[PPT] Formulation and evaluation of microspheres


Contents of the powerpoint on Formulation and evaluation of microspheres include:
INTRODUCTION
CLASSIFICATION OF POLYMERS.
METHODS OF PREPARATION.
CHARACTERIZATION.
APPLICATIONS.
CONCLUSION.
REFERENCES

POWDERS AND GRANULATES
Free-flowing powders and granulates are needed for a variety of industrial processes. These, however, do not always meet the exacting standards which modern manufacturing demands of them, due to their varying grain size distribution and odd shapes.
These properties are detrimental to efficient processing and lead to agglomeration, inexact dosage, abrading with loss of material, or low reproducibility of castings.
Pharmaceutical applications require highly reproducible dosage and the controlled release of active agents, which can not be achieved with conventional powders and Granulates.

Microparticles or microspheres are defined as small, insoluble, free flowing spherical particles consisting of a polymer matrix and drug. and sized from about 50 nm to about 2 mm.

The term nanospheres is often applied to the smaller spheres (sized 10 to 500 nm) to distinguish them from larger microspheres

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