither rate nor extent of
  4. affected by both rate and extent of
  5. the only significant

 

27

The above structures are related to one another as:

  1. positional (structural)

 

  • Five subjects given a single intravenous dose of a drug have the following elimination half-lives: 3, 9, 6, 5, and 4 h (hours). The mean half-life is:
  1. 4
  2. 5
  3. 5.4 h.
  4. 5.8 h.
  5. 6 h.

 

  • Reasons for using coatings on tablets include all of the following, EXCEPT:
  1. to mask the taste of the
  2. to mask the odor of the
  3. to improve the appearance of the
  4. to increase the drug’s release
  5. to protect the drug from stomach

 

  • Which of the following terms indicates a loss of moisture?
  1. Deliquescence
  2. Efflorescence
  3. Hygroscopicity
  4. Polymorphism
  5. Condensation

 

 

  • Which of the following statements is FALSE regarding tablet formulation?
  1. Diluents are fillers to add bulk to the
  2. Lubricants help the patient to swallow the tablet more
  3. Binding agents may be added dry or in
  4. Disintegrants draw water into the tablet causing it to
  5. Glidants promote the flow of materials during

 

  • Factors that determine bioequivalence of two brands of a drug include the:
  1. taste of the
  2. physical appearance of the
  3. pharmacokinetic parameters of the
  4. cost of the
  5. package size of the

 

 

  • The total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10 mL/min. This is most likely explained by the fact that the drug:
  1. is extensively
  2. accumulates in patients with moderate renal failure
  3. undergoes significant entero-hepatic
  4. is not bound to plasma
  5. is concentrated in adipose

 

  • The major pathway for the biotransformation of the following compound is by hydrolysis. Identify the site which would be most susceptible to
  1. A
  2. B
  3. C
  4. D
  5. E

 

  • Imatinib is an anticancer agent used in the treatment of chronic myelogenous leukemia that acts by inhibiting the activity of:
  1. tyrosine kinase of Bcr-Abl.
  2. tyrosine kinase of HER-2.
  3. tyrosine kinase of
  4. histone
  5. serine/threonine kinase

 

  • Which of the following diuretics is used to block the Na+-H+ exchange system of the renal tubule?
  1. Furosemide
  2. Hydrochlorothiazide
  3. Spironolactone
  4. Acetazolamide
  5. Amiloride

 

  • Atropine poisoning can be recognized by all of the following signs or symptoms, EXCEPT:
  1. dry
  2. flushed
  3. delirium and restlessness.

 

  • The organophosphates commonly found in insecticides are thought to act by which of the following mechanisms?
  1. Combining with acetylcholine
  2. Potentiating the action of acetylcholinesterase
  3. Forming a very stable complex with acetylcholinesterase
  4. Reacting at the cholinergic receptor
  5. Preventing the release of acetylcholine from the nerve ending

 

  • Which of the following is a selective adrenergic beta1-blocker with endothelium-dependent vasodilating properties?
  1. Nebivolol
  2. Metoprolol
  3. Acebutolol
  4. Nadolol
  5. Carvedilol

 

  • Which of the following statements is correct regarding the use of monoclonal antibody drug therapies?
  1. Flu-like symptoms commonly occur at the start of
  2. T cells are stimulated and will initiate a host rejection
  3. Adalimumab is a murine-derived immunoglobulin monoclonal antibody
  4. Use of chimeric monoclonal antibodies is associated with increased
  5. Use of Fc fragments avoids raising an immune response against the FAB

 

  • In some parenteral formulations, sodium metabisulphite is included as:
  1. an
  2. a
  3. a
  4. a
  5. an

 

  • The carbonic anhydrase inhibitor dorzolamide is structurally classified as a:

 

  • Which of the following statements is FALSE regarding virus vectors used in the production of biotechnology drugs?
  1. Viruses can be introduced by
  2. Viruses can be generated by an infected production cell
  3. The most frequent source of virus introduction is the growth
  4. Viruses can be inactivated by physical or chemical treatment of the
  5. There is a trend toward using better-defined growth media in which serum levels are significantly reduced.

 

  • Which of the following excipients is NOT commonly found in biotechnology formulations?
  1. Albumin
  2. Lysine
  3. Tween 20
  4. Saline
  5. Phosphate

 

  • An angiotensin-converting enzyme (ACE) inhibitor for which both renal elimination and metabolism are important in the elimination of the drug and its active metabolites is:

 

  • Once daily dosing of aminoglycosides is effective due to:
  1. prolonged residence of the antibiotic in the
  2. post-antimicrobial
  3. enhanced tissue
  4. reduced renal
  5. higher peak-trough

 

  • How much NaCl is required to make 100 mL of isotonic 5% phenylephrine HCl solution? (NaCl equivalent of phenylephrine HCl is 0.32)
  1. 100 mg
  2. 300 mg
  3. 500 mg
  4. 740 mg
  5. 900 mg

 

  • Which of the following nonparenteral routes of administration yields the best bioavailability of biotechnology protein drugs?
  1. Oral
  2. Rectal
  3. Ocular
  4. Pulmonary
  5. Transdermal

 

  • Theoretically, the shelf life of a pharmaceutical tablet preparation is best measured by a change in which of the following?
  1. Permeability of the drug
  2. Dissolution of the drug
  3. Strength of the drug
  4. Solubility of the drug
  5. Partitioning of the drug

 

  • A drug that is considered to be low clearance and is metabolized entirely by the liver is sensitive to changes in:
  1. drug binding to plasma
  2. bile
  3. hepatic blood
  4. renal blood
  5. p-glycoprotein transport

 

  • Which of the following statements is correct about transdermal drug administration?
  1. Most drugs can permeate the skin and enter the systemic
  2. Transdermal absorption achieves a fast onset of drug
  3. The skin is tolerant to most drugs and chemicals in transdermal delivery
  4. Transdermal administration produces minimal variations in drug
  5. Hair follicles are a determinant in limiting transdermal drug

 

  • Two drugs (Drug A and Drug B) were administered at a dose of 10 mg/kg to two subjects. Drug A was administered intravenously and Drug B was administered orally. Plasma samples were collected

and concentrations of both drugs were measured. A semilog plot of concentration vs. time is shown below. The concentration of Drug A is represented by the solid line and Drug B by the dashed line.

 

 

 

 

Which of the following statements is correct?

  1. The absorption rate constants for Drug A and Drug B can be estimated from the
  2. Drug B has a lower clearance than Drug
  3. Drug A has a larger distribution volume than Drug
  4. Drug B has a higher plasma protein binding than Drug
  5. The volume of distribution for Drug A can be estimated from the

 

  • Which of the following drugs is an antagonist at the central presynaptic alpha2-adrenergic receptors?
  1. Clonidine
  2. Terazosin
  3. Mirtazapine
  4. Risperidone
  5. Venlafaxine

 

  • A monoclonal antibody was tested in patients using the following dose ranges and resulted in the following t1/2 values:

Dose                  Half-life

0.2 mg/kg           2 days

  • mg/kg 8 days
  • mg/kg 18 days
  • mg/kg 18 days

5 mg/kg            18 days

What is the reason for the dose-dependent t1/2? The biologic drug:

  1. eliminates primarily by the lymphatic system at lower
  2. eliminates primarily by the liver resulting in nonlinear
  3. eliminates by
  4. distributes rapidly to peripheral organs at lower
  5. exhibits target-mediated drug

 

  • Pravastatin inhibits:
  1. PCSK9
  2. lipoprotein
  3. vascular oxidative
  4. scavenger receptor
  5. HDL

 

  • In a manufacturing setting, which of the following methods is the most appropriate to use for sterilization of plastic (PVC) tubing?
  1. Dry heat
  2. Steam autoclave
  3. Ionizing radiation
  4. Ethylene oxide gas
  5. Filtration

 

  • What is the first process used when evaluating the integrity of a recombinant protein after each purification step?
  1. ELISA
  2. Quantitative PCR
  3. Peptide mapping
  4. SDS-polyacrylamide gel electrophoresis
  5. Amino acid sequencing

 

  • Which of the following types of neurotransmitter receptors is most responsible for the

decreased risk of extrapyramidal side effects observed with some second generation antipsychotics relative to first generation antipsychotics?

  1. Serotonergic
  2. Histaminergic
  3. Muscarinic
  4. Noradrenergic
  5. Alpha-adrenergic

 

  • In tablets made from wet granulation processing, which of the following substances is commonly included as a lubricant?
  1. Lactose
  2. Potato starch
  3. Croscarmellose
  4. Dicalcium phosphate
  5. Sodium lauryl sulfate

 

  • Permeation enhancers increase drug absorption from buccal dosage forms by which of the following mechanisms?
  1. Decreasing drug solubility
  2. Extracting oral mucosal lipids
  3. Disrupting saliva secretion
  4. Increasing drug particle size
  5. Prolonging oral retention

 

  • Disintegration of a compressed tablet is primarily dependent upon which of the following properties of the tablet?
  1. Size
  2. Shape
  3. Hardness
  4. Coating
  5. Stability

 

PHARMACY PRACTICE – Clinical Sciences

 

  • At typical dosing, which of the following antidepressant medications is associated with the highest incidence of nausea?
  1. Sertraline
  2. Fluoxetine
  3. Duloxetine
  4. Escitalopram
  5. Desvenlafaxine

 

  • Which of the following statements is correct regarding the use of fluoroquinolones?
  1. Fluoroquinolones can cause blood glucose alterations in elderly patients who take oral antihyperglycemic
  2. Healthy women with acute uncomplicated cystitis should be treated for a minimum of 7 days with a fluoroquinolone.
  3. Therapeutic drug monitoring is recommended with prolonged fluoroquinolone therapy, to avoid ototoxicity.
  4. In the case of treatment failure, another fluoroquinolone should be tried before switching to a different antibiotic
  5. All fluoroquinolones have equal efficacy when used to treat patients with community-acquired pneumonia.

 

QUESTIONS 64 TO 65 INCLUSIVE REFER TO THE FOLLOWING:

SM is a 34 year old female who, while vacationing in Mexico, began prophylactic treatment for travellers’ diarrhea. Shortly thereafter she complained of a feeling of fullness in her ears, black stools and a black tongue. SM’s previous history includes an allergy to sulfonamides.

 

  • Which of the following drugs could be the cause of SM’s complaints?
  1. Bismuth subsalicylate
  2. Cotrimoxazole (sulfamethoxazole/trimethoprim)
  3. Doxycycline
  4. Amoxicillin
  5. Loperamide

 

  • An organism commonly implicated in the cause of travellers’ diarrhea is:
  1. Bacteroides fragilis.
  2. Escherichia coli.
  3. Clostridium difficile.
  4. Listeria monocytogenes.
  5. Pseudomonas aeruginosa.

 

 

************

 

  • Which of the following medications requires monitoring for the adverse effect of dyslipidemia?
  1. Ciprofloxacin
  2. Allopurinol
  3. Isotretinoin
  4. Ramipril
  5. Raloxifene

 

  • The mother of a 6 year old child presents to the pharmacist with a written prescription for amoxicillin that was ordered by the physician three days earlier. She states that her child was diagnosed wit otitis media and the symptoms have remained the same over the past three Which of the following is the most appropriate pharmacist response?
  1. Fill the prescription as written
  2. Refuse to fill the prescription as the antibiotic order is no longer current
  3. Indicate a need to contact the prescriber before filling the prescription at this time
  4. Fill the prescription for a quantity that is the ordered amount less three days’ supply
  5. Explain that, at this late date, antibiotic therapy will likely be ineffective for the child

 

  • RF is an 80 year old female who developed CDAD (Clostridium difficile-associated diarrhea) after recent treatment of a urinary tract infection with ciprofloxacin. She is admitted to hospital with profound diarrhea (eight watery bowel movements per day) and fever (39.5º C). Based on her symptoms, which of the following is the most appropriate therapy choice for her?
  1. Oral metronidazole
  2. Intravenous metronidazole
  3. Oral cholestyramine
  4. Oral vancomycin
  5. Intravenous vancomycin

 

  • CC, a 72 year old female, complains to the pharmacist that her stomach has been bothering her recently. Current medications include: levothyroxine 100 mcg po daily (x 30 years), acetaminophen 500 mg po qid (x 5 months), atorvastatin 40 mg po at bedtime (x 4 years), ibuprofen 400 mg po tid prn joint pain (x 2 months), and zopiclone 3.75 mg po at bedtime prn (x 3 months). Based on CC’s current symptoms, which of the following drug therapy problems best describes CC’s current situation?
  1. Too high a dosage of atorvastatin
  2. Too high a dosage of zopiclone
  3. Need for cytoprotection with ibuprofen
  4. Drug interaction between atorvastatin and zopiclone
  5. Too low a dosage of levothyroxine

 

  • A 27 year old patient presents to a community pharmacy for the first time and tells the pharmacist that he experienced an allergy to a penicillin product as a child. His symptoms included hives, wheezing and facial swelling, which resulted in hospitalized Which of the following is the most important reason for a community pharmacist to document this type of information in a patient’s medication profile record?
  1. To provide drug allergy information to the patient’s insurance
  2. To encourage the patient to fill future prescriptions at this
  3. To advertise relevant pharmacy products or services to appropriate
  4. To enhance continuity of patient care regardless of the
  5. To provide a record of cognitive services for insurance

 

 

QUESTIONS 71 TO 72 INCLUSIVE REFER TO THE FOLLOWING:

 

TK is a 63 year old male with chronic kidney disease (CrCl = 29 mL/min/1.73m2) and gout. He experienced his last gout attack about two months ago. Today his toe is extremely painful, hot, red, and swollen. At a walk-in clinic, he receives a prescription for naproxen 500 mg po bid for five days. TK’ s other current medication is pravastatin 20 mg po at bedtime.

 

  • What drug therapy problem should the pharmacist identify for TK?
  1. Naproxen is inferior to indomethacin for the treatment of acute
  2. The duration of naproxen treatment is too
  3. Naproxen should be avoided in patients taking
  4. Naproxen should be avoided in patients with renal
  5. The frequency of naproxen dosing is too

 

  • Following successful resolution of the acute episode, TK’s physician decides that he should initiate allopurinol. TK should be advised to:
  1. limit fluid
  2. take medication on an empty
  3. use precautions to avoid
  4. report any skin rash or itching to the
  5. avoid dairy products or multivitamins within 2 hours of

**********

 

  • All of the following have been implicated in causing toxic nephropathy, EXCEPT:

 

  • In the treatment of a patient who has a solid tumour, which of the following side effects typically occurs one to two weeks after chemotherapy?
  1. Neuropathy
  2. Cardiotoxicity
  3. Neutropenia
  4. Emesis
  5. Nephrotoxicity

 

  • Lactose intolerance is classified as a(n):
  1. enzyme
  2. mineral
  3. transporter
  4. vitamin

 

  • A community pharmacist conducts a medication review for a 67 year old patient who has a 20-year history of COPD, diabetes and The patient’s current medications include the following:

Aclidinium 400 mcg inhaler, one inhalation bid

Budesonide 200 mcg/formoterol 6 mcg Turbuhaler®, 2 inhalations bid Salbutamol 100 mcg MDI, 2 inhalations qid

Sitagliptin100 mg, one tablet po daily Metformin 500 mg, one tablet po tid

Venlafaxine ER 150 mg, one capsule po at bedtime

Which of the following drug therapy problems should be identified for this patient?

  1. Taking too high a dosage of aclidinium
  2. Taking too high a dosage of metformin
  3. Inappropriate dosing time for venlafaxine
  4. Drug interaction between sitagliptin and metformin
  5. Duplication of therapy with salbutamol and formoterol

 

  • Which of the following is characterized as an autoimmune disorder?
  1. Alzheimer disease
  2. Systemic lupus erythematosus
  3. Osteoarthritis
  4. Parkinson disease
  5. Paget disease

 

  • A pregnant female presents with a prescription for an antibiotic for treatment of a urinary tract infection. She tells the pharmacist that she doesn’t know why the doctor gave her the medication, because she isn’t experiencing any symptoms. Her presentation is consistent with which of the following diagnoses?
  1. Cystitis
  2. Septicemia
  3. Urinary retention
  4. Pyelonephritis
  5. Asymptomatic bacteriuria

 

  • A community pharmacist would like to begin a diabetic education program for local patients newly diagnosed with type 2 diabetes mellitus. Beneficial information for this group includes all of the following EXCEPT:
  1. strategies to minimize cardiac risk
  2. the facts on diabetes and its
  3. the role of blood glucose
  4. appropriate dietary
  5. the technique for the mixing of

 

  • Which of the following would be the most appropriate treatment for moderate to severe atopic dermatitis in an 8 year old child?
  1. Urea 20% cream
  2. Tacrolimus 0.03% cream
  3. Pimecrolimus 1% cream
  4. Betamethasone dipropionate 0.05% ointment
  5. Clobetasone propionate 0.05% cream

 

  • Which of the following is a normal host defence that helps to prevent pneumonia?
  1. Low sputum pH
  2. Aspiration
  3. Thick, tenacious sputum
  4. Neutropenia
  5. Epiglottal closure

 

  • Tadalafil is preferred over sildenafil in which of the following patient situations?
  1. After using sublingual nitroglycerin
  2. After eating a high-fat meal
  3. If receiving hemodialysis
  4. If taking testosterone supplementation
  5. For males over the age of 60 years

 

  • Which of the following vitamins is found at reduced levels in cigarette smokers compared to nonsmokers?
  1. Vitamin A
  2. Vitamin B12
  3. Vitamin C
  4. Vitamin D
  5. Vitamin K

 

  • Which of the following is a reasonable goal of therapy for a patient with active inflammatory bowel disease?
  1. Prevent infection
  2. Prevent mortality
  3. Maintain quality of life
  4. Achieve endoscopic remission
  5. Limit the number of colectomies

 

  • BC is a 25 year old female with depression who has had an adequate trial with each of sertraline and escitalopram. She has tolerated the medications but has only achieved a partial response to escitalopram 20 mg po once Which of the following is the most appropriate next step for BC?
  1. Increase escitalopram to 40 mg po once daily
  2. Add diazepam 5 mg po once daily to escitalopram
  3. Add aripiprazole 2 mg po once daily to escitalopram
  4. Stop escitalopram and start fluoxetine 20 mg po once daily
  5. Stop escitalopram and start venlafaxine XR 150 mg po once daily

 

PHARMACY PRACTICE – Professional Practice Skills Questions

 

  • Which of the following is NOT a benefit of performing medication reconciliation activities in a hospital setting?
  1. Reduction of medication errors
  2. Reduction of inventory pilferage
  3. Reduction of preventable adverse effects
  4. Assessment of patient adherence to therapy
  5. Enhanced accuracy of patient allergy information

 

  • The web site of which of the following would be most appropriate to consult in order to determine whether there are any safety alerts associated with a prescription drug product?
  1. Canadian Agency for Drugs and Technologies in Health
  2. Health Canada
  3. Institute for Safe Medication Practices
  4. Canadian Patient Safety Institute
  5. Canadian Institute for Health Information

 

  • In dispensing, the Latin abbreviation for “before meals” is:

 

  • In dispensing, the English meaning for the Latin phrase “ex aqua” is:
  1. with or in
  2. extracellular
  3. exact
  4. soluble in
  5. out of

 

  • Aerosol OT (AOT) is used in veterinary medicine as a laxative. If 250 g of AOT is dissolved in 1 000 mL of glycerin (density of glycerin is 1.25 g/mL), the concentration of AOT in the solution is:
  1. 12.5% w/w.
  2. 16.7% w/w.
  3. 20% w/w.
  4. 23.8% w/w.
  5. 25% w/w.

 

  • Appropriate quality control procedures to ensure product and patient safety in the pharmacy do NOT include which of the following?
  1. Adhering to guidelines for cold chain management
  2. Maintaining a regular cleaning schedule for dispensary surfaces
  3. Cleaning counting trays and automated counting machines regularly
  4. Using TALLman lettering on all prescription labels
  5. Regulating the pharmacy’s indoor climate where medications are stored

 

  • Which of the following statements is correct regarding the MedlinePlus web site for drug information? The service:
  1. provides a compilation of clinical practice guidelines for health care
  2. provides systematic reviews that are based solely on evidence from primary
  3. has an emphasis on providing patient/consumer information on a wide variety of health
  4. is limited by its availability only through paid subscription by health care
  5. is limited by a lag to publication and updating of patient therapy-related

 

  • The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine Appropriate information to provide to the patient includes which of the following?
  1. If the sumatriptan does not relieve the headache within four hours, ergotamine may be
  2. If no relief is achieved in two hours, sumatriptan may be
  3. If the headache is relieved but another headache occurs eight hours later, sumatriptan may be used for the second
  4. The maximum dosage in any 24-hour period is six
  5. If relief is not achieved, no other medication can be used for 24

 

  • Which of the following medications requires an auxiliary label regarding avoiding the consumption of grapefruit or grapefruit juice?
  1. Felodipine
  2. Amlodipine
  3. Levetiracetam
  4. Divalproex
  5. Gabapentin

 

  • The recommended pediatric dosage for azithromycin therapy is 12 mg/kg po once daily on Days 1 through 5. For a child weighing 8.3 kg, calculate the total volume needed for the total course of treatment, if a product supplying 200 mg/5 mL is supplied for this
  1. 5 mL
  2. 15 mL
  3. 25 mL
  4. 5 mL
  5. 50 mL

 

  • A pharmacist is making a presentation on medication adherence to a group of clients. Which of the following would be the most appropriate indicator of the effectiveness of the presentation for these clients?
  1. Increase in fill quantity for each prescription refill
  2. Reduced number of prescriptions filled per month
  3. Increase in number of nonprescription medications used
  4. Reduced number of prescription refill dates per month
  5. Prescription refill dates closer to expected fill intervals

 

  • Rx Timolol 0.25 % drops Mitte : 15 mL

Sig: gtt. i o.d. bid

On the prescription label the instructions to the patient should read:

  1. apply one drop into both eyes twice
  2. instil one drop into the left eye twice
  3. instil one drop into the right eye twice
  4. shake well and instil one drop into the left eye twice
  5. shake well and instil one drop into the right ear twice

 

 

  • According to ISMP guidelines, which of the following medication orders contains a dangerous abbreviation or dosing designation?
  1. Insulin NPH 10 units subcut at bedtime
  2. Oxycodone CR 40 mg po q12h
  3. Gliclazide 80 mg po bid
  4. MTX 7.5 mg po weekly
  5. Levothyroxine 88 mcg po daily

 

  • Which of the following statements is correct regarding Tylenol Elixir With Codeine® (each 5 ml contains acetaminophen 160 mg and codeine 8 mg)?
  1. It requires a written order from an authorized
  2. It is an example of a legally exempted codeine
  3. Sale for self-medication use must involve a
  4. It is regulated under the Benzodiazepines and Other Targeted Substances
  5. Authorized prescribers include

 

  • A physician wants to switch a terminally-ill patient from slow release morphine sulfate tablets, 15 mg tablets. If a morphine sulfate solution containing 5 mg per mL is prescribed q4h, what volume should be dispensed for a 20 day supply to provide the same pain relief as the tablet regimen?
  1. 20 mL
  2. 60 mL
  3. 80 mL
  4. 100 mL
  5. 120 mL

 

  • A biological safety cabinet is required when preparing a parenteral formulation of:
  1. magnesium

 

  • Which of the following drug orders is incomplete and requires follow-up with the prescriber?
  1. Zithromax Z-Pak® (azithromycin 250 mg), 2 tabs po on day 1 and 1 tab po on days 2-5.
  2. Flonase® (fluticasone) 100 mcg spray, 1 or 2 sprays in each nostril bid x 1 bottle
  3. Actonel® (risedronate), 35 mg po once weekly x 12 tabs
  4. Cozaar® (losartan), 50 mg po bid x 1 month
  5. Zocor® (simvastatin), 1 tab po hs for 3 months

 

  • JN, a 17 year old male with a highly resistant form of testicular cancer, is in hospital for treatment. He is an intelligent, articulate young His parents are insisting that the physician treat him with the latest experimental therapy, but JN does not want to undergo the treatment. If the physician goes ahead and gives the experimental therapy what ethical principle will have been violated the most?
  1. Confidentiality
  2. Nonmaleficence
  3. Justice
  4. Veracity
  5. Autonomy

 

 

  • Which of the following statements is correct regarding hypothesis testing?
  1. A type I error frequently occurs when sample sizes are
  2. A type II error is more serious than a type I
  3. Small p-values suggest that the null hypothesis is likely to be
  4. The larger the p-value, the more likely the null hypothesis is
  5. P-value is the probability of wrongly rejecting the null hypothesis if it is in fact

 

 

  • An adequately powered, randomized controlled trial conducted over two years demonstrated that the primary outcome (a serious cardiovascular event) occurred in 15% of the patients who received the new drug, whereas the primary outcome occurred in 25% of the patients who received a placebo. The relative risk reduction achieved with the new drug is:
  1. 10%.
  2. 15%.
  3. 25%.
  4. 40%.
  5. 50%.

 

  • In an adequately powered, randomized controlled trial conducted over three years, a specific serious side effect (i.e., reduction in leukocytes) with conventional therapy is seen in 0.5% of the study sample. In patients who receive a newly discovered drug, only 0.45% experience the same side effect. Based on these results, the minimum number of patients that would have to receive the new drug for three years to statistically demonstrate the prevention of one episode of this side effect in at least one patient is:
  1. 15.
  2. 20.
  3. 150.
  4. 200.
  5. 2000.

 

  • In a study comparing two drug treatment regimens, a type II error occurs when:
  1. the statistical conclusion is that there is a difference between the two treatment regimens when a difference does not actually
  2. the statistical conclusion is that there is no difference between the two treatment regimens when a difference actually does
  3. the p level is > 05.
  4. the drug treatments studied are not appropriate comparators for the
  5. the exclusion criteria are too

 

  • A pharmacist has received information regarding a new drug to treat hypertension. The information is based on a two-month, placebo controlled, randomized study of 1000 adults that showed a statistically significant average decrease in systolic pressure from 160 mm Hg to 141 mm Hg and in diastolic pressure from 98 mm Hg to 86 mm Hg. The most common adverse reactions were stomach upset and dizziness. Which of the following is the most significant limitation of this study?
  1. The study size was too small to assess
  2. The patients did not achieve guideline targets for
  3. Blood pressure is a surrogate
  4. Long term safety and efficacy were not
  5. Placebo is not an appropriate

 

  • Part G of Canada’s Food and Drug Regulations deals with which of the following?
  1. Vitamins and minerals
  2. Pharmaceuticals
  3. Controlled Drugs
  4. Benzodiazepines and Targeted Substances
  5. Narcotic Preparations

 

  • Which of the following is a significant barrier perceived by physicians, that impedes effective pharmacist-physician collaboration in the provision of patient care?
  1. Provision of patient-specific counselling by pharmacists
  2. Lack of adequate education and training of pharmacists
  3. Lack of pharmacist follow up in assessing patient outcomes
  4. Increased patient demands for more frequent medical appointments
  5. Interruption of physician workflow due to pharmacist communications

 

  • Which of the following statements regarding a disruption in the cold chain for vaccines is correct?
  1. Vaccines exposed to temperatures above the recommended range can have an increase in potency and should not be administered to any
  2. Vaccines exposed to temperatures below the recommended range should be labelled “do not use” and kept at room temperature until their integrity is
  3. Inactivated vaccines are more likely than live attenuated vaccines to have a shortened half-life when exposed to high temperatures (up to 37º C).
  4. Diluents of vaccines that have been frozen can be used as they do not contain any active ingredients.
  5. Vaccines containing an aluminum adjuvant experience a permanent loss of potency when subjected to

 

 

Questions from BEHAVIOURAL, SOCIAL AND ADMINISTRATIVE PHARMACY SCIENCES

 

 

  • In deciding what drugs are appropriate for its formulary, the hospital must consider a drug’s efficacy, associated workload, and acquisition Several new antifungal IV drugs (drug A, drug B, drug C, and drug D), all with equal efficacy, have recently become available. Currently the hospital stocks drug E, which has been available for several years. Data for the medications is as follows:

 

Drug Cost/Day Dosing Frequency Treatment Duration (days)
A $2.50 qid 14
B $2.25 once daily 14
C $5.00 bid 7
D $2.25 bid 7
E $2.25 qid 7

The most appropriate choice for the hospital is:

  1. Drug
  2. Drug
  3. Drug
  4. Drug
  5. Drug

 

  • Which financial statement could be used to determine the total value of prescription drug sales for a pharmacy during the course of a year?
  1. Balance sheet
  2. Statement of investments
  3. Statement of changes in financial position
  4. Income statement
  5. Statement of equity

 

  • The standard of universal access to government insured health care in Canada is mandated by:
  1. the Canada Health
  2. individual provinces and
  3. Health Canada’s Health Environment and Consumer Safety
  4. Canadian Agency for Drugs and Technologies in Health
  5. Public Health Agency of

 

  • Which of the following responsibilities can be appropriately delegated to a non-pharmacist manager of a community pharmacy?
  1. Purchasing narcotic drugs
  2. Selecting clinical decision software for the dispensary computer
  3. Coordinating staff scheduling
  4. Supervising pharmacy technicians
  5. Determining workflow for the pharmacy’s professional services

 

  • Academic detailing by pharmacists provides a service to physicians by:
  1. educating on improved prescription
  2. advising on optimal patient interviewing
  3. recommending strategies to avoid medication
  4. providing current information on best prescribing
  5. promoting the use of physician samples given to

 

  • A role of The National Association of Pharmacy Regulatory Authorities is to:
  1. audit the financial performance of provincial pharmacy licensing
  2. promote harmonization of pharmacy practice standards across
  3. establish a unified lobby voice for pharmacists from all types of practice
  4. provide mechanisms for the public to file complaints about pharmacy care
  5. accredit the pharmacy programs at Canadian universities

 

  • The term ‘perspective’ in the context of a pharmacoeconomic study refers to the:
  1. source of funding for conducting the pharmacoeconomic
  2. approach the researcher takes to analyze the research
  3. approach the researcher uses to limit confounding
  4. stakeholder whose interest is most represented in the study’s
  5. method used to facilitate communication of the study results in a journal

 

  • Which of the following would be the most effective method to prevent “inventory shrinkage” due to internal theft within a pharmacy?
  1. Assigning the responsibility of ordering and receiving of inventory to one
  2. Implementing an employee bag check program at the end of
  3. Hiring a uniformed security guard to monitor the pharmacy
  4. Offering incentives such as employee discounts on
  5. Installing mirrors and security cameras strategically throughout the

 

  • In the context of a pharmacy business, which of the following groups represent a market niche, rather than a market segment?
  1. Women
  2. The elderly population
  3. Children with asthma
  4. High-income earners
  5. Parents of young children

 

  • An identical screening test for a disease is used in two Communities (A and B), but the proportion of false positive results among those who test positive in Community A is lower than those who test positive in Community B. What is the most likely explanation for this finding?
  1. The specificity of the test is lower in Community
  2. The specificity of the test is higher in Community
  3. The prevalence of disease is lower in Community
  4. The prevalence of disease is higher in Community
  5. It is not possible to explain the difference between Community A and

 

  • “Medically necessary” services are established in Canada by the:
  1. provincial
  2. provincial drug
  3. Canadian Medical
  4. federal
  5. Royal College of Physicians and Surgeons of

 

  • Including a cost assessment in the protocol for a randomized, controlled clinical trial is called a:
  1. cost-benefit
  2. cost-minimization
  3. cost-effectiveness
  4. cost-efficacy analysis.
  5. cost-utility

 

  • The best study design to assess intermittent or transient drug exposures is a:
  1. case-control
  2. retrospective cohort
  3. randomized control
  4. case-crossover
  5. cross-sectional

 

  • Customer loyalty should be important to a pharmacy manager because it:
  1. reduces the amount of time that pharmacists must spend with
  2. generates a stream of high revenue from an identifiable customer
  3. helps the pharmacy staff to greet customers by their first
  4. protects the pharmacy manager from liability claims arising from dispensing
  5. is costly to attract new

There are few missing parts. Pls Download the PDF of Canada Registered Pharmacist Exam Question Paper

Canada Pharmacist Exam Question and Answers

Answers to above Questions

 

1. (d) 26. (d) 51. (c) 76. (e) 101. (b)
2. (c) 27. (c) 52. (e) 77. (b) 102. (e)
3. (a) 28. (c) 53. (c) 78. (e) 103. (e)
4. (a) 29. (d) 54. (e) 79. (e) 104. (e)
5. (e) 30. (b) 55. (c) 80. (b) 105. (d)
6. (b) 31. (b) 56. (d) 81. (e) 106. (e)
7. (a) 32. (c) 57. (d) 82. (b) 107. (b)
8. (d) 33. (a) 58. (c) 83. (c) 108. (d)
9. (a) 34. (c) 59. (e) 84. (d) 109. (c)
10. (a) 35. (a) 60. (b) 85. (c) 110. (e)
11. (c) 36. (d) 61. (c) 86. (b) 111. (e)
12. (a) 37. (e) 62. (a) 87. (b) 112. (d)
13. (c) 38. (c) 63. (a) 88. (a) 113. (d)
14. (a) 39. (a) 64. (a) 89. (a) 114. (a)
15. (c) 40. (a) 65. (b) 90. (b) 115. (c)
16. (d) 41. (a) 66. (c) 91. (d) 116. (d)
17. (d) 42. (c) 67. (a) 92. (c) 117. (b)
18. (a) 43. (c) 68. (d) 93. (c) 118. (d)
19. (a) 44. (c) 69. (c) 94. (a) 119. (b)
20. (b) 45. (b) 70. (d) 95. (a) 120. (c)
21. (b) 46. (b) 71. (d) 96. (e) 121. (d)
22. (a) 47. (d) 72. (d) 97. (c) 122. (a)
23. (c) 48. (d) 73. (e) 98. (d) 123. (d)
24. (d) 49. (c) 74. (c) 99. (a) 124. (d)
25. (e) 50. (a) 75. (b) 100.(e) 125. (e)

 

150-Hyderabad Pharmaceutical Companies

Hyderabad:

  1. Anus Laboratories Ltd
  2. Aptuit Laraus
  3. AR Life Sciences Pvt Ltd
  4. ATS GeneTech Pvt Ltd
  5. Aurobindo Pharma
  6. Aveta Lifesciences Pvt.Ltd.
  7. Avon Organics Ltd
  8. Avra Synthesis
  9. Axis Clinicals
  10. Bharat Biotech International Ltd
  11. Bijam Biosciences Pvt Ltd
  12. Biochemicals & Synthetic Products Ltd
  13. Biocon
  14. BioGenex Life Sciences Pvt Ltd
  15. Biological E. Ltd
  16. Biological E. Ltd
  17. Biotech Desk Pvt. Ltd
  18. Bramha Scientific
  19. brilliant pharma pvt ltd.
  20. Bulk Drug Manufacturers Association (India)
  21. Cartel Laboratories
  22. Centre for Cellular and Molecular Biology (CCMB)
  23. Cheminor Drugs Ltd
  24. Chemtronik Associates
  25. ChemVeda
  26. Covalent Laboratories Pvt Ltd(Virchow Group)
  27. Divis Laboratories Ltd.
  28. Jagath Reddy’s Heterocyclics
  29. Reddy’s Laboratories
  30. Enal Drugs Pvt. Ltd.
  31. Enon Drugs India Ltd
  32. Erythro Pharma Pvt Ltd
  33. Everest Organics Ltd.
  34. Fleming Laboratories Ltd
  35. Genix Pharma Ltd
  36. Gland Chemicals Pvt. Ltd.
  37. Gland Pharma Ltd
  38. Global Bulk Drugs And Fine Chemicals Ltd.
  39. Glochem Industries Ltd
  40. Granules India Ltd
  41. GVK Bio sciences
  42. hetero Drugs
  43. Indian Genomix Pvt Ltd
  44. Indian Immunologicals
  45. Invitro Biotech Ltd
  46. J & J Dechane Laboratories Pvt. Ltd.
  47. Joflo Industries Pvt Ltd
  48. Jupiter bio sciences
  49. Jvk Biosciences
  50. Kalvik Laboratories Pvt. Ltd.
  51. Kemotheraptik Drugs Ltd
  52. Konar Organics Ltd.
  53. Krebs Biochemicals & Industries Ltd
  54. Laxai Avanthi
  55. Lee Pharma
  56. LifeCare Labs Pvt Ltd
  57. Magene Life Sciences
  58. Makore Labs
  59. MakroCare
  60. Matrix Biosciences Ltd
  61. Medinova Diagnostics Services Ltd.
  62. Meenaxy Pharma Pvt Ltd
  63. Metrochem API Pvt Ltd
  64. MSN Labs
  65. Mylan
  66. Nandan Biomatrix Ltd
  67. Natco Pharma Ltd.
  68. Neozene Bio Sciences Pvt Ltd
  69. Neuland Laboratories Ltd.
  70. Ocimum Biosolutions Ltd
  71. Optimus Pharma Pvt Ltd
  72. Ortin Laboratories Ltd
  73. Otira Pharmaceuticals Pvt Ltd
  74. Oxeeco Technologies Pvt. Ltd.
  75. Pellets pharma
  76. Phaarmasia Ltd
  77. Pharmaceuticals Export Promotion Council
  78. Pharmaceuticals Export Promotion Council
  79. Pharmaids Pharmaceuticals Ltd.
  80. Porus Drugs & Intermediaries Ltd
  81. Prabhat Agri Biotech Ltd
  82. Prk Pharmaceuiticals Pvt. Ltd
  83. Prudential Pharmaceuticals Ltd.
  84. Quiver technologies
  85. Rakshit Drugs Pvt. Ltd.
  86. Ramakrishna Homeo Pharmaceutical Pvt. Ltd.
  87. Rantus Pharma Pvt Ltd
  88. Ravoos Laboratories Ltd
  89. RCC Laboratories India Pvt Ltd
  90. Reddy ‘n’ Reddy Pharmaceuticals
  91. Rnr BioSciences
  92. Rnr Biotech
  93. Saamya Biotech Ltd
  94. Sai Advantium Pharma, Ltd
  95. Sain Medicaments Pvt Ltd
  96. Sainor Laboratories
  97. Shantha Biotechnics
  98. Sapala Organics
  99. saraca Laboratories
  100. Sarvotham Remedies Ltd
  101. SH Pharmaceuticals Ltd
  102. Shodhana Laboratories Limited
  103. Shodhana Laboratories Ltd
  104. Shree Vinayaka Life Sciences Pvt Ltd
  105. Shruti Bulk Drugs Pvt Ltd
  106. Silica Hetero Cyclics
  107. Sipra Labs Pvt. Ltd.
  108. SMS Pharmaceuticals Ltd
  109. Spansules Pharma
  110. Sreepathi Lab Pvt Ltd
  111. Sreepathi Pharmaceuticals Ltd
  112. Sri Annapurna Chemical Industries
  113. Sri Krishna Drugs Ltd.
  114. Sri Krishna Pharmaceuticals Ltd
  115. SRV bio
  116. Sudershan Biotech
  117. Sumac Pharma Pvt Ltd
  118. Suven Life sciences
  119. Symed Laboratories Ltd.
  120. Tejashrri Intermediates Pvt Ltd
  121. Uni Sankyo Ltd
  122. Unicorn Natural Products Pvt. Ltd.
  123. Unique Biotech Ltd
  124. Uni-San Pharmaceuticals
  125. Vance & Health Pharmaceuticals Pvt. Ltd
  126. Vani Chemicals & Intermediates Pvt Ltd
  127. Vasudha Pharma Chem Ltd
  128. Venkat Pharma Ltd
  129. Vetindia Pharmaceuticals Ltd
  130. vimta Labs
  131. Vinar Organics Pvt Ltd
  132. Vins-Bioproducts Limited
  133. Virchow Biotech Pvt Ltd
  134. Virchow laboratories
  135. Virupaksha Laboratories Pvt Ltd
  136. Vishnu Chemicals Pvt Ltd
  137. VIVIN Laboratories Pvt Ltd
  138. Vivo Bio Tech Ltd
  139. Yag Mag Labs Pvt. Ltd.
  140. Yeluri Formulation Pvt Ltd
  141. Yenkey Drugs & Pharmaceuticals Ltd
  142. Zenotech labs Ltd

 

Pharmaceutical Industries in Canada

Entering into the Canadian Pharmaceutical Market has its challenges when it comes to harmonization, regulatory, logistics and export duties. Pharmaceuticals Medicines and Biologics are the priority of any country that produces them, with the highest priority being the manufacture of medications within the country. For this reason, pharmaceutical professionals, pharmacists, chemists and technologists are very important to the pharmaceutical manufacturing industry in Canada. GMD PharmaSolutions provides pharmaceutical manufacturing supply chain solutions to the pharmaceutical and life sciences industries in Canada. The company’s Good Manufacturing Practice facility provides pharmaceutical manufacturers with consistent quality control and supply support across an extensive range of pharmaceuticals products including pharmaceuticals, biologics, bulk APIs and generic drug ingredients.

With the influx of large and small pharmaceutical manufacturing companies into the country, the pharmaceutical industry is experiencing rapid growth. The potential for job creation and development in this sector is very high. With the increase in the number of people moving to Canada and the rest of the world for work and educational opportunities, Canada has become an attractive place to be in, other words it has become a mecca for pharmaceutical engineers. Several international pharmaceutical companies have established plants in Canada, contributing to the country’s pharmaceutical resources and skills.

Many pharmaceutical companies and generic drug producers have entered into joint venture agreements to share the cost and benefit from the research and development of new pharmaceutical drugs and medicines in Canada and the United States. These kinds of ventures are not unheard of but usually require a significant financial outlay, involving both parties. However, when done right and with a good deal of negotiating skill, joint venture opportunities can actually prove to be quite profitable for both parties. So, if you are looking for a career with a solid future and ample opportunities for growth, the pharmaceutical industry may be your perfect choice. Visit the website below for further details on pharmaceutical jobs in Canada and jobs in general in Canada and the United States.

Top 10 Leading Canadian Pharmaceutical Companies

  1. Johnson & Johnson/Actelion
  2. AbbVie
  3. Novartis
  4. Merck/Cubist
  5. Pfizer/Hospira
  6. Apotex
  7. Bayer
  8. Roche
  9. AstraZeneca
  10. GlaxoSmithKline

Major Pharma Companies in Canada

Myovant Sciences Ltd

Gilead Sciences Canada Inc.

Acacia Pharma Ltd

Biohaven Pharmaceuticals

Deciphera Pharmaceuticals, LLC

Genentech USA, Inc.

Immunomedics Inc.

Hoffmann-La Roche Ltd

Eli Lilly and Co.

AstraZeneca

Rhythm Pharmaceuticals, Inc.

Novo Nordisk, Inc.

MorphoSys US, Inc.

Epizyme, Inc.

Horizon Therapeutics

Almirall

Ultragenyx Pharmaceutical Inc.

Trevena Inc.

Recordati Rare Diseases Inc.

Celgene Inc.

Incyte Corp.

Genentech USA, Inc.

Seagen Inc.
Urovant Sciences
NS Pharma, Inc.

Cabotegravir (Vocabria)
ViiV Healthcare ULC
Novartis Pharmaceuticals Corp.
Cedazuridine (Inqovi)C,O
Sun Pharmaceutical Industries Ltd
Laboratoire francais du fractionnement et des biotechnologies S.A.
BioNTech Manufacturing GmbH
Lundbeck Seattle BioPharmaceuticals, Inc.
ViiV Healthcare ULC
Hansa Biopharma AB
Viela Bio, Inc.
Sanofi-Aventis Canada Inc.
Eiger BioPharmaceuticals
Alnylam Pharmaceuticals Inc.
Jazz Pharmaceuticals
Y-mAbs Therapeutics, Inc.

Mumbai Pharma companies – Address Location / Phone Number

  • Macleods pharmaceuticals Ltd Mumbai Andheri (East) 61132900
  • Jenburkt Pharmaceuticals Ltd. Andheri (West) Pharma
  • Pinnacle Bbiomed Wadala (West) 022-40541616
  • Lanz Labs Pvt. Ltd. Andheri (West) 91 22 26205525 / 6750780
  • Laxachem Organics Pvt Ltd Vikhroli (West) 2578 9903
  • Maneesh Pharmaceuticals Ltd. Chembur 91-22-2520 2122 / 23 / 24.
  • Mapra Laboratories Pvt. Ltd. Lower Parel 22 – 2498 3516 / 2498 3517 / 2498 3518
  • Maxheal Pharmaceuticals (india) Jogeshwari (West) 22 42767718
  • Meridian Enterprises Pvt. Ltd. Nariman Point 2266084200, 91-22-22042745
  • Merlin Pharma (p) Limited Malad(West)
  • Piramale life science R tech park 9th flore 30818000
  • RPG life Science Worli / Navi Mumbai “22 2498 1650 / 51
  • 022 6660 6375/ 76 / 77 / 78″
  • Ajanta Pharma Limited Kandivili (West) 22 6606 1000
  • M.J. Biopharm Pvt Limited Taloja. 22020644
  • Emcure Pharmaceuticals Limited Pune
  • Ipca Laboratories Limited
  • GlaxoSmithKline Pharmaceuticals Ltd. Nashik 0253 – 2381273, 0253 – 2382294 0253 – 2382594
  • Lupin Limited HO Bandra (East) 022 6640 2222
  • “Dishman Pharmaceuticals and Chemicals Ltd
  • ” HO -Ahmedabad, Gujarat, Gujarat 079 26443053
  • Intas Pharmaceuticals Ahmedabad, Gujarat, India Gujarat 079 2657 6655
  • Cadila Pharmaceuticals Ltd. Ahmedabad, Gujrat
  • Abbott Healthcare Pvt. Ltd./ india Sion-Trombay Road Chembur 022 67978888
  • Glenamrk Generics Ltd., India Andheri (East) 22 4018 9999
  • Sandoz Private Ltd Airoli 022-27690001 | 27639000 | 27639100 | 61529700
  • Associated Capsules Pvt. Ltd. HO-Nariman Point , Kandivli (West 91-22-3008 9444 / 45
  • SciGen BioPharma Pvt. Ltd. Pune Pune 020 39803220
  • Helvoet Pharma Pune Pune
  • Coral Laboratories Ltd., Nariman Point 22873635 / 22873745
  • Baader Schulz Laboratories Surat
  • Alembic Chemical Works Co. Ltd. Andheri (East) 022 30611698, 022 30611682
  • Aventis (Hoechst Marion Russel)- Now change to SANOFI Andheri (East) 022 2827 8000
  • Bengal Chemicals & Pharmaceuticals Ltd. “S.V. Savarkar Marg
    ” 022 2430 2081 /2437 0428
  • Cipla Limited(M/s. Protac) Mumbai Central 022 2308 2891
  • Hindustan Antibiotics Limited “Pimpri,
    Pune” Pune 020-776511
  • Sequent Scientific Limited 
  • East India Pharma Andheri (East) 26848792 / 32932177
  • Biochem Pharmaceutical Inds 02208 5534
  • “Unichem Laboratories Limited
    ” 022 66 888 333
  • Dishman Pharmaceuticals and Chemicals Ltd “079-26443053,
    – 02717669600 ”
    FDC LIMITED Jogeshwari (West) 022 – 26780652 / 26782653 / 26782656
    (Zandu)Emami Limited Andheri (West) 022 6670 9000
  • BAJAJ HEALTHCARE LTD Mumbai 022-4017 7400/01
  • Bliss GVS pharma LTD “Palghar,
    Dist.Thane” 252525713
  • Chempro Pharma Private Limited “Pushpawati Building, No.1,
    1st Floor, 568 Chirabazar,
  • Girgaon Road, Mumbai – 400002,” 40945239
  • Jyothy Laboratories Limited Andheri (EAST) 66892800
  • Labindia Analytical Instruments Pvt. Ltd. Rabale 22-2598 6244
  • Anchor Health & Beauty Care Pvt. Ltd. Mahesh- 39515555 ,
  • Midas Care Pharmaceuticals Pvt. Ltd. Andheri (East) 22 – 26833409
  • USV Limited Govandi (East) 22-2556-4048
  •  

    KHANDELWAL LABORATORIES PVT. LTD 022 25821793

  • Arch Pharmalabs Ltd.  22-33089200/33089400
    Ideal Cures Pvt. Ltd.
  • Charak Pharma Pvt Ltd 022 2496 5256
  • BHARAT SERUMS & VACCINES LTD. 91-22-61383456

     

  • Unimark Remedies Limited Vile Parle (East) Pharma

     

  • Raptakos Brett & Co. Ltd. 022 4085 6000
  • FRANCO INDIAN PHARMA PVT LTD 022 2493 4026
    BDH Industries LTd 28871370/61551234
    Wockhardt Ltd. 02646 661444
    Flamingo 022-30009300
    “Alkem Laboratories Ltd.
    ” R&D Center , Taloja. C 17/7 , MIDC Industrial Area, Behind Dena Bank, Taloja, Raigad, 022 – 27412274, 27412731, 27412732

     

  • AGLOWMED LIMITED, Mumbai “Aglowmed Limited.
    702 – A, Poonam Chambers,
    Worli, Mumbai – 400 018
    INDIA. ” Worli Pharma 22 40500500
  • Blue Star “Kasturi Buildings,
    Mohan T Advani Chowk,
    Jamshedji Tata Road,
    Mumbai – 400 020
    ” Churchgate Electrical/Electronic Manufacturing 66654000
    Hikal Limited “Taloja
    T-21, M.I.D.C.,
    Taloja,
    Dist. Raigad – 410 208,
    Maharashtra
    ” Pharma 022-3099 0100
  • Enaltec Labs “Kesar Solitaire, 17th Floor,
    Plot No. 5, Sector 19,
    Sanpada, Navi Mumbai,
    Maharashtra – 400 705,” Pharma 91-22-67507000
  • SitecLabs Pvt Ltd Mahape Pharma 22 2778 6200
    PolyPeptide Laboratories Ambarnath ,Thane Pharma 91 2513981916
    Sonu Infrastructures Pvt. Ltd “02512621296
    02512621295”
  • Galaxy Surfactants Ltd C-49/2,TTC Industrial Area, Pawne, Navi Mumbai – 400703 Navi mumbai Production 65134444/27616666
    VVF LTd , Taloja R&D Taloja Chemical Manufacturing 27412036
  • INDEPESCA OVERSEAS PVT.LTD.(TRITON GROUP) Food