Contents of the powerpoint on Pharmacokinetics pharmacodynamics of controlled release systems include:
The term controlled release is associated with therapeutic agents that may be automatically delivered at predetermined rates over long period of time.
The main Goals are :
To reduce the frequency of dosing
To increase the effectiveness of the drug by localizing it
To reduce the dose required
To provide uniform drug delivery
PHARMACOKINETIC MODELS FOR CONTROLLED DRUG DELIVERY
Several models have been proposed to explain the pharmacokinetic behavior of controlled drug delivery systems.
Models of time course profile of absorption and elimination
Loo-Riegelman and Wagner-Nelson model
Model independent pharmacokinetic analysis
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