[PPT] Evaluation of Oral Controlled drug delivery systems


Contents of the powerpoint on Evaluation of Oral Controlled drug delivery systems include:
INTRODUCTION
ADVANTAGES AND DISADVANTAGES
ATTRIBUTES OF DRUG CANDIDATE FOR CONTROLLED RELEASE SYSTEMS
INVITRO-INVIVO EVALUATION OF
FLOATING DRUG DELIVERY SYSTEM
BIOADHESIVE DRUG DELIVERY SYSTEM
BUCCAL BIOADHESIVE DRUG DELIVERY SYSTEM
COLON SPECIFIC DRUG DELIVERY SYSTEM
CONCLUSION
REFERENCES

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[PPT] Evaluation of Colloidal Drug Delivery Systems


Contents of the powerpoint on Evaluation of Colloidal Drug Delivery Systems include:
Introduction

Classification colloidal drug delivery systems

Evaluation techniques of,

Liposomes

Niosomes

Nanoparticles

Microemulsions

Conclusion

References.

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[PPT] Liposome – Formation, Preparation, Properties and Applications


Contents of the powerpoint on Liposome – Formation, Preparation, Properties and Applications include:
Definition of Liposomes
Salient features
Classification of Liposomes

SUV = Small Unilamellar Vesicles
LUV = Large Unilamellar Vesicles
MLV = Multilamellar Vesicles
LLC = Lamellar Liquid Crystalline Phase
MVV = Multivesicular vesicles

Liposomes are composed of one to several
hundreds concentric membranes

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[PPT] Types of Coating Pans


Contents of the powerpoint on Types of Coating Pans include:
1) Coating Process
2) TYPES OF COATING PANS
CONVENTIONAL COATING PANS
PERFORATED COATING PANS
3)VALIDATION OF COATING PANS
IQ
OQ
PQ
4)REFERENCES

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[PPT] Self Emulsifying Drug Delivery Systems (SEDDS)


Contents of the powerpoint on Self Emulsifying Drug Delivery Systems (SEDDS) include:
INTRODUCTION
DEFINITION AND ADVANTAGES
FORMULATION OF SEDDS
PREPARATION OF SEDDS
MECHANISM OF SELF EMULSIFICATION
IN VITRO EVALUATION OF SEDDS
IMPROVEMENT OF ORAL ABSORPTION BY SEDDS
APPLICATIONS OF SEDDS
SOLID SEDDS
RECENT APPROACHES IN SEDDS
CONCLUSION
REFERENCES

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[PPT] Resealed Erythrocytes


Contents of the powerpoint on Resealed Erythrocytes include:
Introduction
Basic concept of RBC
Drug carrying potential of RBC
Advantages and Limitations
Source and isolation of RBC
Methods of drug loading
In vitro characterization
Shelf and storage stability
Mechanisms of drug release
Applications
References

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[PPT] Prodrugs


Contents of the powerpoint on Prodrugs include:
Introduction
Various approaches to enhance efficacy of the drug
Hard and soft drugs
Prodrugs
Classification of prodrugs
Considerations in the design of prodrugs
Strategies in the design of prodrugs
Applications of prodrugs
Prodrug based novel drug delivery approaches
Conclusion
References

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[PPT] Ocusert- Drug delivery method


Contents of the powerpoint on Ocusert- Drug delivery method include:
Introduction
Anatomy of eye
Routes of ocular delivery
Absorption of drugs in eye
Pre-corneal disposition
Trans-corneal penetration
Conventional ocular drug delivery systems
Criteria for selection of ocular dosage form
Ocular controlled drug delivery devices
Requirements for success
Advantages and disadvantages
Classification
Preparation of ocular insert
Characterization of inserts
Packaging
How to use
Conclusion
References

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[PPT] Niosomes – Drug delivery systems


Contents of the powerpoint on Niosomes – Drug delivery systems include:
Introduction
Structure of niosomes
Materials used in the preparation of niosomes
Advantages & disadvantages of niosomes
Formation of niosomes from proniosomes
Methods of preparation
Size reduction methods & drug loading
Encapsulation of drugs & removal of unentrapped drug
Characterization of niosomes
Stability of niosomes
Applications
Recent advances in niosomes
Conclusion
References

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[PPT] Multiple Emulsions – Types, Preparation and Applications”


Contents of the powerpoint on Multiple Emulsions include:
INTRODUCTION
TYPES OF MULTIPLE EMULSIONS
PREPARATION OF MULTIPLE EMULSIONS
IN VITRO CHARACTERIZATION
STABILITY OF MULTIPLE EMULSIONS
APPLICATIONS
CONCLUSION
REFERENCES

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“Unlocking the Potential of Multiple Emulsions: Types, Preparation, Characterization, Stability, and Applications”

Introduction to Multiple Emulsions

Multiple emulsions, a fascinating class of colloidal systems, offer unique advantages in various industries, from pharmaceuticals to cosmetics and food technology. These complex emulsions, often referred to as “W/O/W” (water-in-oil-in-water), are engineered structures comprising multiple layers of aqueous and oil phases. In this comprehensive exploration, we delve into the world of multiple emulsions, covering their types, preparation methods, in vitro characterization, stability considerations, and versatile applications.

Types of Multiple Emulsions

Multiple emulsions come in several types, each tailored to specific applications and encapsulation requirements. The primary types include:

W/O/W Multiple Emulsions: In this classic configuration, water droplets are dispersed within oil, which is subsequently enveloped by an outer water phase. This type is ideal for encapsulating hydrophilic compounds while protecting them from the external environment.

O/W/O Multiple Emulsions: In the reverse scenario, oil droplets are surrounded by water, forming a water-in-oil-in-water emulsion. This type is suitable for entrapping lipophilic substances within an aqueous medium.

S/O/W and S/W/O Multiple Emulsions: These specialty emulsions incorporate a solid phase (S) in addition to the aqueous and oil phases, expanding their applications in controlled release and encapsulation.

Preparation of Multiple Emulsions

Multiple emulsions can be prepared using various techniques, offering control over their composition and structure:

Two-Step Emulsification: This method involves creating a primary emulsion, typically a water-in-oil (W/O) emulsion, followed by the addition of an outer aqueous phase to form the final water-in-oil-in-water (W/O/W) multiple emulsion.

Phase Inversion Methods: These techniques induce phase inversion between W/O and O/W emulsions by altering factors like temperature or the addition of co-surfactants. This approach provides versatility in emulsion design.

In Vitro Characterization of Multiple Emulsions

Characterization is crucial for understanding the properties and behavior of multiple emulsions. In vitro characterization methods include:

Microscopy: Optical and electron microscopy enable visualizing the internal structure, including droplet size and distribution.

Particle Size Analysis: Techniques like dynamic light scattering (DLS) assess droplet size distribution, influencing stability and performance.

Rheology: Measuring viscosity and flow behavior helps determine the emulsion’s physical properties.

Zeta Potential: Assessing surface charge aids in predicting stability, as droplets with varying charges may repel or attract each other.

Stability of Multiple Emulsions

Stability is a critical aspect of multiple emulsions due to their intricate structure. Factors affecting stability include:

Ostwald Ripening: The growth of larger droplets at the expense of smaller ones over time, potentially causing instability.

Flocculation and Creaming: Aggregation and vertical migration of droplets can lead to phase separation.

Coalescence: The merging of adjacent droplets may result in the formation of larger droplets and eventual phase separation.

Applications of Multiple Emulsions

Multiple emulsions find diverse applications across industries, including:

Pharmaceuticals: Controlled drug delivery systems, enhancing drug solubility, and targeted therapies.

Cosmetics: Encapsulation of active ingredients, improving skin care and cosmetics products.

Food Technology: Enhanced flavor and aroma delivery, controlled release of nutrients, and improved food product quality.

Biotechnology: Encapsulation of enzymes and biologically active compounds for various applications.

Agriculture: Controlled release of fertilizers and pesticides for improved crop yield and sustainability.

Environmental Remediation: Delivery of remediation agents for cleaning up contaminated sites.

In summary, multiple emulsions are versatile systems with a wide range of applications, underpinned by their unique structure and properties. Understanding their types, preparation methods, characterization techniques, stability considerations, and diverse applications is crucial for harnessing their potential across industries.