NAPLEX FPGEE OSPAP KAPS PEBC Pharmacist Exam Quick Revision #1 Pharmacology Guide

NAPLEX FPGEE OSPAP KAPS PEBC Pharmacist Exam Quick Revision #1 Pharmacology Guide

Here Pharmawiki is presenting last day revision for all the aspirants of different pharmacist examinations like  NAPLEX FPGEE OSPAP KAPS PEBC Pharmacist Exam. You can consider it as a Quick Revision on Pharmacology  subject which will help you to qualify and score well in these examinations. This tiny Guide will surely help you to assess your exam preparation level.

NAPLEX FPGEE OSPAP KAPS PEBC Exam Quick Revision

1. venous ulcer treatment >
exclude arteriopathy (eg ABPI), control
oedema, prevent infection, compression bandaging.
2. Cushings – Diagnosis: 24hr urinary free cortisol. Addisons >
short synacthen.
3. Rash on buttocks – Dermatitis herpetiformis (coeliac dx).
4. AF with TIA >
Warfarin. Just TIA’s with no AF >
Aspirin
5. Herpes encephalitis >
temporal lobe calicification OR temporoparietal
attentuation – subacute onset i.e. Several days.
6. Obese woman, papilloedema/headache >
Benign Intercanial
Hypertention.
7. Drug induced pneumonitis >
methotrexate or amiodarone.
8. chest discomfort and dysphagia >
achalasia.
9. foreign travel, macpap rash/flu like illnes >
HIV acute.
10. cause of gout >
dec urinary excretion.
11. bullae on hands and fragule SKIN torn by minor trauma >
porphyria
cutanea tarda.
12. Splenectomy >
need pneumococcal vaccine AT LEAST 2 weeks preop
and for life.
13. primary hrperparathyroidism >
high Ca, normal/low PO4, normal/high
PTH (in elderly).
14. middle aged man with KNEE arthritis >
gonococcal sepsis (older
people >
Staph).
15. sarcoidosis, erythema nodosum, arthropathy >
Loffgrens syndrome
benign, no Rx needed.
16. TREMOR postural,slow progression,titubation, relieved by OH>
benign
essential TREMOR AutDom. (MS – titbation, PD – no titubation)
17. electrolytes disturbance causing confusion – low/high Na.

FPGEE | National Association of Boards of Pharmacy

18. contraindications lung Surgery >
FEV dec bp 130/90, Ace inhibitors (if
proteinuria analgesic induced headache.
21. 1.5 cm difference btwn kidneys >
Renal artery stenosis >
Magnetic
resonance angiogram.
22. temporal tenderness>
temporal arteritis >
steroids > 90% ischaemic
neuropathy, 10% retinal art occlusion.
23. severe retroorbital, daily headache, lacrimation >
cluster headache.
24. pemphigus – involves mouth (mucus membranes), pemphigoid – less
serious NOT mucosa.
25. diagnosis of polyuria >
water deprivation test, then DDAVP.
26. insulinoma >
24 hr supervised fasting hypoglycaemia.
27. Diabetes Random >7 or if >6 OGTT (75g) >
>11.1 also seen in HCT.
28. causes of villous atrophy: coeliac (lymphocytic infiltrate), Whipples , dec
Ig, lymphoma, trop sprue (rx tetracycline).
29. diarrhoea, bronchospasm, flushing, tricuspid stenosis >
gut carcinoid c
liver mets.
3/5/2017 MRCP part 1
https://www.facebook.com/groups/51506029930/permalink/10155082909759931/ 2/5
30. hepatitis B with general deterioration >
hepaocellular carcinoma.
31. albumin normal, total protein high >
myeloma (hypercalcaemia,
electrophoresis).
32. HBSag positive, HB DNA not detectable >
chornic carier.
33. Inf MI, artery invlived >
Right coronary artert.

 

NAPLEX Exam guide

34. Aut dom conditions: Achondroplasia, Ehler Danlos, FAP, FAMILIAL
hyperchol,Gilberts, Huntington’s, Marfans’s, NFT I/II, Most porphyrias,
tuberous sclerosis, vWD, PeutzJeghers.
35. X linked: Beck/Duch musc dyst, alports, Fragile X, G6PD, Haemophilia
A/B.
36. Loud S1: MS, hyperdynamic, short PR. Soft S1: immobile MS, MR.
37. Loud S2: hypertension, AS. Fixed split: ASD. Opening snap: MOBILE
MS, severe near S2.
38. HOCM/MVP inc
by standing, dec by squating (inc all others). HOCM
inc by valsalva, decs all others. Sudden death athlete, FH, Rx.
Amiodarone, ICD.
39. MVP sudden worsening post MI. Harsh systolic murmur radites to
axilla.
40. Dilated Cardiomyopathy: OH, bp, thiamine/selenium deficiency, MD,
cocksackie/HIV, preg, doxorubicin, infiltration (HCT, sarcoid), tachycardia.
41. Restrictive Cardiomyopathy: sclerodermma, amyloid, sarcoid, HCT,
glycogen storage, Gauchers, fibrosis, hypereosinophilia Lofflers,
caracinoid, malignancy, radiotherapy, toxins.
42. Tumor compressing Respiratory tract >
investigation: flow volume
loop.
43. Guillan Barre syndrome: check VITAL CAPACITY.
44. Horners – sweating lost in upper face only – lesion proximal to common
carotid artery.
45. Internuclear opthalmoplegia: medial longitudinal fasciculus connects
CN nucleus 34.
Ipsilateral adduction palsy, contralateral nystagmus. Aide
memoire (TRIES TO YANK THE ipsilateral BAD eye ACROSS THE nose ).
Convergence retraction nystagmus, but convergence reflex is normal.
Causes: MS, SLE, Miller fisher, overdose(barb, phenytoin, TCA), Wernicke.
46. Progressive Supranuclear palsy: Steel Richardson. Absent voluntary
downward gaze, normal dolls eye . i.e. Occulomotor nuclei intact,
supranuclear Pathology .

The Knowledge Assessment of Pharmaceutical Sciences (KAPS) Exam

47. Perinauds syndrome: dorsal midbrain syndrome, damaged midrain and
superior colliculus: impaired upgaze (cf PSNP), lid retraction, convergence
preserved. Causes: pineal tumor, stroke, hydrocephalus, MS.
48. demetia, gait abnormaily, urinary incontinence. Absent papilloedema>
Normal pressure hydrocephalus.
49. acute red eye >
acute closed angle glaucoma >> less common (ant
uveitis, scleritis, episcleritis, subconjuntival haemmorrhage).
50. wheeles, URTICARIA , drug induced >
aspirin.
3/5/2017 MRCP part 1
https://www.facebook.com/groups/51506029930/permalink/10155082909759931/ 3/5
51. sweats and weight gain >
insulinoma.
52. diagnostic test for asthma >
morning dip in PEFR >20%.
53. Causes of SIADH : chest/cerebral/pancreas Pathology , porphyria,
malignancy, Drugs (carbamazepine, chlorpropamide, clofibrate,
atipsychotics, NSAIDs, rifampicin, opiates)
54. Causes of Diabetes Insipidus: Cranial: tumor, infiltration, trauma
Nephrogenic: Lithium, amphoteracin, domeclocycline, prologed
hypercalcaemia/hypornatraemia, FAMILIAL X linked type
55. bisphosphonates:inhibit osteoclast activity, prevent steroid incduced
osteoperosis (vitamin D also).
56.returned from airline flight, TIA>
paradoxical embolus do TOE.
57. alcoholic, given glucose develops nystagmus >
B1 deficiency
(wernickes). Confabulation>
korsakoff.
58. monoartropathy
with thiazide >
gout (neg birefringence). NO
ALLOPURINOL for acute.
59. painful 3rd nerve palsy >
posterior communicating artery aneurysm till
proven otherwise
60 late complication of scleroderma >
pumonaryhypertention plus/minus
fibrosis.
61. causes of erythema mutliforme: lamotrigine
62. vomiting, abdominal pain, hypothyroidism >
Addisonian crisis (TFT
typically abnormal in this setting DO NOT give thyroxine).
63. mouth/genital ulcers and oligarthritis >
behcets (also eye /SKIN
lesions, DVT)
64. mixed drug overdose most important step >
Nacetylcysteine (time
dependent prognosis)
65. cavernous sinus syndrome 3rd
nerve palsy, proptosis, periorbital
swlling, conj injectn
66. asymetric parkinsons >
likely to be idiopathic
67. Obese, NIDDM female with abnormal LFT’s >
NASH (nonalcoholic
steatotic hepatitis)
68. fluctuating level of conciousness in elderly plus/minus deterioration >
chronic subdural. Can last even longer than 6 months
69. Sensitivity >
TP/(TP plus FN) e.g. For SLE ANA
highly sens,
dsDNA:highly specific
70. RR is 8%. NNT is >
100/8 >
50/4 >
25/2 >
13.5

Australian Pharmacy Council

71. ipsilateral ataxia, Horners, contralateral loss pain/temp >
PICA stroke
(lateral medulary syndrome of Wallenburg)
72. renal stones (80% calcium, 10% uric acid, 5% ammonium (proteus),
3% other). Uric acid and cyteine stone are radioluscent.
73. hyperprolactinaemia (allactorrohea, amenorrohea, low FSH/LH) >
Da
antags (metoclopramide, chlorpromazine, cimetidine NOT TCA’s),
pregnancy, PCOS, pit tumor/microadenoma, stress.
74. Distal, asymetric arthropathy >
PSORIASIS
3/5/2017 MRCP part 1
https://www.facebook.com/groups/51506029930/permalink/10155082909759931/ 4/5
75. episodic headache with tachycardia >
phaeochromocytoma
76. very raised WCC >
ALWAYS think of leukaemia.

OSPAP qualification

77. Diagnosis of CLL >
immunophenotyping NOT cytogenetics, NOT
bone marrow
78. Prognostic factors for AML >
bm karyotype (good/poor/standard) >>
WCC at diagnosis.
79. pancytopenia with raised MCV >
check B12/folate first (other causes
possble, but do this FIRST). Often associayed with phenytoin use >
decreased folate
80. miscariage, DVT, stroke >
LUPUS anticoagulant >
lifelong
anticoagulation
81. Hb elevated, dec ESR >
polycythaemua (2ndry if paO2 low)
82. anosmia, delayed puberty >
Kallmans syndrome (hypogonadotrophic
hypogonadism)
83. diag of PKD >
renal US even if think anorexia nervosa
85. commonest finding in G6PD hamolysis >
haumoglobinuria
86. mitral stenosis: loud S1 (soft s1 if severe), opening snap.. Immobile
valve >
no snap.

PEBC Guide to Pharmacist

87. Flank pain, urinalysis:blood, protein >
renal vein thrombosis. Causes:
nephrotic syndrome, RCC, amyloid, acute pyelonephritis, SLE
(atiphospholipid syndrome which is recurrent thrombosis, fetal loss, dec plt.
Usual cause of cns manifestations assoc with LUPUS ancoagulant,
anticardiolipin ab)
88. anaemia in the elderly assume GI malignancy
89. hypothermia, acute renal failure >
rhabdomyolysis (collapse assumed)
90. pain, numbness lateral upper thigh >
meralgia paraesthesia (lat
cutaneous nerve compression usally by by ing ligament)
91. diagnosis of haemochromatosis: screen with Ferritin, confirm by
tranferrin saturation, genotyping. If nondiagnostic do liver biopsy 0.3%
mortality
92. 40 mg hidrocortisone divided doses (bd) >
10 mg prednisolone (ie.
Prednislone is x4 stronger)
93. BTS: TB guidlines – close contacts >
Heaf test >
positive CXR,
negative >
repeat Heaf in 6 weeks. Isolation not required.
94. Diptheria >
exudative pharyngitis, lymphadenopathy, cardio and neuro
toxicity.
95. Indurated plaques on cheeks, scarring alopecia, hyperkeratosis over
hair follicles >>
Discoid LUPUS
96. wt loss, malabsoption, inc ALP >
pancreatic cancer
97. foreign travel, tender RUQ, raised ALP >
liver abscess do U/S
98. wt loss, anaemia (macro/micro), no obvious cause >
coeliac (diarrhoea
does NOT have to be present)
99. haematuria, proteinuria, best investigation >
if glomerulonephritis
suspected >
renal biopsy

100. Acromegaly – Diagnosis: OGTT followed by GH conc.
101. Malaria, incubation within 3/12. can be relapsing /remitting. Vivax and
Ovale (West Africa) longer imcubation.
102. Fever, lymphadenopathy, lymphocytosis, pharygitis >
EBV >
heterophile antibodies
103. GI bleed after endovascular AAA Surgery >
aortoenteric fistula