[PPT] Evaluation of semisolid dosage forms


Contents of the powerpoint on Evaluation of semisolid dosage forms include:
Introduction
Ideal properties of semisolids
Categories of semisolids
Evaluation of ointments
Evaluation of creams
Evaluation of suppositories
conclusion
references

Draize skin irritation test:
A known amount of test substance is introduced under a one square inch gauge patch,
The patch is applied to skin of 12 albino rabbits, (6 with intact skin) and (6 with abraded skin),
The patch is secured in place with adhesive tape and the entire trunk of the animal is wrapped with an impervious material for a 24 hour period,
After 24 hours the patches are removed and resulting reaction is evaluated for erythema and edema formation.
The reaction is again scored at the end of 72 hours and the two readings are averaged.

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