After B Pharm???? What to do After B Pharmacy????

After B Pharm What to do after b pharmacy

After B Pharm???? What to do after completing B Pharmacy? Is this your question? Are you in dilemma?  Don’t worry we show you what all opportunities you have once you get B Pharm Consolidate. There are many Government and Private jobs for you. You can choose any of your choice and work hard to achieve it.

After B Pharm What to do after b pharmacy
After B Pharm What to do after b pharmacy

What to do After B Pharmacy????

Drug Inspector
Government Pharmacist
RRB Pharmacist
State government Pharmacist
Private Pharmacist
Pharmaceutical Marketing
Manufacturing Companies
Regulatory Affairs
Medical Underwriting
Pharmaceutial Production
Medical Transcription
Quality Control
Quality Analists
clinical trials
data analysis,
pharmacovigilance
Regulatory affairs

Other Government Jobs?

State government Jobs like Group 1 Group 2 Group 4 Services
SSC Staff seclection Commission
UPSC
Civils
State PSC
Bank jobs

HIGHER EDUCATION

Courses:

Training in clinical trials, patents, data analysis, pharmacovigilance Regulatory affairs.

M. PHARM:

M. Pharm can be done in pharmaceutics, pharmacology, pharmaceutical chemistry, clinical pharmacology, pharmacognosy, biotechnology, etc After M.Pharm pharmacists gets higher pays in production and quality control etc. You also get additional opportunities like as lecturer, in research, as medical data analyst and in promising field of pharmacovigilance.

MBA:

After B.Pharm graduates an pursue MBA from reputed institute to get management Jobs in Heath Care and Pharmaceutical Industry. Some universities offer pharma management courses also. If MBA Institute is reputed you will get good package.

.

MS:

Those who are interested in doing job in pharmaceutical companies in foreign countries can pursue Master of Science in pharmacy and related MS degrees from foreign universities. NIPER in India also provide MS Pharm Course. In India scope OF MS Pharm is similar to M. Pharm

PHD:

PHD is suitable to those who are interested in research, and professors jobs in government colleges. After PHD salaries are handsome in reputed companies and government colleges. Though After recession Job opportunities for PHD freshers are reduced like other professions.

LLB:

You can even pursue LLB to become lawyer and specialize in pharmaceutical jurisprudence, intellectual property law, patents, etc.

GPAT Preparation Books Subject-wise – GPAT MATERIAL PDF – Pharmacy Previous Papers

GPAT Preparation Books Subject-wise - GPAT MATERIAL PDF - Pharmacy Previous Papers

GPAT Preparation Books Subject-wise: The Graduate Pharmacy Aptitude Test is called as GPAT, which is an annual all India examination conducted by All India Council for Technical Education, New Delhi. The test is for the evaluation of Pharmacy graduates candidates seeking admission into the Masters (M. Pharm) program in recognized universities and private colleges offering Post Graduation studies in Pharmacy. The results are also used to determine eligibility of students for scholarships and other financial assistance.

GPAT Preparation Books Subject-wise - GPAT MATERIAL PDF - Pharmacy Previous Papers
GPAT Preparation Books Subject-wise – GPAT MATERIAL PDF – Pharmacy Previous Papers

It consists of Multiple Choice Questions from the subjects such as Pharmaceutics, Pharmaceutical Analysis, Pharmacognosy, Medicinal Chemistry, Biochemistry, Organic Chemistry, Pharmacology, Microbiology and Basics of Pharmaceutical Sciences. There will be emphasis on analytical chemistry as well with questions mostly from B. Pharmacy syllabus. Numerical part is also very important part of the exam and most students are prone to skip them. Generally, the numerical questions that are asked in the exam are from Pharmacokinetics, Posology. Hence it is recommended to solve numerical sums right from the B.Pharm course when one aims for GPAT. GPAT Exam is considered to be one of the most important exams so it is must for the student to do the best preparation. Students those appearing for GPAT have to study standard textbooks for good score in GPAT. For thorough study, one needs to study in details the subjects allotted. Following the syllabus of the GPAT is essential as the exam is held every year in the month of January tentatively.

The list of the study materials and books are as follows:

GPAT Books for Basics of Pharmaceutical Sciences

  • Health Education & Community Pharmacy: For First Year Diploma by N. S. Parmar
  • Remington : The Science and Practice of Pharmacy : Alfonso R Gennaro
  • The Theory And Practice Of Industrial Pharmacy : Lachman

GPAT Books for Organic Chemistry: 

  • By Morrison & Boyd
  • Advance Organic Chemistry: Reaction, Mechanism & Structure by Jerry March

GPAT Books for Medicinal Chemistry: 

  • By Wilson & Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry 11th Ed.

GPAT Books for Biochemistry:

  • Biochemistry: By Lehninger
  • By Satyanarayan

EBooks:

  • Biochemistry of Lipids, Lipoproteins and Membranes edited by J.E. Vance, Dennis E. Vance
  • Biochemistry and Clinical Pathology by By M. R. Chaudhari, Y. A. Kulkarni, S. B. Gokhale
  • Lipids: Biochemistry, Biotechnology and Health By Michael I. Gurr, John L. Harwood, Keith N

GPAT Books for Physical Chemistry:

EBooks:

  • Physical Chemistry by Dr. R. R. Misra
  • Physical Chemistry Lecture Notes by Prof. Rob Schurko R.W. Schurko, University of Windsor
  • Introductory Physical Chemistry bynbsp; Rob Schurko
  • Advanced Physical Chemistry By Carol A. Venanzi

GPAT Books for Pharmacology: 

  • Rang & Dale, K.D. Tripati, Goodman & Gilman.

EBooks:

  • Pharmacology Test Prep: 1500 USMLE-Style Questions & Answers, By Mario Babbini, Mary L. Thomas
  • Basic and Clinical Pharmacology 14E by Bertram G. Katzung, Anthony J. Trevor

GPAT Books for Pharmaceutics:

  • Pharmaceutics: The Science of Dosage Form Design by Aulton
  • Physical Pharmacy by Martin.
  • By Ansel

EBooks:

  • Modern Pharmaceutics by banker Rhodes

 

GPAT Books for Pharmaceutical Analysis:

  • Spectroscopy – Silverstein
  • Instrumental methods of Chemical Analysis – B. K. Sarma
  • Text Book of Pharmaceutical Analysis – K. A. Connors
  • Instrumental methods of Chemical Analysis – Chatwal
  • Analytical Chemistry Skoog’s
  • By Dr. Ravi Shankar

GPAT Books for Microbiology:

  • Industrial microbiology by Cascida
  • Microbiology by Pelzar
  • Industrial microbiology by Prescott and Dunn

GPAT Books for Pharmacognosy:

  • Text Book of Pharmacognosy by K. Kokate
  • Text Book of Pharmacognosy by E. Walis
  • Text Book of Pharmacognosy by Treas and Evans

GPAT Books are according to the subjects, so you might have some difficulty to get the books for GPAT according to the subjects. If one wants to get admission in these courses then he/she must refer to the best GPAT preparation books and GPAT Subject-Wise Study Material. One may refer to the also refer the GPAT entrance examination books that will help as a guide and the eBooks in PDF can be downloaded too. Here we have tried our best to compile the books subject wise so that the readers don’t have to put much effort and time in the searching process. Hope this information will definitely help the candidates to do the best preparation for the exam.

All the best!

GPAT Sample Questions:

21-One fluid ounce is?
Ans-30 ml
Note- A fluid ounce (abbreviated fl oz) is a unit of volume (also called capacity) typically used for measuring liquids.

22-The plant drug which is oxytocic?
Ans-Ergot
Note- Oxytocic are the agents that stimulate uterine contraction, used in Induction of labor and to control postpartum bleeding. Ergot Alkaloids- Ergometrine & Methyl ergometrine is used.

23-The diagnostic agent used for the functioning of thyroid gland?
Ans-I-131
Note- Thyroid gland produce, store, and release hormones into the bloodstream so the hormones can reach the body’s cells. The thyroid gland uses iodine from the foods you eat to make two main hormones: Triiodothyronine (T3) and Thyroxine (T4)

24-The constituent of cholesterol termed as bad cholesterol is?
Ans-LDL
Note- VLDL cholesterol is a type of blood fat. It’s considered one of the “bad” forms of cholesterol, along with LDL cholesterol and triglycerides. (LDL) are called as “bad” cholesterol. High levels of LDL cholesterol can build up in your arteries, causing heart disease.

25-Sterols belongs to the class of?
Ans-Lipids
Note- Sterols, also known as steroid alcohols, are a subgroup of the steroids, occur naturally in plants, animals, and fungi, with the most familiar type of animal sterol being cholesterol.

26-Hepatitis is a?
Ans-Viral infection
Note- Hepatitis is inflammation of the liver tissue, There are five main types of viral hepatitis: Type A, B, C, D, and E.

27-A leukotriene receptor antagonist used in allergic cough is?
Ans-Montelukast
Note- Leukotriene receptor antagonists, such as montelukast, zafirlukast, and pranlukast used to treat allergies and prevent asthma attacks.

28-The sulphonamide used in burn therapy is?
Ans-Sulfadiazine
Note- Sulphonamides are synthetic antimicrobial agents that contain the sulfonamide group.silver sulfadiazine is applied to the skin to treat and prevent wound infections associated with second or third degree burns.

29-A hypotonic solution made isotonic by adding?
Ans-Sodium chloride
Note- Hypertonic solution is a particular type of solution that has a greater concentration of solutes on the outside of a cell when compared with the inside of a cell.
Hypertonic solution is a particular type of solution that has a greater concentration of solutes on the inside of a cell when compared with the outside of a cell.

30-The pathogenic organism in milk is killed by?
Ans-Pasteurization
Note- Pasteurization to kill pathogenic bacteria has helped reduce the transmission of diseases, such as typhoid fever, tuberculosis, polio etc.

GPAT Books are according to the subjects, so you might have some difficulty to get the books for GPAT according to the subjects. If one wants to get admission in these courses then he/she must refer to the best GPAT preparation books and GPAT Subject-Wise Study Material. One may refer to the also refer the GPAT entrance examination books that will help as a guide and the eBooks in PDF can be downloaded too. Here we have tried our best to compile the books subject wise so that the readers don’t have to put much effort and time in the searching process. Hope this information will definitely help the candidates to do the best preparation for the exam.

All the best for your GPAT Examination!

Drug Inspector Exam- DI Subjects Syllabus Books & Practice Model Papers 2018 2019

Drug Inspector Exam- DI Subjects Syllabus Books & Practice Model Papers 2018 2019

Drug Inspector exam- Subjects, Syllabus, Books, and Practice Papers are  here in this article. The Government exam of Drug Inspector is conducted by the Union Public Service Commission known as UPSC and also various state PSCs and Staff Selection committees on an annual basis. All the interested candidates those are eligible can register application form after going through the UPSC Drug Inspector Notification released every year. According to the official notification, the application is invited to online mode and candidates can register from December month of the year. The vacancies are available for the appointment of Drug Inspector vacancy in various departments. Additional details about eligibility criteria like qualification, a method of the application procedure, selection process and other required details are also available on the official website. The recruitment process for these Drug Inspector vacancies will be completed by the next year in the month of October. All the qualified candidates who are aspiring to be the Drug Inspector, they can send the application form to exam community with the help of postal services. The application fee can be paid offline or online mode before the deadline.

Aspirants who are seeking for Drug inspector posts should possess the bachelor degree in medicine/ science/degree in Pharmacy with minimum 45% marks in the qualifying exam from any PCI recognized university. All the job seekers who want to work as Drug inspector should have a minimum experience of 18 months in the testing/manufacturing field or be a registered Pharmacist. Candidate should be Indian citizen; minimum age should be 35 years and maximum 50 years as per the government rules & regulation. Relaxation of 5 years is allowed for the reserved category. A category wise or state wise recruitment details are available in the official advertisement.

For the candidate to be aware of the curriculum here we are notifying the subjects, syllabus, books and the practice papers of the Drug Inspector Exam.

 

Drug Inspector Exam- DI – Exam Pattern

Paper Subject Marks Duration
Paper-I Pharmacy 200 marks 2 Hours
Paper-II General  Studies and Mental Ability 50 marks 1 Hour

Check here Drug Inspector Exam Solved papers

Drug Inspector Exam- DI Pharmacy Syllabus

 

Human Anatomy & Physiology Pharmacognosy
Clinical Pathology Biochemistry
Drug Store Management Pharmaceutical Chemistry
Pharmaceutics Hospital & Clinical Pharmacy
Pharmacology Pharmaceutical Jurisprudence
Accountancy Health Education & Community Pharmacy
Toxicology Commerce

 

 

Drug Inspector Exam- DI General Studies and Mental Ability Syllabus

 

Drug Inspector Exam- DI General Knowledge

 

Indian Constitution Science – Inventions & Discoveries
History Budget and Five Year Plans
Geography Important Financial & Economic News
Economy Scientific Research
Culture India and its neighbouring countries
Sports Knowledge of Current Events
General Politics Current Affairs – National & International
Economy, Banking, and Finance Countries & Capitals

 

Drug Inspector Exam- DI General Intelligence

 
Logical Reasoning Syllogism
Blood Relations Input Output
Coding Decoding Alphanumeric Series
Ranking/Direction/Alphabet Test Data Sufficiency
Coded Inequalities Seating Arrangement
Puzzle Tabulation  

 

Drug Inspector Exam- DI English

 

Articles Prepositions
Tenses Verbs
Synonyms Antonyms
Proverbs Conjunctions
Sentences Structure Phrases
Unseen Passage Vocabulary

Drug Inspector Exam- DI Tentative books recommended

  • Tutorial Pharmacy by Cooper and Gunn
  • Forensic Pharmacy by C. Kokate (for the drug laws)
  • General Studies Paper I for Civil Services Preliminary Examination 2018
  • Lucents General Knowledge book
  • NCERT Books Set (English Medium) for UPSC Exam (Prelims, Mains), IAS, Civil Services, IFS, IES and other exams

 Check more about Drug Inspector Exam

Drug Inspector Exam- DI Model Test Papers

  • Pharmarocks- The Way of Success DI study material booklet, model papers by Mr. Amar Raval
  • One can follow our website for the latest updates of the mock papers for self-practice.

Drug Inspector Exam- DI Subjects Syllabus Books & Practice Model Papers 2018 2019

It depends on the state level as well as the central level based on which the general studies including the G.K questions may come. All those candidates who are going to attempt the examination must prepare through the previous year papers, Drug inspector model papers. If anyone is admitted to coaching classes then most of the centres will also make the student practice previous year question paper. The old question papers can be downloaded for free from the internet.

Drug Inspector Exam Practice:

Here are few basics You must know.

  • A break in a capsule is a fracture in the surface of the capsule.
  • A break in a tablet is the separation or dislodging of more than
    10 percent of the tablet.
  • Caking in suspensions is the settling of the solid material in a suspension tothe bottom; the cake does not easily redisperse on shaking.
  • Capping or cavitations of tablets is the separation (or tendency toward separation) of aportion of the upper or lower surface of the tablet.
  • Capsule shapes bulletlike
    conventional
    elliptical (oval)
    oblong
    round
    tapered ends
    various special shapes
  • Capsule types • hard gelatin shell that consists of two pieces:
  • a base containing the medicine and a cap covering
    the base 
  • soft gelatin shell consisting of two flexible pieces formed into a body that is permanently sealed and that may contain a liquid, powder, or semisolid.
  • Chain of custody is the record of individuals who have accessed sample material from the time of collection by an inspector until its ultimate destruction. Both the record and the sample, from its time of collection to the time of its destruction, must be kept safely (under key and lock) and under systematic control.
  • Certificate of Analysis is a document supplied by the manufacturer summarising the physical and analytical data for a particular lot or batch of drug product; is the basis for the product batch or lot being released for sale.
  • Chipping is removal of parts of the tablet, usually at the edges; caused by low friability.
  • Confiscate is to officially take away from a vendor or importer
    and to assume custody of a drug consignment stocked
    on the premises or at the port of entry. The intention
    is to stop the drugs’ distribution to the public. Usually
    done for drugs shown to be counterfeit or of
    substandard quality or associated with unexpected
    illness or death.
    Consignment or “R” number is a consignment tracking reference number assigned
    by the India Revenue Authority. “R” stands for
    “reference.” This number, together with the date,
    distinctively identifies an imported consignment.
  • Detain is to perform the following actions:
    1. Write “DETAIN” in the space provided in the Port of Entry Consignment Inspection Form.
    2. Stop the inspection, complete the Rejection/Detention Form, and inform the India  Revenue Authority/Customs and Excise Department of the rejection or detention.
    3. Give a copy of the form to the India Revenue Authority and the customer.
    4. Refer the importer/consignee to the TFDA.
    5. Upon resolution of detention issues by written instructions from the TFDA, continue the inspection
    from where it stopped.
  • Detention is the retention of a consignment pending resolution of outstanding issues by the TFDA. However, if the issues are not resolved to the satisfaction of the TFDA, detention status, upon written instructions
    from the TFDA, is converted to rejection.
  • Final Classification and Valuation Report is prepared at the exporting country port by COTECNA, which is the third-party contractor to the India Revenue Authority/Customs and Excise Department. The Final  Classification and Valuation
    Report, a Customs and Excise Department document, confirms that the imported goods have the correct
    quality, quantity, and value.
    First expiring, first out is a practice intended to keep the product inventory in good rotation to prevent pharmaceuticals and supplies from expiring on the shelf.
    GPHF Minilab stands for German Pharma Health Fund Minilab, a pharmaceutical product testing kit that has materials for colour reaction, thin-layer chromatography, and disintegration testing of essential drugs.
  • Immediate container is a type of packaging such as a tin or a bottle that is in direct contact with the medicine; also referred to as the “primary container.”
  • Import Certificate is a document issued by the TFDA authorising the importation of approved drugs into the country.
    Liquid or semisolid dosage forms can be a clear liquid, a suspension, or a dry powder for a suspension that must be reconstituted as directed on the manufacturer’s label before use.
  • Percent (%) of remaining shelf life This value is equal to:
    (Expiry date – Date on receipt at port of entry) × 100
    (Expiry date – Manufacturing date)
    Or:
    (Remaining shelf life on arrival) × 100
    (Shelf life of the product)
  • Port of entry name is the name of an authorised place of entry for drug consignments; this name must be filled in on the Port of Entry Consignment Inspection Form.
  • Pro Forma Invoice is presented to the TFDA for approval before a shipment can enter India . A properly endorsed Pro Forma Invoice has two signatures from TFDA officials and the TFDA stamp. The signatures and the stamp indicate that the exporter and consignee are both properly licensed and that the drug manufacturer, product, and dosage forms are in compliance with TFDA requirements. 
  • Quarantine is the retention of a consignment, not allowing its use until further tests are performed to ascertain its quality.
  • Sample Receipt Form is a document drug inspectors must complete for every sample of a batch of drug product collected.
  • Secondary container is a type of packaging that holds a number of immediate or primary containers.
    Splitting of a tablet describes the partial or complete separation of the top or bottom crowns of a tablet from the main body.
  • Surveillance Programme Document defines which pharmaceutical products are to be
    examined, collected, and tested.
  • Tablet types buccal
    hypodermic
    impregnated (including delayed-action, repeat-action,
    prolonged-action, and sustained-action tablets)
    ophthalmic
    oral
    pellet
    solution
    sublingual
    vaginal

B. Pharmacy 3rd Year Subjects & Syllabus – PDF B Pharm Second Year 5 + 6 Semester

B. Pharmacy 3rd Year Subjects & Syllabus - PDF B Pharm Second Year 5 + 6 Semester

B. Pharmacy 3rd Year Subjects and Syllabus

According to reports every year millions of students are joining B. Pharmacy to study Pharmacy as this is one of the finest education degrees. In the 3rd year of B. Pharm degree, every candidate shall be required to work for at least 150 hours spread over four weeks in a Pharmaceutical Industry/Hospital. It includes Production unit, Quality Control department, Quality Assurance department, Analytical laboratory, Chemical manufacturing unit, Pharmaceutical R&D, Hospital (Clinical Pharmacy), Clinical Research Organization, Community Pharmacy, etc. In between the Semester 6 and Semester 7 one shall submit a satisfactory report of such work and certificate duly signed by the authority of training organization to the head of the institute. Hence, let us also get acquainted with some terms related to the Pharmacy profession.

In the Pharmaceutical Industry, pharmacists are employed in manufacturing, product development, research, quality control, quality assurance, marketing, sales and administration. Community/Retail Pharmacy encompasses the practice of pharmacy in community settings or retail outlets. Pharmacists, (themselves become the owner of their own pharmacies) are actively educate patients, maintain and monitor drug records and ensure information resource of the highest calibre. Regulatory Bodies control and regulate medicines for the Drug and Pharmaceutical industry. At the federal or provincial level, posts like drug inspectors, drug controllers, and pharmacist/chief pharmacists at drug testing laboratories and Commissioned officers in Armed Forces are deployed.

The curriculum of the B. Pharm 3rd year is as follows:

B pharm Subjects for 3rd year (Semester 5)

Subjects Theory Practical
Hours Marks Hours Marks
MEDICINAL CHEMISTRY-II 45 100    
INDUSTRIAL PHARMACY 45 100 4/week 50
PHARMACOLOGY-II 45 100 4/week 50
PHARMACOGNOSY AND PHYTOCHEMISTRY II 45 100 4/week 50
PHARMACEUTICAL JURISPRUDENCE 45 100    
   
Total marks 650

 

 

 

 

B pharmacy Syllabus for Semester 5

Subject: MEDICINAL CHEMISTRY – II

Theory
Unit I

Antihistaminic agents: Histamine, receptors and their distribution in the Human body

H1–antagonists: Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamines cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride*, Phenidamine tartarate, Promethazine hydrochloride*, Trimeprazine tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine Cromolyn sodium

H2-antagonists: Cimetidine*, Famotidine, Ranitidin.

Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole

Anti-neoplastic agents:

Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa

Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate*, Azathioprine

Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin

Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate

Miscellaneous: Cisplatin, Mitotane

Unit II

Anti-anginal:

Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate, Isosorbide dinitrite*, Dipyridamole.

Calcium channel blockers: Verapamil, Bepridil hydrochloride, Diltiazem hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.

Diuretics: Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide. Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide,

Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid. Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride. Osmotic Diuretics: Mannitol

Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril, Benazepril

hydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,* Clonidine

hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium nitroprusside, Diazoxide,Minoxidil, Reserpine, Hydralazine hydrochloride.

Unit III

Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide hydrochloride, Disopyramide phosphate*, Phenytoin sodium, Lidocaine hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide hydrochloride,

Amiodarone, Sotalol.

Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine and Cholestipol

Coagulant & Anticoagulants: Menadione, Acetomenadione, Warfarin*, Anisindione, clopidogrel

Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide, Bosentan, Tezosentan.

Unit IV

Drugs acting on Endocrine system

Nomenclature, Stereochemistry and metabolism of steroids

Sex hormones: Testosterone, Nandralone, Progestrones, Oestriol, Oestradiol, Oestrione, Diethyl stilbestrol.

Drugs for erectile dysfunction: Sildenafil, Tadalafil.

Oral contraceptives: Mifepristone, Norgestril, Levonorgestrol

Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone, Dexamethasone

Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil, Methimazole.

Unit V

Antidiabetic agents:

Insulin and its preparations

Sulfonyl ureas: Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride. Biguanides: Metformin.

Thiazolidinediones: Pioglitazone, Rosiglitazone.

Meglitinides: Repaglinide, Nateglinide.

Glucosidase inhibitors: Acrabose, Voglibose.

Local Anesthetics: SAR of Local anesthetics

Benzoic Acid derivatives; Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine.

Amino Benzoic acid derivatives: Benzocaine*, Butamben, Procaine*, Butacaine,

Propoxycaine, Tetracaine, Benoxinate.

Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine, Etidocaine.

Miscellaneous: Phenacaine, Diperodon, Dibucaine.*

 

Subject: INDUSTRIAL PHARMACY

Theory Practical
Unit I

Preformulation Studies: Introduction to preformulation, goals and objectives, study of

physicochemical characteristics of drug substances.

a. Physical properties: Physical form (crystal & amorphous), particle size, shape, flow

properties, solubility profile (pKa, pH, partition coefficient), polymorphism

b. Chemical Properties: Hydrolysis, oxidation, reduction, racemisation, polymerization

BCS classification of drugs & its significant

Application of preformulation considerations in the development of solid, liquid oral and

parenteral dosage forms and its impact on stability of dosage forms.

Unit II

Tablets:

a. Introduction, ideal characteristics of tablets, classification of tablets. Excipients, Formulation of tablets, granulation methods, compression and processing problems.

Equipments and tablet tooling.

b. Tablet coating: Types of coating, coating materials, formulation of coating composition, methods of coating, equipment employed and defects in coating.

c. Quality control tests: In process and finished product tests

Liquid orals: Formulation and manufacturing consideration of syrups and elixirs suspensions and emulsions; Filling and packaging; evaluation of liquid orals official in pharmacopoeia

Unit III

Capsules:

a. Hard gelatin capsules: Introduction, Production of hard gelatin capsule shells. Size of capsules, Filling, finishing and special techniques of formulation of hard gelatine capsules, manufacturing defects. In process and final product quality control tests for capsules.

b. Soft gelatin capsules: Nature of shell and capsule content, size of capsules,importance of base adsorption and minim/gram factors, production, in process and final product quality control tests. Packing, storage and stability testing of soft gelatin capsules and their applications.

Pellets: Introduction, formulation requirements, pelletization process, equipments for manufacture of pellets

Unit IV

Parenteral Products:

a. Definition, types, advantages and limitations. Preformulation factors and essential equirements, vehicles, additives, importance of isotonicity

b. Production procedure, production facilities and controls, aseptic processing

c. Formulation of injections, sterile powders, large volume parenterals and lyophilized products.

d. Containers and closures selection, filling and sealing of ampoules, vials and infusion fluids. Quality control tests of parenteral products.

Ophthalmic Preparations: Introduction, formulation considerations; formulation of eye

drops, eye ointments and eye lotions; methods of preparation; labeling, containers; evaluation of ophthalmic preparations

Unit V

Cosmetics: Formulation and preparation of the following cosmetic preparations: lipsticks, shampoos, cold cream and vanishing cream, tooth pastes, hair dyes and sunscreens.

Pharmaceutical Aerosols: Definition, propellants, containers, valves, types of aerosol systems; formulation and manufacture of aerosols; Evaluation of aerosols; Quality control and stability studies.

Packaging Materials Science: Materials used for packaging of pharmaceutical products, factors influencing choice of containers, legal and official requirements for containers, stability aspects of packaging materials, quality control tests.

1. Preformulation studies on paracetamol/asparin/or any other drug

 

2. Preparation and evaluation of Paracetamol tablets

 

3. Preparation and evaluation of Aspirin tablets

 

4. Coating of tablets- film coating of tables/granules

 

5. Preparation and evaluation of Tetracycline capsules

 

6. Preparation of Calcium Gluconate injection

 

7. Preparation of Ascorbic Acid injection

 

8. Qulaity control test of (as per IP) marketed tablets and capsules

 

9. Preparation of Eye drops/ and Eye ointments

 

10. Preparation of Creams (cold / vanishing cream)

 

11. Evaluation of Glass containers (as per IP)

]’]999 

Subject: PHARMACOLOGY-II

Theory Practical
Unit I

1. Pharmacology of drugs acting on cardio vascular system

a. Introduction to hemodynamic and electrophysiology of heart.

b. Drugs used in congestive heart failure

c. Anti-hypertensive drugs.

d. Anti-anginal drugs.

e. Anti-arrhythmic drugs.

f. Anti-hyperlipidemic drugs.

Unit II

1. Pharmacology of drugs acting on cardio vascular system

a. Drug used in the therapy of shock.

b. Hematinics, coagulants and anticoagulants.

c. Fibrinolytics and anti-platelet drugs

d. Plasma volume expanders

2. Pharmacology of drugs acting on urinary system

a. Diuretics

b. Anti-diuretics.

Unit III

3. Autocoids and related drugs

a. Introduction to autacoids and classification

b. Histamine, 5-HT and their antagonists.

c. Prostaglandins, Thromboxanes and Leukotrienes.

d. Angiotensin, Bradykinin and Substance P.

e. Non-steroidal anti-inflammatory agents

f. Anti-gout drugs

g. Antirheumatic drugs

Unit IV

5. Pharmacology of drugs acting on endocrine system

a. Basic concepts in endocrine pharmacology.

b. Anterior Pituitary hormones- analogues and their inhibitors.

c. Thyroid hormones- analogues and their inhibitors.

d. Hormones regulating plasma calcium level- Parathormone, Calcitonin and

Vitamin-D.

d. Insulin, Oral Hypoglycemic agents and glucagon.

e. ACTH and corticosteroids.

Unit V

5. Pharmacology of drugs acting on endocrine system

a. Androgens and Anabolic steroids.

b. Estrogens, progesterone and oral contraceptives.

c. Drugs acting on the uterus.

6. Bioassay

a. Principles and applications of bioassay.

b. Types of bioassay

c. Bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine and 5-HT.

1. Introduction to in-vitro pharmacology and physiological salt solutions.

 

2. Effect of drugs on isolated frog heart.

 

3. Effect of drugs on blood pressure and heart rate of dog.

 

4. Study of diuretic activity of drugs using rats/mice.

 

5. DRC of acetylcholine using frog rectus abdominis muscle.

 

6. Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively.

 

 

7. Bioassay of histamine using guinea pig ileum by matching method.

 

8. Bioassay of oxytocin using rat uterine horn by interpolation method.

 

9. Bioassay of serotonin using rat fundus strip by three point bioassay.

 

10. Bioassay of acetylcholine using rat ileum/colon by four point bioassay.

 

11. Determination of PA2 value of prazosin using rat anococcygeus muscle (by Schilds plot method).

 

12. Determination of PD2 value using guinea pig ileum.

 

13. Effect of spasmogens and spasmolytics using rabbit jejunum.

 

14. Anti-inflammatory activity of drugs using carrageenan induced paw-edema model.

 

15. Analgesic activity of drug using central and peripheral methods

 

Note: All laboratory techniques and animal experiments are demonstrated by simulated

experiments by softwares and videos

 

Subject: PHARMACOGNOSY AND PHYTOCHEMISTRY II

Theory Practical
Unit I

Metabolic pathways in higher plants and their determination

a) Brief study of basic metabolic pathways and formation of different secondary metabolites

through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway.

b) Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.

Unit II

General introduction, composition, chemistry & chemical classes, biosources, therapeutic

uses and commercial applications of following

secondary metabolites:

Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,

Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta

Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis

Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander

Tannins: Catechu, Pterocarpus

Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony

Glycosides: Senna, Aloes, Bitter Almond

Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids

Unit III

Isolation, Identification and Analysis of Phytoconstituents

a) Terpenoids: Menthol, Citral, Artemisin

b) Glycosides: Glycyrhetinic acid & Rutin

c) Alkaloids: Atropine, Quinine, Reserpine, Caffeine

d) Resins: Podophyllotoxin, Curcumin

Unit IV

Industrial production, estimation and utilization of the following phytoconstituents: Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine

Unit V

Basics of Phytochemistry

Modern methods of extraction, application of latest techniques like Spectroscopy,

chromatography and electrophoresis in the isolation, purification and identification of crude

drugs

1. Morphology, histology and powder characteristics & extraction & detection of:

Cinchona, Cinnamon, Senna, Clove, Ephedra, Fennel and Coriander

 

 

2. Exercise involving isolation & detection of active principles

a. Caffeine – from tea dust.

b. Diosgenin from Dioscorea

c. Atropine from Belladonna

d. Sennosides from Senna

 

3. Separation of sugars by Paper chromatography

4. TLC of herbal extract

 

5. Distillation of volatile oils and detection of phytoconstitutents by TLC

 

6. Analysis of crude drugs by chemical tests: (i) Asafoetida (ii) Benzoin (iii)

Colophony (iv) Aloes (v) Myrrh

 

Subject: PHARMACEUTICAL JURISPRUDENCE

Theory
Unit I

Drugs and Cosmetics Act, 1940 and its rules 1945:

Objectives, Definitions, Legal definitions of schedules to the Act and Rules

Import of drugs – Classes of drugs and cosmetics prohibited from import, Import under license or permit. Offences and penalties.

Manufacture of drugs – Prohibition of manufacture and sale of certain drugs,

Conditions for grant of license and conditions of license for manufacture of drugs,

Manufacture of drugs for test, examination and analysis, manufacture of new drug, loan

license and repacking license.

Unit II

Drugs and Cosmetics Act, 1940 and its rules 1945.

Detailed study of Schedule G, H, M, N, P,T,U, V, X, Y, Part XII B, Sch F & DMR (OA)

Sale of Drugs – Wholesale, Retail sale and Restricted license. Offences and penalties

Labeling & Packing of drugs- General labeling requirements and specimen labels for

drugs and cosmetics, List of permitted colors. Offences and penalties.

Administration of the Act and Rules – Drugs Technical Advisory Board, Central drugs

Laboratory, Drugs Consultative Committee, Government drug analysts, Licensing

authorities, controlling authorities, Drugs Inspectors

Unit III

· Pharmacy Act –1948: Objectives, Definitions, Pharmacy Council of India; its

constitution and functions, Education Regulations, State and Joint state pharmacy

councils; constitution and functions, Registration of Pharmacists, Offences and Penalties

· Medicinal and Toilet Preparation Act –1955: Objectives, Definitions, Licensing,

Manufacture In bond and Outside bond, Export of alcoholic preparations,

Manufacture of Ayurvedic, Homeopathic, Patent & Proprietary Preparations. Offences and Penalties.

· Narcotic Drugs and Psychotropic substances Act-1985 and Rules: Objectives,

Definitions, Authorities and Officers, Constitution and Functions of narcotic &

Psychotropic Consultative Committee, National Fund for Controlling the Drug

Abuse, Prohibition, Control and Regulation, opium poppy cultivation and production

of poppy straw, manufacture, sale and export of opium, Offences and Penalties

Unit IV

· Study of Salient Features of Drugs and Magic Remedies Act and its

rules: Objectives, Definitions, Prohibition of certain advertisements, Classes of

Exempted advertisements, Offences and Penalties

· Prevention of Cruelty to animals Act-1960: Objectives, Definitions, Institutional

Animal Ethics Committee, CPCSEA guidelines for Breeding and Stocking of

Animals, Performance of Experiments, Transfer and acquisition of animals for

experiment, Records, Power to suspend or revoke registration, Offences and Penalties

· National Pharmaceutical Pricing Authority: Drugs Price Control Order (DPCO)-

2013. Objectives, Definitions, Sale prices of bulk drugs, Retail price of formulations,

Retail price and ceiling price of scheduled formulations, National List of Essential

Medicines (NLEM)

Unit V

· Pharmaceutical Legislations – A brief review, Introduction, Study of drugs enquiry

committee, Health survey and development committee, Hathi committee and Mudaliar committee

· Code of Pharmaceutical ethics D efinition, Pharmacist in relation to his job, trade,

medical profession and his profession, Pharmacist’s oath

· Medical Termination of Pregnancy Act

· Right to Information Act

· Introduction to Intellectual Property Rights (IPR)

 

 

 

 

B Pharm Subjects for Semester 6

 

Subjects Theory Practical
Hours Marks Hours Marks
MEDICINAL CHEMISTRY-III 45 100 4/week 50
PHARMACOLOGY-III 45 100 4/week 50
HERBAL DRUG TECHNOLOGY 45 100 4/week 50
BIOPHARMACEUTICS AND PHARMACOKINETICS 45 100
PHARMACEUTICAL BIOTECHNOLOGY 45 100
PHARMACEUTICAL QUALITY ASSURANCE 45 100
   
Total marks 750

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

B pharmacy Syllabus for Semester 6

Subject: MEDICINAL CHEMISTRY – III

Theory Practical
Unit I

Antibiotics

Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.

β-Lactam antibiotics: Penicillin, Cepholosporins, β- Lactamase inhibitors,

Monobactams

Aminoglycosides: Streptomycin, Neomycin, Kanamycin

Tetracyclines: Tetracycline,Oxytetracycline, Chlortetracycline, Minocycline, Doxycyclin

Unit II

Antibiotics

Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.

Macrolide: Erythromycin Clarithromycin, Azithromycin.

Miscellaneous: Chloramphenicol*, Clindamycin.

Prodrugs: Basic concepts and application of prodrugs design.

Antimalarials: Etiology of malaria.

Quinolines: SAR, Quinine sulphate, Chloroquine*, Amodiaquine,

Primaquine phosphate, Pamaquine*, Quinacrine hydrochloride, Mefloquine.

Biguanides and dihydro triazines: Cycloguanil pamoate, Proguanil.

Miscellaneous: Pyrimethamine, Artesunete, Artemether, Atovoquone.

Unit III

Anti-tubercular Agents

Synthetic anti tubercular agents: Isoniozid*, Ethionamide, Ethambutol, Pyrazinamide, Para amino salicylic acid.*

Anti tubercular antibiotics: Rifampicin, Rifabutin, Cycloserine Streptomycine, Capreomycin sulphate.

Urinary tract anti-infective agents

Quinolones: SAR of quinolones, Nalidixic Acid,Norfloxacin, Enoxacin, Ciprofloxacin*, Ofloxacin, Lomefloxacin, Sparfloxacin, Gatifloxacin, Moxifloxacin

Miscellaneous: Furazolidine, Nitrofurantoin*, Methanamine.

Antiviral agents:

Amantadine hydrochloride, Rimantadine hydrochloride, Idoxuridine trifluoride, Acyclovir*, Gancyclovir, Zidovudine, Didanosine, Zalcitabine, Lamivudine, Loviride, Delavirding, Ribavirin, Saquinavir, Indinavir,

Ritonavir.

Unit IV

Antifungal agents:

Antifungal antibiotics: Amphotericin-B, Nystatin, Natamycin, Griseofulvin.

Synthetic Antifungal agents: Clotrimazole, Econazole, Butoconazole, Oxiconazole Tioconozole, Miconazole*, Ketoconazole, Terconazole, Itraconazole, Fluconazole, Naftifine hydrochloride, Tolnaftate*.

Anti-protozoal Agents: Metronidazole*, Tinidazole, Ornidazole, Diloxanide, Iodoquinol, Pentamidine Isethionate, Atovaquone, Eflornithine.

Anthelmintics: Diethylcarbamazine citrate*, Thiabendazole, Mebendazole*,

Albendazole, Niclosamide, Oxamniquine, Praziquantal, Ivermectin.

Sulphonamides and Sulfones

Historical development, chemistry, classification and SAR of Sulfonamides:

Sulphamethizole, Sulfisoxazole, Sulphamethizine, Sulfacetamide*, Sulphapyridine, Sulfamethoxaole*, Sulphadiazine, Mefenide acetate, Sulfasalazine.

Folate reductase inhibitors: Trimethoprim*, Cotrimoxazole.

Sulfones: Dapsone*.

Unit V

Introduction to Drug Design

Various approaches used in drug design.

Physicochemical parameters used in quantitative structure activity relationship (QSAR) such as partition coefficient, Hammet’s electronic

parameter, Tafts steric parameter and Hansch analysis. Pharmacophore modeling and docking techniques.

Combinatorial Chemistry: Concept and applications chemistry: solid phase and solution phase synthesis.

I Preparation of drugs and intermediates

1 Sulphanilamide

2 7-Hydroxy, 4-methyl coumarin

3 Chlorobutanol

4 Triphenyl imidazole

5 Tolbutamide

6 Hexamine

 

II Assay of drugs

1 Isonicotinic acid hydrazide

2 Chloroquine

3 Metronidazole

4 Dapsone

5 Chlorpheniramine maleate

6 Benzyl penicillin

 

III Preparation of medicinally important compounds or intermediates by Microwave irradiation technique

 

IV Drawing structures and reactions using chem draw®

 

V Determination of physicochemical properties such as logP, clogP, MR, Molecular weight, Hydrogen bond donors and acceptors for class of drugs course content using drug design software Drug likeliness screening (Lipinskies RO5)

 

B Pharm Subject: PHARMACOLOGY-III

Theory Practical
Unit I

1. Pharmacology of drugs acting on Respiratory system

a. Anti -asthmatic drugs

b. Drugs used in the management of COPD

c. Expectorants and antitussives

d. Nasal decongestants

e. Respiratory stimulants

2. Pharmacology of drugs acting on the Gastrointestinal Tract

a. Antiulcer agents.

b. Drugs for constipation and diarrhoea.

c. Appetite stimulants and suppressants.

d. Digestants and carminatives.

e. Emetics and anti-emetics.

Unit II

3. Chemotherapy

a. General principles of chemotherapy.

b. Sulfonamides and cotrimoxazole.

c. Antibiotics- Penicillins, cephalosporins, chloramphenicol, macrolides, quinolones and fluoroquinolins, tetracycline and aminoglycosides.

Unit III

3. Chemotherapy

a. Antitubercular agents

b. Antileprotic agents

c. Antifungal agents

d. Antiviral drugs

e.Anthelmintics

f. Antimalarial drugs

g. Antiamoebic agents

Unit IV

3. Chemotherapy

l. Urinary tract infections and sexually transmitted diseases.

m. Chemotherapy of malignancy.

4. Immunopharmacology

a. Immunostimulants

b. Immunosuppressant

Protein drugs, monoclonal antibodies, target drugs to antigen, biosimilars

Unit V

5. Principles of toxicology

a. Definition and basic knowledge of acute, subacute and chronic toxicity.

b. Definition and basic knowledge of genotoxicity, carcinogenicity, teratogenicity and mutagenicity

c. General principles of treatment of poisoning

d. Clinical symptoms and management of barbiturates, morphine, organophosphosphorus compound and lead, mercury and arsenic poisoning.

6. Chronopharmacology

a. Definition of rhythm and cycles.

b. Biological clock and their significance leading to chronotherapy.

1. Dose calculation in pharmacological experiments

 

2. Antiallergic activity by mast cell stabilization assay

 

3. Study of anti-ulcer activity of a drug using pylorus ligand (SHAY) rat model and NSAIDS induced ulcer model.

 

4. Study of effect of drugs on gastrointestinal motility

 

5. Effect of agonist and antagonists on guinea pig ileum

 

6. Estimation of serum biochemical parameters by using semi- auto analyser

 

7. Effect of saline purgative on frog intestine

 

8. Insulin hypoglycemic effect in rabbit

 

9. Test for pyrogens ( rabbit method)

 

10. Determination of acute oral toxicity (LD50) of a drug from a given data

 

11. Determination of acute skin irritation / corrosion of a test substance

 

12. Determination of acute eye irritation / corrosion of a test substance

 

13. Calculation of pharmacokinetic parameters from a given data

 

14. Biostatistics methods in experimental pharmacology( student’s t test, ANOVA)

 

 

15. Biostatistics methods in experimental pharmacology (Chi square test, Wilcoxon

Signed Rank test)

 

*Experiments are demonstrated by simulated experiments/videos

 

 

Subject: HERBAL DRUG TECHNOLOGY

Theory Practical
Unit I

Herbs as raw materials

Definition of herb, herbal medicine, herbal medicinal product, herbal drug preparation.

Source of Herbs

Selection, identification and authentication of herbal materials.

Processing of herbal raw material

Biodynamic Agriculture

Good agricultural practices in cultivation of medicinal plants including Organic farming.

Pest and Pest management in medicinal plants: Biopesticides/Bioinsecticides.

Indian Systems of Medicine

a) Basic principles involved in Ayurveda, Siddha, Unani and Homeopathy.

b) Preparation and standardization of Ayurvedic formulations viz Aristas and Asawas, Ghutika,Churna, Lehya and Bhasma.

Unit II

Nutraceuticals

General aspects, Market, growth, scope and types of products available in the market. Health benefits and role of Nutraceuticals in ailments like Diabetes, CVS diseases, Cancer, Irritable bowel syndrome and various Gastro intestinal diseases.

Study of following herbs as health food: Alfaalfa, Chicory, Ginger, Fenugreek, Garlic, Honey, Amla, Ginseng, Ashwagandha, Spirulina

Herbal-Drug and Herb-Food Interactions: General introduction to interaction and classification. Study of following drugs and their possible side effects and interactions:

Hypercium, kava-kava, Ginkobiloba, Ginseng, Garlic, Pepper & Ephedra.

Unit III

Herbal Cosmetics

Sources and description of raw materials of herbal origin used via, fixed oils, waxes, gums colours, perfumes, protective agents, bleaching agents, antioxidants in products such as skincare, hair care and oral hygiene products.

Herbal excipients:

Herbal Excipients – Significance of substances of natural origin as excipients – colorants, sweeteners, binders, diluents, viscosity builders, disintegrants, flavors & perfumes.

Herbal formulations :

Conventional herbal formulations like syrups, mixtures and tablets and Novel dosage forms like phytosomes

Unit IV

Evaluation of Drugs WHO & ICH guidelines for the assessment of herbal drugs. Stability testing of herbal drugs.

Patenting and Regulatory requirements of natural products:

a) Definition of the terms: Patent, IPR, Farmers right, Breeder’s right, Bioprospecting and Biopiracy

b) Patenting aspects of Traditional Knowledge and Natural Products. Case study of Curcuma & Neem.

Regulatory Issues – Regulations in India (ASU DTAB, ASU DCC), Regulation of manufacture of ASU drugs – Schedule Z of Drugs & Cosmetics Act for ASU drugs.

Unit V

General Introduction to Herbal Industry

Herbal drugs industry: Present scope and future prospects.

A brief account of plant based industries and institutions involved in work on medicinal and aromatic plants in India.

Schedule T – Good Manufacturing Practice of Indian systems of medicine

Components of GMP (Schedule – T) and its objectives

Infrastructural requirements, working space, storage area, machinery and equipments, standard operating procedures, health and hygiene, documentation and records.

1. To perform preliminary phytochemical screening of crude drugs.

 

2. Determination of the alcohol content of Asava and Arista

 

3. Evaluation of excipients of natural origin

 

4. Incorporation of prepared and standardized extract in cosmetic formulations like creams, lotions and shampoos and their evaluation.

 

5. Incorporation of prepared and standardized extract in formulations like syrups, mixtures and tablets and their evaluation as per Pharmacopoeial requirements.

 

6. Monograph analysis of herbal drugs from recent Pharmacopoeias

 

7. Determination of Aldehyde content

 

8. Determination of Phenol content

 

9. Determination of total alkaloids

 

Subject: BIOPHARMACEUTICS AND PHARMACOKINETICS

Theory
Unit I

Introduction to Bio pharmaceutics

Absorption; Mechanisms of drug absorption through GIT, factors influencing drug absorption though GIT, absorption of drug from Non per oral extra-vascular routes, Distribution Tissue permeability of drugs, binding of drugs, apparent, volume of drug distribution, plasma and tissue protein binding of drugs, factors affecting protein-drug binding. Kinetics of protein binding, Clinical significance of protein binding of drugs

Unit II

Elimination: Drug metabolism and basic understanding metabolic pathways renal excretion of drugs, factors affecting renal excretion of drugs, renal clearance, Non renal routes of drug excretion of drugs

Bioavailability and Bioequivalence: Definition and Objectives of bioavailability, absolute and relative bioavailability, measurement of bioavailability, in-vitro drug dissolution models, in-vitroin-vivo correlations, bioequivalence studies, methods to enhance the dissolution rates and bioavailability of poorly soluble drugs.

Unit III

Pharmacokinetics: Definition and introduction to Pharmacokinetics, Compartment models, Non compartment models, physiological models, One compartment open model. (a). Intravenous Injection (Bolus) (b). Intravenous infusion and (c) Extra vascular administrations. Pharmacokinetics parameters – KE ,t1/2,Vd,AUC,Ka, Clt and CLR- definitions methods of eliminations, understanding of their significance and

application

Unit IV

Multicompartment models: Two compartment open model. IV bolus, Kinetics of multiple dosing, steady state drug levels, calculation of loading and maintenance doses and their significance in clinical settings.

Unit V

Nonlinear Pharmacokinetics: a. Introduction, b. Factors causing Non-linearity. c. Michaelis-menton method of estimating parameters, Explanation with example of drugs.

 

Subject: PHARMACEUTICAL BIOTECHNOLOGY

Theory
Unit I

a) Brief introduction to Biotechnology with reference to Pharmaceutical Sciences.

b) Enzyme Biotechnology- Methods of enzyme immobilization and applications.

c) Biosensors- Working and applications of biosensors in Pharmaceutical Industries.

d) Brief introduction to Protein Engineering.

e) Use of microbes in industry. Production of Enzymes- General consideration –

Amylase, Catalase, Peroxidase, Lipase, Protease, Penicillinase.

f) Basic principles of genetic engineering.

Unit II

a) Study of cloning vectors, restriction endonucleases and DNA ligase.

b) Recombinant DNA technology. Application of genetic engineering in medicine.

c) Application of r DNA technology and genetic engineering in the production of:

i) Interferon ii) Vaccines- hepatitis- B iii) Hormones-Insulin.

d) Brief introduction to PCR

Unit III

Types of immunity- humoral immunity, cellular immunity

a) Structure of Immunoglobulins

b) Structure and Function of MHC

c) Hypersensitivity reactions, Immune stimulation and Immune suppressions.

d) General method of the preparation of bacterial vaccines, toxoids, viral vaccine, antitoxins, serum-immune blood derivatives and other products relative to immunity.

e) Storage conditions and stability of official vaccines

f) Hybridoma technology- Production, Purification and Applications

g) Blood products and Plasma Substituties.

Unit IV

a) Immuno blotting techniques- ELISA, Western blotting, Southern blotting.

b) Genetic organization of Eukaryotes and Prokaryotes

c) Microbial genetics including transformation, transduction, conjugation, plasmids and transposons.

d) Introduction to Microbial biotransformation and applications.

e) Mutation: Types of mutation/mutants.

Unit V

a) Fermentation methods and general requirements, study of media, equipments, sterilization methods, aeration process, stirring.

b) Large scale production fermenter design and its various controls.

c) Study of the production of – penicillins, citric acid, Vitamin B12, Glutamic acid, Griseofulvin,

d) Blood Products: Collection, Processing and Storage of whole human blood, dried human plasma, plasma Substituties.

 

Subject: BP606TPHARMACEUTICAL QUALITY ASSURANCE

Theory
Unit I

Quality Assurance and Quality Management concepts: Definition and concept of Quality

control, Quality assurance and GMP

Total Quality Management (TQM): Definition, elements, philosophies

ICH Guidelines: purpose, participants, process of harmonization, Brief overview of QSEM,

with special emphasis on Q-series guidelines, ICH stability testing guidelines

Quality by design (QbD): Definition, overview, elements of QbD program, tools

ISO 9000 & ISO14000: Overview, Benefits, Elements, steps for registration

NABL accreditation : Principles and procedures

Unit II

Organization and personnel: Personnel responsibilities, training, hygiene and personal records.

Premises: Design, construction and plant layout, maintenance, sanitation, environmental

control, utilities and maintenance of sterile areas, control of contamination.

Equipments and raw materials: Equipment selection, purchase specifications, maintenance, purchase specifications and maintenance of stores for raw materials.

Unit III

Quality Control: Quality control test for containers, rubber closures and secondary packing

materials.

Good Laboratory Practices: General Provisions, Organization and Personnel, Facilities,

Equipment, Testing Facilities Operation, Test and Control Articles, Protocol for Conduct of a Nonclinical Laboratory Study, Records and Reports, Disqualification of Testing Facilities

Unit IV

Complaints: Complaints and evaluation of complaints, Handling of return good, recalling and waste disposal.

Document maintenance in pharmaceutical industry: Batch Formula Record, Master Formula Record, SOP, Quality audit, Quality Review and Quality documentation, Reports and documents, distribution records.

Unit V

Calibration and Validation: Introduction, definition and general principles of calibration,

qualification and validation, importance and scope of validation, types of validation, validation master plan. Calibration of pH meter, Qualification of UV-Visible spectrophotometer, General principles of Analytical method Validation.

Warehousing: Good warehousing practice, materials management

 

 

Pharmacy market demand

Hospitals: In abroad mostly, the Doctors diagnose but the pharmacists decide the medicines and their dosage. Therefore, Pharmacy graduates have an important role in earning attractive remuneration and to occupy strategic positions.

Production and Manufacturing: Professionals for production and manufacturing are not only required by biotechnological products, surgical dressings, medical devices, equipment, ayurvedic/ homoeopathic / Unani medicines, veterinary medicine, etc but also for the requirement for the production of cosmetics, soaps, toiletries and dental products.

Analysis and Testing: Highly skilled staff is required by companies to handle sensitive analytical dealings and sophisticated equipment. Analysis and testing go hand in hand in order to maintain a proper Quality control (QC) and Quality Assurance (QA).

R & D: M. Pharms and Ph.Ds are highly in demand for research of new drugs, process development, formulation, development, clinical trials and Toxicological Studies

Marketing: Sales and marketing are considered to be a highly technical arena and hence one of the best when it comes to perks.

Top 20 B.Pharmacy colleges in Tamil Nadu

Top 20 B.Pharmacy colleges in Tamil Nadu - Chennai Madras TN B Pharm

Title- Top 20 B.Pharmacy colleges in Tamil Nadu

There is lot of requirement in medical industry these days. As there is increase in epidemics, diseases and casualties lot of hospitals require candidates from Pharmacy background. Other than just working in hospitals, pharmacy does offer you job prospects in Pharmaceutical companies where medicines are manufactured.

The Pharmacy is considered as a very reputed and noble course for the medical aspirants. Students who are currently studying Science-Biology can opt for this course to get better future prospects. In terms of both private and government medical sectors, there are enough jobs that are needed to be filled in next 5-6 years.

Through this article, we are bringing some top-notch colleges in Tamil Nadu. These colleges will give you all facilities required to get a successful career in pharmacy. Whether it is bachelors or masters, you will gain lot of experience and knowledge through joining these colleges. These colleges are shortlisted on the basis of MHRD Ratings, UGC Recommendations and Reputation. You can refer to the list to find the dream college of your choice.

B.Pharm Colleges in Tamil Nadu

  1. Anna University Tiruchirapalli- BIT Campus
  2. Madurai Medical College
  3. Annamalai University
  4. Dr MGR Medical University, Chennai
  5. Cherraan’s College of Pharmacy
  6. Adhiparasakthi College of Pharmacy, Kancheepuram
  7. VEL’s University, Chennai
  8. Vinayaka Missions University, Chennai
  9. Texcity Institutions, Coimbatore
  10. SRM University Chennai
  11. JSS University Mysore
  12. JSS College of Pharmacy Ooty
  13. Sri Ramchandra University, Chennai
  14. MOHAMED SATHAK A.J College of Pharmacy, Chennai
  15. Vinanayaka Missions College of Pharmacy, Salem
  16. BS Abdur Rahman Crescent institute of science and Technology, Chennai
  17. KM College of Pharmacy, Madurai
  18. SA Raja Pharmacy College, Tirunelveli
  19. PSG College of Pharmacy, Coimbatore
  20. CL Baid Metha college of Pharmacy, Chennai

The top 20 B.Pharma Colleges in tamil nadu has lot to offer you in terms of better placements and experience to pursue masters or PHD in Pharmacy. These colleges are good for pursuing bachelors, masters and Diploma in Pharmacy. All these colleges offer campus with world class facilities to offer best to the students. We wish you a best of luck for your future ahead.

B. Pharmacy 2nd Year Subjects & Syllabus PDF B Pharm Second Year 3 + 4 Semester

B. Pharmacy 2nd Year Subjects & Syllabus PDF B Pharm Second Year 3 + 4 Semester

B. Pharmacy 2nd Year Subjects and Syllabus

It’s always good to be knowledgeable about the chosen stream chain. The B. Pharm degree is the basic prerequisite for registration to practice as a pharmacist in many countries. In India, as we came to know that the colleges imparting this educational courses(D. Pharm, B. Pharm, M. Pharm or Pharm. D) has to be approved by Pharmacy Council Of India (PCI) or All Indian Council of Technical Education (AICTE). Similarly, outside India countries those are providing these courses are also affiliated with some universities. Let us check out those and spread the information to the students aspiring for the same.

B. Pharmacy 2nd Year Subjects & Syllabus PDF B Pharm Second Year 3 + 4 Semester

Apart from the United States, Canadian universities having B. Pharm programs are Dalhousie University, Memorial University of Newfoundland, University of Manitoba and by the University of Saskatchewan. In Australia, all B. Pharm programs are accredited by the New Zealand and Australian Pharmacy Schools Accreditation Committee (NAPSAC). B. Pharm (Rural) program was offered by the University of Sydney (Camperdown/Darlington campus). Hong Kong provides the Bachelor of Pharmacy course offered by the Chinese University of Hong Kong (CUHK) under the Faculty of Medicine. The Bachelor of Pharmacy degree in Bangladesh is approved by the Pharmacy Council of Bangladesh (PCB).  In Norway, Oslo Metropolitan University, The University of Tromso and Nord University offer the B. Pharm degree. B. Pharm programs in Africa are offered at the National University of Lesotho – Department of Pharmacy, by some Ugandan universities and Kenyan universities too. Many universities in South Africa also accredit B. Pharm programs.

Here we are providing the syllabus of B. Pharm (2nd year). As the lateral entry on the third semester, candidates on completion approved D. Pharmacy course by Pharmacy Council of India can apply accordingly.

B. Pharmacy Subjects for 2nd year (Semester 3)

Subjects Theory Practical
Hours Marks Hours Marks
PHARMACEUTICAL ORGANIC CHEMISTRY –II 45 100 4/week 50
PHYSICAL PHARMACEUTICS-I 45 100 4/week 50
PHARMACEUTICAL MICROBIOLOGY 45 100 4/week 50
PHARMACEUTICAL ENGINEERING 45 100 4/week 50
   
Total marks 600

 

 

 

B. Pharm Syllabus for Semester 3 Second Year

Subject: PHARMACEUTICAL ORGANIC CHEMISTRY –II

Theory Practical
Unit I

· Benzene and its derivatives

A. Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule

B. Reactions of benzene-nitration, sulphonation, halogenations reactivity,

Friedelcrafts alkylation- reactivity, limitations,

Friedelcrafts acylation.

C. Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.

D. Structure and uses of DDT, Saccharin, BHC and Chloramine

Unit II

· Phenols* – Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol, cresols, resorcinol, naphthols

· Aromatic Amines* – Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts

· Aromatic Acids* –Acidity, effect of substituents on acidity and important reactions of benzoic acid.

Unit III

· Fats and Oils

a.Fatty acids – reactions.

b. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.

c. Analytical constants – Acid value, Saponification value, Ester value,

Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and

principle involved in their determination.

Unit IV

· Polynuclear hydrocarbons:

a. Synthesis, reactions

b. Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivative

Unit V

· Cyclo alkanes*

Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only

I. Experiments involving laboratory techniques

· Recrystallization

· Steam distillation

 

II. Determination of following oil values (including standardization of

reagents)

· Acid value

· Saponification value

· Iodine value

 

III. Preparation of compounds

· Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol

/Aniline by acylation reaction.

· 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/

· Acetanilide by halogenation (Bromination) reaction.

· 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid /

Nitro benzene by nitration reaction.

· Benzoic acid from Benzyl chloride by oxidation reaction.

· Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by

hydrolysis reaction.

· 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling

reactions.

· Benzil from Benzoin by oxidation reaction.

· Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction

· Cinnammic acid from Benzaldehyde by Perkin reaction

· P-Iodo benzoic acid from P-amino benzoic acid

 

Subject: PHYSICAL PHARMACEUTICS-I

Theory Practical
Unit I

Solubility of drugs: Solubility expressions, mechanisms of solute solvent interactions,

ideal solubility parameters, solvation & association, quantitative approach to the factors

influencing solubility of drugs, diffusion principles in biological systems. Solubility

of gas in liquids, solubility of liquids in liquids, (Binary solutions, ideal solutions)

Raoult’s law, real solutions. Partiallymiscible liquids, Critical solution temperature and

applications. Distribution law, its limitations and applications

Unit II

States of Matter and properties of matter:State of matter, changes in the state of matter,

latent heats, vapour pressure, sublimation critical point, eutectic mixtures, gases, aerosols

– inhalers, relative humidity, liquid complexes, liquid crystals, glassy states, solid crystalline,

amorphous & polymorphism.

Physicochemical properties of drug molecules: Refractive index, optical rotation,

dielectric constant, dipole moment, dissociation constant, determinations and applications.

Unit III

Surface and interfacial phenomenon: Liquid interface, surface & interfacial tensions,

surface free energy, measurement of surface & interfacial tensions, spreading coefficient,

adsorption at liquid interfaces, surface active agents, HLB Scale, solubilisation, detergency, adsorption at solid interface.

Unit IV

Complexation and protein binding: Introduction, Classification of Complexation,

Applications, methods of analysis, protein binding, Complexation and drug action,

crystalline structures of complexes and thermodynamic treatment of stability constants

Unit V

pH, buffers and Isotonic solutions: Sorensen’s pH scale, pH determination(electrometric and calorimetric), applications of buffers, buffer equation, buffer capacity, buffers in pharmaceutical and biological systems, buffered isotonic solutions

1. Determination the solubility of drug at room temperature

2. Determination of pKa value by Half Neutralization/ Henderson Hasselbalch

equation.

3. Determination of Partition co- efficient of benzoic acid in benzene and water

4. Determination of Partition co- efficient of Iodine in CCl4 and water

5. Determination of % composition of NaCl in a solution using phenol-water system by CST method

6. Determination of surface tension of given liquids by drop count and drop weight method

7. Determination of HLB number of a surfactant by saponification method

8. Determination of Freundlich and Langmuir constants using activated charcoal

9. Determination of critical micellar concentration of surfactants

10. Determination of stability constant and donor acceptor ratio of PABA-Caffeine complex by solubilitymethod

11. Determination of stability constant and donor acceptor ratio of Cupric-Glycine complex by pH titration method

 

Subject: PHARMACEUTICAL MICROBIOLOGY

Theory Practical
Unit I

Introduction, history of microbiology, its branches, scope and its

importance.

Introduction to Prokaryotes and Eukaryotes

Study of ultra-structure and morphological classification of bacteria,

nutritional requirements, raw materials used for culture media and physical

parameters for growth, growth curve, isolation and preservation methods

for pure cultures, cultivation of anaerobes, quantitative measurement of

bacterial growth (total & viable count).

Study of different types of phase constrast microscopy, dark field

microscopy and electron microscopy.

Unit II

Identification of bacteria using staining techniques (simple, Gram’s &Acid

fast staining) and biochemical tests (IMViC).

Study of principle, procedure, merits, demerits and applications of physical,chemical gaseous,radiation and mechanical method of sterilization, Evaluation of the efficiency of sterilization methods, Equipments employed in large scale sterilization, Sterility indicators

Unit III

Study of morphology, classification, reproduction/replication and cultivation of Fungi and Viruses.

Classification and mode of action of disinfectants, Factors influencing disinfection, antiseptics and their evaluation. For

bacteriostatic and bactericidal actions

Evaluation of bactericidal & Bacteriostatic.

Sterility testing of products (solids, liquids, ophthalmic and other sterile products) according to IP, BP and USP

Unit IV

Designing of aseptic area, laminar flow equipments; study of different sources of contamination in an aseptic area and methods of prevention, clean area classification.

Principles and methods of different microbiological assay. Methods for

standardization of antibiotics, vitamins and amino acids.

Assessment of a new antibiotic.

Unit V

Types of spoilage, factors affecting the microbial spoilage of pharmaceutical products, sources and types of microbial contaminants,

assessment of microbial contamination and spoilage.

Preservation of pharmaceutical products using antimicrobial agents, evaluation of microbial stability of formulations.

Growth of animal cells in culture, general procedure for cell culture, Primary, established and transformed cell cultures.

Application of cell cultures in pharmaceutical industry and research.

1. Introduction and study of different equipments and processing, e.g., B.O.D. incubator, laminar flow, aseptic hood, autoclave, hot air sterilizer, deep freezer, refrigerator, microscopes used in experimental microbiology.

 

2. Sterilization of glassware, preparation and sterilization of media.

 

3. Sub culturing of bacteria and fungus. Nutrient stabs and slants preparations.

 

4. Staining methods- Simple, Grams staining and acid fast staining (Demonstration with practical).

 

5. Isolation of pure culture of micro-organisms by multiple streak plate technique and other techniques.

 

6. Microbiological assay of antibiotics by cup plate method and other methods

 

7. Motility determination by Hanging drop method.

 

8. Sterility testing of pharmaceuticals.

 

9. Bacteriological analysis of water

 

10. Biochemical test.

 

Subject: PHARMACEUTICAL ENGINEERING

Theory Practical
Unit I

· Flow of fluids: Types of manometers, Reynolds number and its significance,

Bernoulli’s theorem and its applications, Energy losses, Orifice meter, Venturimeter, Pitot tube and Rotometer.

· Size Reduction: Objectives, Mechanisms & Laws governing size reduction, factors affecting size reduction, principles, construction, working, uses, merits and demerits of Hammer mill, ball mill, fluid energy mill, Edge runner mill & end runner mill.

· Size Separation: Objectives, applications & mechanism of size separation,official standards of powders, sieves, size separation Principles, construction, working, uses, merits and demerits of Sieve shaker, cyclone separator, Air separator, Bag filter & elutriation tank microscopy, dark field microscopy and electron microscopy.

Unit II

· Heat Transfer: Objectives, applications & Heat transfer mechanisms. Fourier’s law, Heat transfer by conduction, convection & radiation. Heat interchangers & heat exchangers.

· Evaporation: Objectives, applications and factors influencing evaporation, differences between evaporation and other heat process. principles, construction, working, uses, merits and demerits of Steam jacketed kettle, horizontal tube evaporator, climbing film evaporator, forced circulation evaporator, multiple effect evaporator& Economy of multiple effect evaporator.

· Distillation: Basic Principles and methodology of simple distillation,flash

distillation, fractional distillation, distillation under reduced pressure, steam distillation & molecular distillation

Unit III

· Drying: Objectives, applications & mechanism of drying process, measurements

& applications of Equilibrium Moisture content, rate of drying curve. principles,

construction, working, uses, merits and demerits of Tray dryer, drum dryer spray dryer, fluidized bed dryer, vacuum dryer, freeze dryer.

· Mixing: Objectives, applications & factors affecting mixing, Difference between

solid and liquid mixing, mechanism of solid mixing, liquids mixing and semisolids mixing. Principles, Construction, Working, uses, Merits and Demerits of Double cone blender, twin shell blender, ribbon blender, Sigma blade mixer,

planetarymixers, Propellers, Turbines, Paddles & Silverson Emulsifier

Unit IV

· Filtration: Objectives, applications, Theories & Factors influencing filtration, filter aids, filter medias. Principle, Construction, Working, Uses, Merits and demerits of plate & frame filter, filter leaf, rotary drum filter, Meta filter &

Cartridge filter, membrane filters and Seidtz filter.

· Centrifugation: Objectives, principle & applications of Centrifugation, principles, construction, working, uses, merits and demerits of Perforated basket centrifuge, Non-perforated basket centrifuge, semi continuous centrifuge & super centrifuge.

Unit V

· Materials of pharmaceutical plant construction, Corrosion and its prevention: Factors affecting during materials selected for Pharmaceutical plant construction, Theories of corrosion, types of corrosion and there prevention.

Ferrous and nonferrous metals, inorganic and organic non metals, basic of material handling systems.

I. Determination of radiation constant of brass, iron, unpainted and painted glass.

 

II. Steam distillation – To calculate the efficiency of steam distillation.

 

III. To determine the overall heat transfer coefficient by heat exchanger.

 

IV. Construction of drying curves (for calcium carbonate and starch).

 

V. Determination of moisture content and loss on drying.

 

VI. Determination of humidity of air – i) From wet and dry bulb temperatures –use of Dew point method.

 

VII. Description of Construction working and application of Pharmaceutical

Machinery such as rotary tablet machine, fluidized bed coater, fluid energy mill,

de humidifier.

 

VIII. Size analysis by sieving – To evaluate size distribution of tablet granulations – Construction of various size frequency curves including arithmetic and logarithmic probability plots.

 

IX. Size reduction: To verify the laws of size reduction using ball mill and

determining Kicks, Rittinger’s, Bond’s coefficients, power requirement and

critical speed of Ball Mill.

 

X. Demonstration of colloid mill, planetary mixer, fluidized bed dryer, freeze dryer and such other major equipment.

 

XI. Factors affecting Rate of Filtration and Evaporation (Surface area, Concentration and Thickness/ viscosity)

 

XII. To study the effect of time on the Rate of Crystallization.

 

XIII. To calculate the uniformity Index for given sample by using Double Cone

Blender.

 

 

 

 

 

B. Pharmacy Subjects for Semester 4

 

Subjects Theory Practical
Hours Marks Hours Marks
PHARMACEUTICAL ORGANIC CHEMISTRY –III 45 100
MEDICINAL CHEMISTRY – I 45 100 4/week 50
PHYSI CAL PHARMACEUTICS -II 45 100 3/week 50
PHARMACOLOGY-I 45 100 4/week 50
PHARMACOGNOSY AND PHYTOCHEMISTRY I 45 100 4/week 50
   
Total marks 700

 

 

B. Pharmacy Second Year Syllabus for Semester 4

 

Subject: PHARMACEUTICAL ORGANIC CHEMISTRY –III

Theory
Unit I

Stereo isomerism

Optical isomerism –Optical activity, enantiomerism, diastereoisomerism, meso compounds, Elements of symmetry, chiral and achiral molecules, DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers, Reactions of chiral molecules, Racemic modification and resolution of racemic mixture.

Unit II

Geometrical isomerism, Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems), Methods of determination of configuration of geometrical isomers. Conformational isomerism in Ethane, n-Butane and Cyclohexane, Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity. Stereospecific and stereoselective reactions

Unit III

Heterocyclic compounds:

Nomenclature and classification, Synthesis, reactions and medicinal uses of following compounds/derivatives, Pyrrole, Furan, and Thiophene, Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene

Unit IV

Synthesis, reactions and medicinal uses of following compounds/derivatives.

Pyrazole, Imidazole, Oxazole and Thiazole.

Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine, Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives

Unit V

Reactions of synthetic importance

Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch reduction, Wolff Kishner reduction. Oppenauer-oxidation and Dakin reaction. Beckmanns rearrangement and Schmidt rearrangement. Claisen-Schmidt condensation

 

 

 

 

 

 

 

 

Subject: MEDICINAL CHEMISTRY – I

Theory Practical
Unit I

Introduction to Medicinal Chemistry, History and development of medicinal chemistry, Physicochemical properties in relation to biological action

Unit II

Drugs acting on Autonomic Nervous System, Adrenergic Neurotransmitters:

Biosynthesis and catabolism of catecholamine. Adrenergic receptors (Alpha & Beta) and their distribution.

Sympathomimetic agents: SAR of Sympathomimetic agents

 · Direct acting:

Nor-epinephrine, Epinephrine, Phenylephrine*, Dopamine, Methyldopa, Clonidine, Dobutamine, Isoproterenol, Terbutaline, Salbutamol*, Bitolterol, Naphazoline, Oxymetazoline and Xylometazoline.

· Indirect acting agents: Hydroxyamphetamine, Pseudoephedrine,

Propylhexedrine.

· Agents with mixed mechanism: Ephedrine, Metaraminol.

Adrenergic Antagonists:

Alpha adrenergic blockers: Tolazoline*, Phentolamine,

Phenoxybenzamine, Prazosin, Dihydroergotamine, Methysergide.

Beta adrenergic blockers: SAR of beta blockers, Propranolol*,

Metibranolol, Atenolol, Betazolol, Bisoprolol, Esmolol, Metoprolol,

Labetolol, Carvedilol.

Unit III

Cholinergic neurotransmitters:

Biosynthesis and catabolism of acetylcholine.

Cholinergic receptors (Muscarinic & Nicotinic) and their distribution.

Parasympathomimetic agents: SAR of Parasympathomimetic agents

Direct acting agents: Acetylcholine, Carbachol*, Bethanechol,

Methacholine, Pilocarpine.

Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible):

Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride,

Tacrine hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate

iodide, Parathione, Malathion.

Cholinesterase reactivator: Pralidoxime chloride.

Cholinergic Blocking agents: SAR of cholinolytic agents, Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine sulphate, Scopolamine hydrobromide, Homatropine hydrobromide,

Ipratropium bromide*.

Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate

hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*,

Glycopyrrolate, Methantheline bromide, Propantheline bromide, Benztropine mesylate, Orphenadrine citrate, Biperidine hydrochloride, Procyclidine hydrochloride*, Tridihexethyl chloride, Isopropamide iodide,

Ethopropazine hydrochloride.

Unit IV

Drugs acting on Central Nervous System

A. Sedatives and Hypnotics:

Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*,

Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidem

Barbiturtes: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital,

Amobarbital, Butabarbital, Pentobarbital, Secobarbital

Miscelleneous:

Amides & imides: Glutethmide.

Alcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol.

Aldehyde & their derivatives: Triclofos sodium, Paraldehyde.

B. Antipsychotics

Phenothiazeines: SAR of Phenothiazeines – Promazine hydrochloride,

Chlorpromazine hydrochloride*, Triflupromazine, Thioridazine

hydrochloride, Piperacetazine hydrochloride, Prochlorperazine maleate,

Trifluoperazine hydrochloride.

Ring Analogues of Phenothiazeines: Chlorprothixene, Thiothixene,

Loxapine succinate, Clozapine.

Fluro buterophenones: Haloperidol, Droperidol, Risperidone.

Beta amino ketones: Molindone hydrochloride.

Benzamides: Sulpieride.

C. Anticonvulsants: SAR of Anticonvulsants, mechanism of anticonvulsant action

Barbiturates: Phenobarbitone, Methabarbital. Hydantoins:

Phenytoin*, Mephenytoin, Ethotoin Oxazolidine diones:

Trimethadione, Paramethadione Succinimides:

Phensuximide, Methsuximide, Ethosuximide* Urea and

monoacylureas: Phenacemide, Carbamazepine*

Benzodiazepines: Clonazepam

Miscellaneous: Primidone, Valproic acid , Gabapentin, Felbamate

Unit V

General anesthetics:

Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Sevoflurane, Isoflurane, Desflurane.

Ultra short acting barbitutrates: Methohexital sodium*, Thiamylal sodium, Thiopental sodium.

Dissociative anesthetics: Ketamine hydrochloride.*

Narcotic and non-narcotic analgesics

Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate, Codeine, Meperidine hydrochloride, Anilerdine hydrochloride,

Diphenoxylate hydrochloride, Loperamide hydrochloride, Fentanyl citrate*,

Methadone hydrochloride*, Propoxyphene hydrochloride, Pentazocine, Levorphanol tartarate.

Narcotic antagonists: Nalorphine hydrochloride, Levallorphan tartarate,

Naloxone hydrochloride.

Anti-inflammatory agents: Sodium salicylate, Aspirin, Mefenamic acid*,

Meclofenamate, Indomethacin, Sulindac, Tolmetin, Zomepriac, Diclofenac,

Ketorolac, Ibuprofen*, Naproxen, Piroxicam, Phenacetin, Acetaminophen, Antipyrine, Phenylbutazone.

I Preparation of drugs/ intermediates

1. 1,3-pyrazole

2. 1,3-oxazole

3. Benzimidazole

4. Benztriazole

5. 2,3- diphenyl quinoxaline

6. Benzocaine

7. Phenytoin

8. Phenothiazine

9. Barbiturate

 

II Assay of drugs

1. Chlorpromazine

2. Phenobarbitone

3. Atropine

4. Ibuprofen

5. Aspirin

6. Furosemide

 

III Determination of Partition coefficient for any two drugs

Subject: PHYSICAL PHARMACEUTICS-II

Theory Practical
Unit I

Colloidal dispersions: Classification of dispersed systems & their general characteristics, size & shapes of colloidal particles, classification of colloids & comparative account of their general properties. Optical, kinetic & electrical properties.

Effect of electrolytes, coacervation, peptization& protective action.

Unit II

Rheology: Newtonian systems, law of flow, kinematic viscosity, effect of temperature,

non-Newtonian systems, pseudoplastic, dilatant, plastic, thixotropy, thixotropy in

formulation, determination of viscosity, capillary, falling Sphere, rotational viscometers

Deformation of solids: Plastic and elastic deformation, Heckel equation, Stress, Strain,

Elastic Modulus.

Unit III

Coarse dispersion: Suspension, interfacial properties of suspended particles, settling in

suspensions, formulation of flocculated and deflocculated suspensions. Emulsions and theories of emulsification, microemulsion and multiple emulsions; Stability of emulsions, preservation of emulsions, rheological properties of emulsions and emulsion formulation by HLB method.

Unit IV

Micromeretics: Particle size and distribution, mean particle size, number and weight

distribution, particle number, methods for determining particle size by different

methods, counting and separation method, particle shape, specific surface, methods for

determining surface area, permeability, adsorption, derived properties of powders,

porosity, packing arrangement, densities, bulkiness & flow properties.

Unit V

Drug stability: Reaction kinetics: zero, pseudo-zero, first & second order, units of basic rate constants, determination of reaction order. Physical and chemical factors influencing the chemical degradation of pharmaceutical product: temperature, solvent, ionic strength, dielectric constant, specific & general acid base catalysis, Simple numerical problems. Stabilization of medicinal agents against common reactions like hydrolysis & oxidation. Accelerated stability testing in expiration dating of pharmaceutical dosage forms. Photolytic degradation and its prevention.

1. Determination of particle size, particle size distribution using sieving method

 

2. Determination of particle size, particle size distribution using Microscopic method

 

3. Determination of bulk density, true density and porosity

 

4. Determine the angle of repose and influence of lubricant on angle of repose

 

5. Determination of viscosity of liquid using Ostwald’s viscometer

 

6. Determination sedimentation volume with effect of different suspending agent

 

7. Determination sedimentation volume with effect of different concentration of single suspending agent

 

8. Determination of viscosity of semisolid by using Brookfield viscometer

 

9. Determination of reaction rate constant first order.

 

10. Determination of reaction rate constant second order

 

11. Accelerated stability studies

Subject: PHARMACOLOGY-I

Theory Practical
Unit I

1. General Pharmacology

a. Introduction to Pharmacology- Definition, historical landmarks and scope of

pharmacology, nature and source of drugs, essential drugs concept and routes of

drug administration, Agonists, antagonists( competitive and non competitive), spare

receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy.

b. Pharmacokinetics- Membrane transport, absorption, distribution, metabolism and

excretion of drugs .Enzyme induction, enzyme inhibition, kinetics of elimination

Unit II

General Pharmacology

a. Pharmacodynamics- Principles and mechanisms of drug action. Receptor theories and classification of receptors, regulation of receptors. drug receptors interactions signal transduction mechanisms, G-protein–coupled receptors, ion channel receptor,

transmembrane enzyme linked receptors, transmembrane JAK-STAT binding

receptor and receptors that regulate transcription factors, dose response relationship, therapeutic index, combined effects of drugs and factors modifying drug action.

b. Adverse drug reactions.

c. Drug interactions (pharmacokinetic and pharmacodynamic)

d. Drug discovery and clinical evaluation of new drugs -Drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and pharmacovigilance.

Unit III

Pharmacology of drugs acting on peripheral nervous system

a. Organization and function of ANS.

b. Neurohumoral transmission,co-transmission and classification of neurotransmitters.

c. Parasympathomimetics, Parasympatholytics, Sympathomimetics, sympatholytics.

d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral).

e. Local anesthetic agents.

f. Drugs used in myasthenia gravis and glaucoma.

Unit IV

Pharmacology of drugs acting on central nervous system

a. Neurohumoral transmission in the C.N.S, special emphasis on importance of various neurotransmitters like with GABA, Glutamate, Glycine, serotonin, dopamine.

b. General anesthetics and pre-anesthetics.

c. Sedatives, hypnotics and centrally acting muscle relaxants.

d. Anti-epileptics

e. Alcohols and disulfiram

Unit V

Pharmacology of drugs acting on central nervous system

a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents, anti-manics and hallucinogens.

b. Drugs used in Parkinsons disease and Alzheimer’s disease.

c. CNS stimulants and nootropics.

d. Opioid analgesics and antagonists

e. Drug addiction, drug abuse, tolerance and dependence.

1. Introduction to experimental pharmacology.

 

2. Commonly used instruments in experimental pharmacology.

 

3. Study of common laboratory animals.

 

4. Maintenance of laboratory animals as per CPCSEA guidelines.

 

5. Common laboratory techniques. Blood withdrawal, serum and plasma separation, anesthetics and euthanasia used for animal studies.

 

6. Study of different routes of drugs administration in mice/rats.

 

7. Study of effect of hepatic microsomal enzyme inducers on the phenobarbitone sleeping time in mice.

 

8. Effect of drugs on ciliary motility of frog oesophagus.

 

9. Effect of drugs on rabbit eye.

 

10. Effects of skeletal muscle. relaxants using rota-rod apparatus.

 

11. Effect of drugs on locomotor activity using actophotometer.

 

12. Anticonvulsant effect of drugs by MES and PTZ method.

 

13. Study of stereotype and anti-catatonic activity of drugs on rats/mice.

 

14. Study of anxiolytic activity of drugs using rats/mice.

 

15. Study of local anesthetics by different methods.

 

Note: All laboratory techniques and animal experiments are demonstrated by simulated experiments by softwares and videos

 

Subject: PHARMACOGNOSY AND PHYTOCHEMISTRY I

Theory Practical
Unit I

Introduction to Pharmacognosy:

(a) Definition, history, scope and development of Pharmacognosy

(b) Sources of Drugs – Plants, Animals, Marine & Tissue culture

(c) Organized drugs, unorganized drugs (dried latex, dried juices, dried extracts, gums and

mucilages, oleoresins and oleo- gum -resins).

Classification of drugs:

Alphabetical, morphological, taxonomical, chemical, pharmacological, chemo and sero

taxonomical classification of drugs

Quality control of Drugs of Natural Origin:

Adulteration of drugs of natural origin. Evaluation by organoleptic, microscopic, physical,

chemical and biological methods and properties.

Quantitative microscopy of crude drugs including lycopodium spore method, leafconstants,

camera lucida and diagrams of microscopic objects to scale with camera lucida.

Unit II

Cultivation, Collection, Processing and storage of drugs of natural origin:

Cultivation and Collection of drugs of natural origin

Factors influencing cultivation of medicinal plants.

Plant hormones and their applications.

Polyploidy, mutation and hybridization with reference to medicinal plants

Conservation of medicinal plants

Unit III

Plant tissue culture:

Historical development of plant tissue culture, types of cultures, Nutritional requirements, growth and their maintenance.

Applications of plant tissue culture in pharmacognosy. Edible vaccines

Unit IV

Pharmacognosy in various systems of medicine:

Role of Pharmacognosy in allopathy and traditional systems of medicine namely, Ayurveda,

Unani, Siddha, Homeopathy and Chinese systems of medicine.

Introduction to secondary metabolites:

Definition, classification, properties and test for identification of Alkaloids, Glycosides,

Flavonoids, Tannins, Volatile oil and Resins.

Unit V

Study of biological source, chemical nature and uses of drugs of natural origin containing

following drugs

Plant Products:

Fibers – Cotton, Jute, Hemp

Hallucinogens, Teratogens, Natural allergens

Primary metabolites:

General introduction, detailed study with respect to chemistry, sources, preparation, evaluation, preservation, storage, therapeutic used and commercial utility as Pharmaceutical

Aids and/or Medicines for the following

Primary metabolites: Carbohydrates: Acacia, Agar, Tragacanth, Honey, Proteins and Enzymes: Gelatin, casein, proteolytic enzymes (Papain, bromelain, serratiopeptidase, urokinase, streptokinase, pepsin).

Lipids(Waxes, fats, fixed oils): Castor oil, Chaulmoogra oil, Wool Fat, Bees Wax

Marine Drugs:

Novel medicinal agents from marine sources

1. Analysis of crude drugs by chemical tests: (i)Tragaccanth (ii) Acacia (iii)Agar (iv)Gelatin (v) starch (vi) Honey (vii) Castor oil

 

2. Determination of stomatal number and index

 

3. Determination of vein islet number, vein islet termination and paliside ratio.

 

4. Determination of size of starch grains, calcium oxalate crystals by eye piece micrometer

 

5. Determination of Fiber length and width

 

6. Determination of number of starch grains by Lycopodium spore method

 

7. Determination of Ash value

 

8. Determination of Extractive values of crude drugs

 

9. Determination of moisture content of crude drugs

 

10. Determination of swelling index and foamingB. Pharmacy 2nd Year Subjects & Syllabus PDF B Pharm Second Year 3 + 4 Semester PDF DOWNLOAD

B. Pharmacy 2nd Year Subjects & Syllabus PDF B Pharm Second Year 3 + 4 Semester PDF DOWNLOAD
Scenario of Pharmacy abroad

In some countries, B. Pharm degree has been superseded by the Doctor of Pharmacy (Pharm. D) and Master of Pharmacy (M. Pharm) degrees. In the United Kingdom B. Pharm is replaced by M. Pharm long back. Pharmacy is taught in University of Helsinki and University of Eastern Finland. M. Pharm is a must in order to be a druggist. In the Republic of Ireland, M. Pharm (Hons) degrees are offered by Trinity College, Dublin, University College Cork, Royal College of Surgeons in Ireland, Dublin. However, in Northern Ireland (which is part of the United Kingdom) M. Pharm degrees (as opposed to BSc or B. Pharm degrees) are offered at Queen’s University Belfast as in the rest of the UK. In Pakistan, Pharm. D is the only Basic Pharmacy Degree (5 years program) awarded by universities approved by Pharmacy Council of Pakistan.

B. Pharmacy 1st Year Subjects & Syllabus – PDF – B. Pharm First Year Semester {Sem 1 + 2}

b-pharmacy-1st-year-subjects-syllabus-pdf-b-pharm-first-year

B. Pharmacy 1st Year Subjects and Syllabus:

B. Pharm(a) also called Bachelor in Pharmacy, is an undergraduate academic degree in the medical field of Pharmacy. In the United States, at Washington State University this degree was granted as the baccalaureate pharmacy degree only, where it has now been superseded by the Pharm. D degree. In India, Pharmacy Council of India (PCI) is responsible to provide Pharmacy graduate level education all over the universities. Hence, it is a statutory body that is regulated by the provisions of the Pharmacy Act, 1948, passed by the Indian Parliament. One is eligible to opt for this course after successfully completing Standard Twelve in science stream with Physics, Chemistry, Maths or Biology as combination subjects. Students of Pharmacy are expected to they perform various experiments preparing new drugs for various diseases as practical knowledge along with the theory part. You are always free to discuss about your queries in the comment section below. Here we are going to know about the first year curriculum.

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Regulations:

  • The total duration of the course- 4 years. Typically the course spread out over 6-8 semesters. Each year consists of 2 semesters ideally. Each semester shall consist of minimum 100 working days.
  • Eligibility- 10+2 passed with Science stream subjects (PCB or PCM) from a recognized board with English as one of the subjects and at least 50% marks is the minimum educational qualification. In some states, it is also compulsory to follow their own additional entrance tests.
  • Entrance Examination: BHU B. Pharma Entrance Examination, GPAT- Graduate Pharmacy Aptitude Test, MHT-CET Maharashtra Common Entrance Test, GCET-Goa Common Entrance Test etc.

Subjects for B Pharm 1st year (Semester 1)

Subjects Theory Practical
Hours Marks Hours Marks
HUMAN ANATOMY AND PHYSIOLOGY-I 45 100 4/week 50
PHARMACEUTICAL ANALYSIS 45 100 4/week 50
PHARMACEUTICS- I 45 100 3/week 50
PHARMACEUTICAL INORGANIC CHEMISTRY 45 100 4/week 50
COMMUNICATION SKILLS* 30 50 2/week 25
REMEDIAL BIOLOGY*/ REMEDIAL MATHEMATICS(Only theory)* 30 50 30 25
 
Total marks 675/725 $/750#

#Applicable ONLY for the students who have studied Mathematics / Physics / Chemistry at HSC and appearing for Remedial Biology (RB) course.

$Applicable ONLY for the students who have studied Physics / Chemistry / Botany / Zoology at HSC and appearing for Remedial Mathematics (RM) course.

* Non University Examination (NUE)

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Syllabus for 1st Semester

Subjects Syllabus
Theory Practical
 

HUMAN ANATOMY AND PHYSIOLOGY-I

Unit I(Introduction to human body, Cellular level of organization, Tissue level of organization); Unit II(Integumentary system, Skeletal system, Joints); Unit III(Body fluids and blood, Lymphatic system); Unit IV(Peripheral nervous system, Peripheral nervous system); Unit V (Cardiovascular system) 1. Study of compound microscope. 2. Microscopic study of epithelial and connective tissue 3. Microscopic study of muscular and nervous tissue 4. Identification of axial bones 5. Identification of appendicular bones 6. Introduction to hemocytometry. 7. Enumeration of white blood cell (WBC) count 8. Enumeration of total red blood corpuscles (RBC) counts 9. Determination of bleeding time 10. Determination of clotting time 11. Estimation of hemoglobin content 12. Determination of blood group. 13. Determination of erythrocyte sedimentation rate (ESR). 14. Determination of heart rate and pulse rate. 15. Recording of blood pressure.
 

PHARMACEUTICAL ANALYSIS

Unit I(Pharmaceutical analysis, Errors, Pharmacopoeia); Unit II(Acid base titration, Non aqueous titration); Unit III(Precipitation titration, Complexometric titration, Gravimetry, Basic Principles,methods and application of diazotisation titration); Unit IV(Redox titrations); Unit V(Electrochemical methods of analysis- Conductometry, Potentiometry, Polarography) Limit Tests- (1) Chloride (2) Sulphate (3) Iron (4) Arsenic; Preparation and standardization of -(1) Sodium hydroxide (2) Sulphuric acid (3) Sodium thiosulfate (4) Potassium permanganate (5) Ceric ammonium sulphate; Assay of the following compounds along with Standardization of Titrant- (1) Ammonium chloride by acid base titration (2) Ferrous sulphate by Cerimetry (3) Copper sulphate by Iodometry (4) Calcium gluconate by complexometry (5) Hydrogen peroxide by Permanganometry (6) Sodium benzoate by non-aqueous titration (7) Sodium Chloride by precipitation titration; Determination of Normality by electro-analytical methods – (1) Conductometric titration of strong acid against strong base (2) Conductometric titration of strong acid and weak acid against strong base (3) Potentiometric titration of strong acid against strong base
 

PHARMACEUTICS- I

Unit I(Historical background and development of profession of pharmacy, Prescription, Dosage forms, Posology); Unit II(Pharmaceutical calculations, Powders, Liquid dosage forms); Unit III(Monophasic liquids, Biphasic liquids Suspensions, Emulsions); Unit IV(Suppositories, Pharmaceutical incompatibilities); Unit V-Semisolid dosage forms 1. Syrups a) Syrup IP’66 b) Compound syrup of Ferrous Phosphate BPC’68 2. Elixirs a) Piperazine citrate elixir b) Paracetamol pediatric elixir 3.Linctus a) Terpin Hydrate Linctus IP’66 4. Solutions b) Iodine Throat Paint (Mandles Paint) a) Strong solution of ammonium acetate b) Cresol with soap solution c) Lugol’s solution 5. Suspensions a) Calamine lotion b) Magnesium Hydroxide mixture c) Aluminimum Hydroxide gel 6. Emulsions a) Turpentine Liniment b) Liquid paraffin emulsion 7. Powders and Granules a) ORS powder (WHO) b) Effervescent granules c)Dusting powder d)Divded powders 8. Suppositories a) Glycero gelatin suppository b) Coca butter suppository c) Zinc Oxide suppository 8. Semisolids a) Sulphur ointment b) Non staining-iodine ointment with methyl salicylate c) Carbopal gel 9. Gargles and Mouthwashes a) Iodine gargle b) Chlorhexidine mouthwash
 

PHARMACEUTICAL INORGANIC CHEMISTRY

Unit I(Impurities in pharmaceutical substances, General methods of preparation of compounds); Unit II(Acids, Bases and Buffers, Major extra and intracellular electrolytes, Dental products); Unit III(Gastrointestinal agents, Acidifiers, Antacid, Cathartics, Antimicrobials); Unit IV(Miscellaneous compounds, Expectorants,  Emetics, Haematinics, Poison and Antidote, Astringents); Unit V- Radiopharmaceuticals 1.Limit tests for following ions(Chlorides and Sulphates Modified limit test for Chlorides and Sulphates Limit test for Iron Limit test for Heavy metals Limit test for Lead Limit test for Arsenic) 2. Identification test Magnesium hydroxide Ferrous sulphate Sodium bicarbonate Calcium gluconate Copper sulphate 3.Test for purity Swelling power of Bentonite Neutralizing capacity of aluminum hydroxide gel Determination of potassium iodate and iodine in potassium Iodide 4.Preparation of inorganic pharmaceuticals Boric acid Potash alum Ferrous sulphate
 

COMMUNICATION SKILLS

Unit I(Communication Skills, Barriers to communication, Perspectives in Communication); Unit II(Elements of Communication, Communication Styles); Unit III(Basic Listening Skills, Effective Written Communication, Writing Effectively); Unit IV(Interview Skills, Giving Presentations); Unit V- Group Discussion Basic communications covering the following topics -Meeting People Asking Questions Making Friends What did you do? Do’s and Don’ts; Pronunciations covering the following topics- Pronunciation (Consonant Sounds) Pronunciation and Nouns Pronunciation (Vowel Sounds); Advanced Learning Listening Comprehension / Direct and Indirect Speech Figures of Speech Effective Communication Writing Skills Effective Writing Interview Handling Skills E-Mail etiquette Presentation Skills
 

REMEDIALBIOLOGY

Unit I(Living world, Morphology of Flowering plants); Unit II(Body fluids and circulation, Digestion and Absorption, Breathing and respiration); Unit III(Excretory products and their elimination, Neural control and coordination, Chemical coordination and regulation, Human reproduction); Unit IV(Plants and mineral nutrition, Photosynthesis); Unit V(Plant respiration, Plant growth and development, Cell – The unit of life, Tissues 1. Introduction to experiments in biology a) Study of Microscope b) Section cutting techniques c) Mounting and staining d) Permanent slide preparation 2. Study of cell and its inclusions 3. Study of Stem, Root, Leaf, seed, fruit, flower and their modifications 4. Detailed study of frog by using computer models 5. Microscopic study and identification of tissues pertinent to Stem, Root Leaf, seed, fruit and flower 6. Identification of bones 7. Determination of blood group 8. Determination of blood pressure 9. Determination of tidal volume
REMEDIAL MATHEMATICS Unit I(Partial fraction, Logarithms, Function, Limits and continuity); Unit II(Matrices and Determinant); Unit III(Calculus –Differentiation); Unit IV(Analytical Geometry- Introduction, Straight Line, Integration); Unit V(Differential Equations-Application in solving Pharmacokinetic equations, Laplace Transform- Application in solving Chemical kinetics and Pharmacokinetics equations)  

 

B Pharmacy first year Subjects for Semester 2

Subjects Theory Practical
Hours Marks Hours Marks
HUMAN ANATOMY AND PHYSIOLOGY-II 45 100 4/week 50
PHARMACEUTICAL ORGANIC CHEMISTRY-I 45 100 4/week 50
BIOCHEMISTRY 45 100 4/week 50
PATHOPHYSIOLOGY 45 100
COMPUTER APPLICATIONS IN PHARMACY* 30 75 25
ENVIRONMENTAL SCIENCES* 30 75
 
Total marks 725

* The subject experts at college level shall conduct examinations

B Pharma First year Syllabus for Semester 2

Subjects Syllabus
Theory Practical
 

HUMAN ANATOMY AND PHYSIOLOGY-II

Unit I- Nervous system (Organization of nervous system, neuron, neuroglia, classification and properties of nerve fibre, electrophysiology, action potential, nerve impulse, receptors, synapse, neurotransmitters. Central nervous system: Meninges, ventricles of brain and cerebrospinal fluid, structure and functions of brain (cerebrum, brain stem, cerebellum), spinal cord (gross structure, functions of afferent and efferent nerve tracts, reflex activity) ); Unit II- Digestive system (Anatomy of GI Tract with special reference to anatomy and functions of stomach, Acid production in the stomach, regulation of acid production through parasympathetic nervous system, pepsin role in protein digestion) small intestine 54 and large intestine, anatomy and functions of salivary glands, pancreas and liver, movements of GIT, digestion and absorption of nutrients and disorders of GIT.  Energetics-Formation and role of ATP, Creatinine Phosphate and BMR)  ;Unit III- Respiratory system (Anatomy of respiratory system with special reference to anatomy of lungs, mechanism of respiration, regulation of respiration Lung Volumes and capacities transport of respiratory gases, artificial respiration, and resuscitation methods), Urinary system (Anatomy of urinary tract with special reference to anatomy of kidney and nephrons, functions of kidney and urinary tract, physiology of urine formation, micturition reflex and role of kidneys in acid base balance, role of RAS in kidney and disorders of kidney); Unit IV- Endocrine system (Classification of hormones, mechanism of hormone action, structure and functions of pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, pineal gland, thymus and their disorders.); Unit V- Reproductive system (Anatomy of male and female reproductive system, Functions of male and female reproductive system, sex hormones, physiology of menstruation, fertilization, spermatogenesis, oogenesis, pregnancy and parturition), Introduction to genetics Chromosomes, genes and DNA, protein synthesis, genetic pattern of inheritance 1. To study the integumentary and special senses using specimen, models, etc., 2. To study the nervous system using specimen, models, etc., 3. To study the endocrine system using specimen, models, etc 4. To demonstrate the general neurological examination 5. To demonstrate the function of olfactory nerve 6. To examine the different types of taste. 7. To demonstrate the visual acuity 8. To demonstrate the reflex activity 9. Recording of body temperature 10. To demonstrate positive and negative feedback mechanism. 11. Determination of tidal volume and vital capacity. 12. Study of digestive, respiratory, cardiovascular systems, urinary and reproductive systems with the help of models, charts and specimens. 13. Recording of basal mass index. 14. Study of family planning devices and pregnancy diagnosis test. 15. Demonstration of total blood count by cell analyser 16. Permanent slides of vital organs and gonads
 

PHARMACEUTICAL ORGANIC CHEMISTRY –I

Unit I- Classification, nomenclature and isomerism, Classification of Organic Compounds Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds) Structural isomerisms in organic compounds); Unit II- Alkanes*, Alkenes* and Conjugated dienes* (SP3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of alkenes, SP2 hybridization in alkenes E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti Markownikoff’s orientation. Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement); Unit III- Alkyl halides* (SN1 and SN2 reactions – kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions, Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform), Alcohols*( Qualitative tests, Structure and uses of Ethyl alcohol, Methyl alcohol, chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene glycol); Unit IV- Carbonyl compounds* (Aldehydes and ketones) Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde); Unit V- Carboxylic acids* (Acidity of carboxylic acids, effect of substituents on acidity, inductive effect and qualitative tests for carboxylic acids ,amide and ester Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid, Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate, Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid), Aliphatic amines* – Basicity, effect of substituent on Basicity. Qualitative test, Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine) I. Systematic qualitative analysis of unknown organic compounds like

1. Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation and unsaturation, etc. 2. Detection of elements like Nitrogen, Sulphur and Halogen by Lassaigne’s test 3. Solubility test 4. Functional group test like Phenols, Amides/ Urea, Carbohydrates, Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters, Aromatic and Halogenated Hydrocarbons, Nitro compounds and Anilides. 5. Melting point/Boiling point of organic compounds 6. Identification of the unknown compound from the literature using melting point/ boiling point. 7. Preparation of the derivatives and confirmation of the unknown compound by melting point/ boiling point. 8. Minimum 5 unknown organic compounds to be analysed systematically;

II- Preparation of suitable solid derivatives from organic compounds;

III. Construction of molecular models

 

BIOCHEMISTRY

Unit I– Biomolecules (Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins), Bioenergetics (Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential. Energy rich compounds; classification; biological significances of ATP and cyclic AMP) ; Unit II- Carbohydrate metabolism(Glycolysis – Pathway, energetics and significance,Citric acid cycle- Pathway, energetics and significance, HMP shunt and its significance, Glucose-6-Phosphate dehydrogenase (G6PD) deficiency, Glycogen metabolism Pathways and glycogen storage diseases (GSD), Gluconeogenesis- Pathway and its significance, Hormonal regulation of blood glucose level and Diabetes mellitus), Biological oxidation(Electron transport chain (ETC) and its mechanism. Oxidative phosphorylation & its mechanism and substrate phosphorylation, Inhibitors ETC and oxidative phosphorylation/Uncouplers.); Unit III –Lipid metabolism(β-Oxidation of saturated fatty acid (Palmitic acid), Formation and utilization of ketone bodies, ketoacidosis

De novo synthesis of fatty acids (Palmitic acid), Biological significance of cholesterol and conversion of cholesterol into

bile acids, steroid hormone and vitamin D,Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity.) Amino acid metabolism

(General reactions of amino acid metabolism: Transamination,

deamination & decarboxylation, urea cycle and its disorders,

Catabolism of phenylalanine and tyrosine and their metabolic disorders(Phenyketonuria, Albinism, alkeptonuria, tyrosinemia), Synthesis and significance of biological substances; 5-HT, melatonin,

dopamine, noradrenaline, adrenaline, Catabolism of heme; hyperbilirubinemia and jaundi); Unit IV- Nucleic acid metabolism and genetic information transfer

(Biosynthesis of purine and pyrimidine nucleotides,

Pharmacology Text Books Lists

Catabolism of purine nucleotides and Hyperuricemia and Gout disease, Organization of mammalian genome,

Structure of DNA and RNA and their functions, DNA replication (semi conservative model),

Transcription or RNA synthesis

Genetic code, Translation or Protein synthesis and inhibitors); Unit V- Enzymes

(Introduction, properties, nomenclature and IUB classification of enzymes,

Enzyme kinetics (Michaelis plot, Line Weaver Burke plot)

Enzyme inhibitors with examples,

Regulation of enzymes: enzyme induction and repression, allosteric

enzymes regulation, Therapeutic and diagnostic applications of enzymes and isoenzymes, Coenzymes –Structure and biochemical functions)

1. Qualitative analysis of carbohydrates (Glucose, Fructose, Lactose, Maltose,Sucrose and starch)

2. Identification tests for Proteins (albumin and Casein)

3. Quantitative analysis of reducing sugars (DNSA method) and Proteins (Biuret method)

4. Qualitative analysis of urine for abnormal constituents

5. Determination of blood creatinine

6. Determination of blood sugar

7. Determination of serum total cholesterol

8. Preparation of buffer solution and measurement of pH

9. Study of enzymatic hydrolysis of starch

10. Determination of Salivary amylase activity

11. Study the effect of Temperature on Salivary amylase activity

12. Study the effect of substrate concentration on salivary amylase activity.

PATHOPHYSIOLOGY Unit I – Basic principles of Cell injury and Adaptation:

(Introduction, definitions, Homeostasis, Components and Types of Feedback systems,

Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage,

Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes

(Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis, Electrolyte imbalance), Basic mechanism involved in the process of inflammation and repair:

(Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism

of Inflammation – Alteration in vascular permeability and blood flow, migration of

WBC’s, Mediators of inflammation, Basic principles of wound healing in the

skin, Pathophysiology of Atherosclerosis); Unit II Cardiovascular System:

(Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis), Respiratory system: (Asthma, Chronic obstructive airways diseases.), Renal system: (Acute and chronic renal failure.)

Unit III- Haematological Diseases: (Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, haemophilia), Endocrine system: (Diabetes, thyroid diseases, disorders of sex hormones.), Nervous system: (Epilepsy, Parkinson’s disease, stroke, psychiatric disorders:

Depression, schizophrenia and Alzheimer’s disease.), Gastrointestinal system: (Peptic Ulcer),

Unit IVInflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver

Disease, Disease of bones and joints: (Rheumatoid arthritis, osteoporosis and gout), Principles of cancer: (classification, etiology and pathogenesis of cancer), Diseases of bones and joints: (Rheumatoid Arthritis, Osteoporosis, Gout), Principles of Cancer:  (Classification, etiology and pathogenesis of Cancer)

Unit V- Infectious diseases: (Meningitis, Typhoid, Leprosy, Tuberculosis, Urinary tract infections), Sexually transmitted diseases: (AIDS, Syphilis, Gonorrhea)

 

 

When to Write a Pharmacy Progress Note

 

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COMPUTER APPLICATIONS IN PHARMACY Unit IV- Number system: (Binary number system, Decimal number system, Octal

number system, Hexadecimal number systems, conversion decimal to binary, binary to decimal, octal to binary etc, binary addition, binary

subtraction – One’s complement ,Two’s complement method, binary multiplication, binary division.), Concept of Information Systems and Software : (Information gathering, requirement and feasibility analysis, data flow diagrams, process specifications, input/output design, process life cycle, planning and managing the project.); Unit II- Web technologies: (Introduction to HTML, XML,CSS and

Programming languages, introduction to web servers and Server Products, Introduction to databases, MYSQL, MS ACCESS, Pharmacy Drug database.); Unit III- Application of computers in Pharmacy (Drug information storage and

retrieval, Pharmacokinetics, Mathematical model in Drug design, Hospital and Clinical Pharmacy, Electronic Prescribing and discharge (EP) systems, barcode medicine identification and automated dispensing of drugs, mobile technology and adherence monitoring, Diagnostic System, Lab-diagnostic System, Patient Monitoring System, Pharma Information System); Unit IV- Bioinformatics: (Introduction, Objective of Bioinformatics, Bioinformatics Databases, Concept of Bioinformatics, Impact of Bioinformatics in Vaccine Discovery)

Unit-V Computers as data analysis in Preclinical development:

(Chromatographic dada analysis(CDS), Laboratory Information management

System (LIMS) and Text Information Management System(TIMS))

1. Design a questionnaire using a word processing package to gather information about a particular disease.

2. Create a HTML web page to show personal information.

3. Retrieve the information of a drug and its adverse effects using online tools

4 Creating mailing labels Using Label Wizard , generating label in MS WORD

5. Create a database in MS Access to store the patient information with the required fields Using access

6. Design a form in MS Access to view, add, delete and modify the patient record in the database

7. Generating report and printing the report from patient database

8. Creating invoice table using – MS Access

9. Drug information storage and retrieval using MS Access

10. Creating and working with queries in MS Access

11. Exporting Tables, Queries, Forms and Reports to web pages

12. Exporting Tables, Queries, Forms and Reports to XML pages

ENVIRONMENTAL SCIENCES Unit-I:The Multidisciplinary nature of environmental studies

Natural Resources (Renewable and non-renewable resources: Natural resources and associated problems a) Forest resources; b) Water resources; c) Mineral resources; d) Food resources; e) Energy resources; f) Land resources: Role of an individual inconservation of natural resources.); Unit II:   Ecosystems

§ Concept of an ecosystem.

§ Structure and function of an ecosystem.

§ Introduction, types, characteristic features, structure and function of

the ecosystems: Forest ecosystem; Grassland ecosystem; Desert

ecosystem; Aquatic ecosystems (ponds, streams, lakes, rivers, oceans,

estuaries); Unit- III:

Environmental Pollution: Air pollution; Water pollution; Soil pollution.

 

 

 

 

 

 

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 B pharmacy first year syllabus Subjects semister wise PDF

Information related to Bachelor in Pharmacy degree

The fees of B. Pharmacy course is near about 1.5 lacs per semester. B.Pharm students who excel in academics can avail the scholarship in India as well as abroad. There are some scholarship programmes conducted by some universities based on the few criteria. One of them is called as Apex Life Scholarship and it is for Higher Studies in India/Abroad. The amount in India varies between Rs. 500/- to Rs. 3500/- (monthly) whereas Rs. 1 lac to Rs. 5 lacs for abroad studies. Starting from the qualification of H.Sc, SSC, Undergraduates, Postgraduates and students of Professional Courses can apply for the same.

What to do After B. Pharmacy?

To name some private organisations offering scholarships to students for education include Mahalaxmi Education Trust, Bombay, C. Mahindra Education Trust, Sahu Jain Trust, Birla Education Trust, J.N. Tata Endowment and Aga Khan Education Service (India). Also one can consider the option of taking a loan from banks offering education loans. 

List of Pharmaceutical companies in Baddi – Himachal Pradesh – North India

List of Pharmaceutical companies in Baddi - Himachal Pradesh - North India

List of Pharmaceutical companies in Baddi

The country is seeing major development in the pharmaceutical industry in India. Here are List of Pharmaceutical companies in Baddi – Himachal Pradesh – North India. Different states and cities are now moving towards providing lands to pharmaceutical players in their localities or regions to boost “Medical Tourism” in their area. In terms of talking about Baddi, it is a region near solan which offers a perfect destination to companies dealing in processing and manufacturing of pharmaceutical products. It can be now considered as a booming medical industry which is capable of serving best pharmaceutical products and medicines to the north and rest of the country. In terms of talking about the investment, the companies are shelling big money amounts to open their plants and setup manufacturing plants in this region. This region may help in creating their influence among other major pharmacy players exists in the industry. The national and international companies from india as well as world are willing to setup their plant in Baddi. In terms of talking about the peripheries of the region, it features a different kind of peace and satisfaction to the workers working there. The region is yet to flourish in a better way.

List of Pharmaceutical companies in Baddi - Himachal Pradesh - North India

List of Pharmaceutical companies in Baddi

There are various pharmaceutical companies in Baddi which are as follows, you should refer to this lists to get better understanding of companies dealing in pharmacy.

  1. Aarge Formulations
  2. Abott healthcare pvt ltd.
  3. Able Pharma
  4. Magbro Healthcare pvt ltd.
  5. Admac solution
  6. Adley formulations
  7. Atlantic Biotech
  8. Kaizen Pharmaceuticals
  9. Anrose Pharma
  10. Lancer Pharmaceuticals

As Baddi is now growing day by day in terms of flourishing medical industry, the people from another country prefer to come to India to get their best-in class and affordable treatment without any botheration. This will offer them a good chance to get good quality of consultation and doctor to cure the diseases in a better way.

The pharmaceutical companies are setting large scale units and plants to manufacture large number of pharmaceutical products such as medicines, tools etc. The influential region of Baddi helps companies to reach out to more audience to increase their sales profit and margins. The companies are following very effective strategy and expertise policy to earn in a good manner. The earnings in this industry is more influential in terms of providing materials and services.

Computers Questions & Answers M pharm B Pharm – 1 st 2nd Year D B M Pharmacy

Computers Questions & Answers M pharm B Pharm - 1 st 2nd Year D B M Pharmacy

1. Briefly describe the categories of computer networks?

Networks may be classified according to a wide variety of characteristics such as medium used to transport the data, communications protocol used, scale, topology, organizational scope, etc.

A communications protocol defines the formats and rules for exchanging information via a network. Well-known communications protocols are Ethernet, which is a family of protocols used in LANs, the Internet Protocol Suite, which is used not only in the eponymous Internet, but today nearly ubiquitously in any computer network

One way to categorize the different types of computer network designs is by their scope or scale. For historical reasons, the networking industry refers to nearly every type of design as some kind of area network. Common examples of area network types are:

LAN – Local Area Network
WLAN – Wireless Local Area Network
WAN – Wide Area Network
MAN – Metropolitan Area Network
SAN – Storage Area Network, System Area Network, Server Area Network, or sometimes Small Area Network
CAN – Campus Area Network, Controller Area Network, or sometimes Cluster Area Network
PAN – Personal Area Network
DAN – Desk Area Network
LAN and WAN were the original categories of area networks, while the others have gradually emerged over many years of technology evolution.

LAN – Local Area Network
A LAN connects network devices over a relatively short distance. A networked office building, school, or home usually contains a single LAN, though sometimes one building will contain a few small LANs (perhaps one per room), and occasionally a LAN will span a group of nearby buildings. In TCP/IP networking, a LAN is often but not always implemented as a single IP subnet.

In addition to operating in a limited space, LANs are also typically owned, controlled, and managed by a single person or organization. They also tend to use certain connectivity technologies, primarily Ethernet and Token Ring

WAN – Wide Area Network
As the term implies, a WAN spans a large physical distance. The Internet is the largest WAN, spanning the Earth.

A WAN is a geographically-dispersed collection of LANs. A network device called a router connects LANs to a WAN. In IP networking, the router maintains both a LAN address and a WAN address.

A WAN differs from a LAN in several important ways. Most WANs (like the Internet) are not owned by any one organization but rather exist under collective or distributed ownership and management. WANs tend to use technology like ATM, Frame Relay and X.25 for connectivity over the longer distances.

LAN, WAN and Home Networking

Residences typically employ one LAN and connect to the Internet WAN via an Internet Service Provider (ISP) using a broadband modem. The ISP provides a WAN IP address to the modem, and all of the computers on the home network use LAN (so-called private) IP addresses. All computers on the home LAN can communicate directly with each other but must go through a central gateway, typically a broadband router, to reach the ISP.

Other Types of Area Networks

While LAN and WAN are by far the most popular network types mentioned, you may also commonly see references to these others:
Wireless Local Area Network – a LAN based on WiFi wireless network technology
Metropolitan Area Network – a network spanning a physical area larger than a LAN but smaller than a WAN, such as a city. A MAN is typically owned an operated by a single entity such as a government body or large corporation.
Campus Area Network – a network spanning multiple LANs but smaller than a MAN, such as on a university or local business campus.
Storage Area Network – connects servers to data storage devices through a technology like Fibre Channel.
System Area Network – links high-performance computers with high-speed connections in a cluster configuration. Also known as Cluster Area Network.

Virtual private network

A virtual private network (VPN) is a computer network in which some of the links between nodes are carried by open connections or virtual circuits in some larger network (e.g., the Internet) instead of by physical wires. The data link layer protocols of the virtual network are said to be tunneled through the larger network when this is the case. One common application is secure communications through the public Internet, but a VPN need not have explicit security features, such as authentication or content encryption. VPNs, for example, can be used to separate the traffic of different user communities over an underlying network with strong security features.

VPN may have best-effort performance, or may have a defined service level agreement (SLA) between the VPN customer and the VPN service provider. Generally, a VPN has a topology more complex than point-to-point.

Network topology

A network topology is the layout of the interconnections of the nodes of a computer network. Common layouts are:
A bus network: all nodes are connected to a common medium along this medium. This was the layout used in the original Ethernet, called 10BASE5 and 10BASE2.
A star network: all nodes are connected to a special central node. This is the typical layout found in in a Wireless LAN, where each wireless client connects to the central Wireless access point.
A ring network: each node is connected to its left and right neighbor node, such that all nodes are connected and that each node can reach each other node by traversing nodes left- or rightwards. The Fiber Distributed Data Interface (FDDI) made use of such a topology.
A mesh network: each node is connected to an arbitrary number of neighbors in such a way that there is at least one traversal from any node to any other.
A fully connected network: each node is connected to every other node in the network.

Note that the physical layout of the nodes in a network may not necessarily reflect the network topology. As an example, with FDDI, the network topology is a ring (actually two counter-rotating rings), but the physical topology is a star, because all neighboring connections are routed via a central physical location.

2. Describe the basics of conducting a search?

Basic Search Techniques

This tutorial is a how-to guide for creating AND, OR, NOT, phrase, and field searches on Web search engines.

We’ll be using Google as an example. Keep in mind that the illustrated searches will work on most general search engines on the Web.

Tip! Before you read this tutorial, be sure that you understand the basics of Boolean logic. Check out Boolean Searching on the Internet. If you take the time to understand the basics of Boolean logic, you will have a better chance of search success.
Before you search, make a plan!

Putting together a search is a three-step process.

1. Identify your concepts

When planning your search, break down your topic into its separate concepts. Let’s say you’re interested in the effects of global warming on crops. In this case, you have two concepts: GLOBAL WARMING and CROPS.

2. Make a list of search terms for each concept

Once you have identified your concepts, list the terms which describe each concept. Some concepts may have only one term, while others may have many.

global warming
greenhouse effect
greenhouse gases
climate change

crops
crop yields
crop production
food supply

These lists are a suggestion. Depending on the focus of your search, there may be other terms more suited to what you’re looking for.

3. Specify the logical relationships among your search terms

Once you know the words you want to search, you need to establish the logical relationships among them using Boolean logic: AND, OR, NOT.

To keep things simple, you don’t need to use all the words you’ve compiled in a single search. The words are there to help you experiment with different searches until you find the results you want.

Phrase Search

Some words naturally appear in the context of a phrase, for example, freedom of the press. To search on phrases in most search engines, simply enclose the phrase within quotes: “freedom of the press”.

Phrases are especially important when there are stop words in your search. These are “little” words such as a, and, the, in, it, etc. Most search engines tend to ignore these words. If you want to be sure they are included in your search results, enclose them with the rest of your search within quotation marks. You can also put a plus sign (+) in front of them. Yahoo! suggests a combination of quotation marks and the plus sign, e.g., “+in thing”.
Field Search

Field searching is an optional way to focus your search results. With general search engines, you’re searching the full text of many millions of pages, and field searching can help you retrieve results that may be more manageable. For example, you can search for words that appear within a particular Web site, within the URL (Web address), in the page title, and so on. The exact technique for doing this can differ among search engines, so be sure to check out the Help pages before proceeding. Let’s consider a couple of examples on Google.
Title field

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A title search can bring you more relevant results than merely searching for words that appear anywhere on the Web page. It’s more likely that a document that contains your search words in the title will be more relevant that a document that does not. For this reason, many search engines use title words as an important way of ranking search results in order of their relevancy.

Let’s look for Web pages that contain our search terms in the page title. Again, we’ll use Google to try this out, revisiting its advanced search page. Here, you need to open up the page to display all its options by clicking on the plus sign (+) near the bottom of the page next to the options for Date, usage rights, numeric range, and more.

Where your keywords show up gives you the option to select in the title of the page. Let’s search for hurricane caribbean deaths.

Notice that Google translated this search into allintitle: hurricane caribbean deaths. If you memorize this search syntax, you can conduct this search from Google’s main search page.

Site field

Searching on the site field is another useful way of finding relevant results. In this case, you search on the top-level and second-level domain names together, and then use AND logic to add topical words to your search.

You can read about domain structures in the tutorial A Basic Guide to the World Wide Web. Briefly, to take an example shown below: “nasa” is a second-level domain, and “gov” is a top-level domain.

Examples of sites:

nasa.gov
mit.edu
microsoft.com

Let’s look at an example of a site search. Let’s say you are searching for information about spacewalks conducted by NASA. Try this: spacewalks site:nasa.gov. This search will limit your results to pages on the NASA Web site.

Try this search yourself! You should get results that are similar to the ones shown in the screenshot below.

Notice that all the results come from the site nasa.gov. You can also go to the advanced search page on Google to conduct this search.

Natural language search

A few search engines encourage you to type your search as a “normal” question or sentence, rather than concern yourself with Boolean logic. This is sometimes known as a natural language search. On these engines, a variety of sophisticated techniques are working behind the scenes to analyze your search and return relevant results. Hakia is a good example of this type of engine. Give it a try and see what you think.

3.Define HTML? What does a basic HTML document contain?

HTML, which stands for HyperText Markup Language, is the predominant markup language for web pages. HTML is the basic building-blocks of webpages.
HTML is written in the form of HTML elements consisting of tags, enclosed in angle brackets (like <html>), within the web page content. HTML tags normally come in pairs like <h1> and </h1>. The first tag in a pair is the start tag, the second tag is the end tag (they are also called opening tags and closing tags). In between these tags web designers can add text, tables, images, etc.
The purpose of a web browser is to read HTML documents and compose them into visual or audible web pages. The browser does not display the HTML tags, but uses the tags to interpret the content of the page.
HTML elements form the building blocks of all websites. HTML allows images and objects to be embedded and can be used to create interactive forms.

Creating Your HTML Document

An HTML document contains two distinct parts, the head and the body. The head contains information about the document that is not displayed on the screen. The body then contains everything else that is displayed as part of the web page.

The basic structure then of any HTML page is:
<!DOCTYPE HTML PUBLIC “-//W3C//DTD HTML 3.2//EN”>
<html>
<head>
<!– header info used to contain extra information about
this document, not displayed on the page –>
</head>

<body>

<!– all the HTML for display –>
: :
: :
: :
</body>
</html>

4. Why do people go in for web site? Build a web site of your choice following the elements of a good web site?

If you are looking to promote your business to a lot of people nationally and internationally than website advertising is one of the best ways to do it. Every business in the world needs some kind of marketing strategy that can help the business owner to display his products and services to more and more people so that they are aware of it and that they feel that they need that product or service. In the earlier times, the world of advertisement was very much limited to radio and television that would cost a lot of money to the business owners because they had to get in touch with ad makers who would than come up with innovative ideas to make an ad.
However, things have changed considerably after the advent of Internet. The trend of Internet advertising has caught the attention of millions of business people all over the world because with the help of this technology you can reach billions of people and promote your business, product or services in affordable prices You can take a look at the rate at which websites are being developed which clearly indicates that people today are more interested in marketing their products through the medium of Internet rather than using old traditional methods of marketing.

5. What does a web server do? How does it work? How do you choose a web server platform?

web server can mean two things – a computer on which a web site is hosted and a program that runs on such a computer. So the term web server refers to both hardware and software. We’ll look at each of these individually.
The web server computer – the hardware

A web site is a collection of web pages which are digital files, typically written using HyperText Markup Language (HTML). For a web site to be available to everyone in the world at all times, it need to be stored or “hosted” on a computer that is connected to the internet 27/7/365. Such a computer is known as a Web Server (note the first letter is in uppercase).

You can potentially host a web site on your home computer but this involves a lot of work and constant monitoring. It is easier to “buy” web hosting from a company because there are thousands that offer this service.

There are several requirements for a Server computer – it needs to be fast, have a large storage capacity hard disk and lots of RAM. But the most important is having a permanent internet address also known as an I.P. (Internet protocol) address. If the I.P. address changes, the web site would not be found and will appear offline – the browser will display a cannot find web site error. For details, read differences between your home computer and a web Server.

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The web server program – the software

A web server program is software that runs on the web site hosting Server computer. Its main purpose is to serve web pages; which means it waits for requests from web browsers (also known as clients) and responds by sending the required data back. This client-server interaction is the hallmark of the web!

There are many web server programs available- check list of web servers. The most famous and popular of all web servers is Apache developed by the Apache Foundation. Not only is Apache free but it’s also available for several operating systems including Windows, Macintosh and Linux/Unix.

FYI, differentiating the server program (software) and the Server computer (hardware) by the case of the first letter is suggested and followed only by purists – it is not a rule. Generally, readers quickly understand from the context whether one is referring to the hardware or the software.
What is the role of web server on the Internet?

Web servers – the computer or the program – have a vital role on the Internet. The Server machine hosts (stores) the web site on its hard disk while the server program helps deliver the web pages and their associated files like images and flash movies.

The process of loading a web site/page in a web browser starts with the user either entering the URL in the address bar or clicking on a link. You should know that each web page has a unique address (or URL) on the internet; which means the same page cannot exist in two places. (If a copy does exist in another location, its address would be different from that of the original).

The browser now needs to send out a request for the web page. Behind the scenes, the URL of the requested web page is resolved into an I.P. address, which, in English, means, converted to an I.P. address – something that computers understand. The I.P. address points to the location of the web site host and the request is forwarded to Server computer and passed on to the server software.

The server software now takes up and hunts for the requested web page on the hard disk. On finding the file, it sends a response and the web page file to the browser which then starts displaying the page. A typical web page not only has text but also embedded multimedia elements like images and Flash animation.

These “extra” files are separate from the actual web page and need to be sent one by one for the browser to display the web page correctly. Note (and an important one), ONLY the web browser determines how a web page is displayed; the web server has no control over this. The job of a web server ends once it processes the request from a browser and sends the required information.

Though the request-and-response process might seem to take time especially when you consider that the client and server computers might be thousands of miles apart, it actually happens very fast. That’s because of the HyperText Transfer Protocol (HTTP) which is a set of rules developed by the “big lads” to facilitate the transfer of data over the internet.
.

Every website needs a reliable web server to be hosted on, so that it can be accessed via internet users. Today, in web hosting market there are many types of web servers available running on different platform to select. types are There is a wide range of web servers running on different platform to choose from within the web hosting market today. As per the Netcraft, a company that keeps statistics on the leading web servers and the platforms on the Internet, the most popular platforms and web servers are:

• UNIX and Linux running Apache web server
• Window NT/2000 running Internet Information Server (IIS)
The other web server includes WebLogic, iPlanet, Sun ONE, Zeus and etc… Given the widespread popularity of Apache (closed to 60% market share) and Microsoft IIS (approximately 30%), you can almost guarantee you can find these two platforms are supported by most of the web hosting providers.
Operating systems are an importance piece of software that is required by each computer to be installed before it can function properly. Today, most of the personal computers are running on Microsoft Windows operating system: Win98, WinXP or Win2000.
Likewise, all web servers need operating system to perform different functionalities and different web servers run on different operating systems (or so called platforms). One of the most commonly found platform is UNIX that comes in various varieties that are popular with web hosts, including FreeBSD, NetBSD, OpenBSD and Linux. Another popular platform that has gained strong ground as a platform for web hosting market is Microsoft Windows 2000 and Windows Server 2003.
How do you choose your web server platform?
If your website is purely make up of static web pages (i.e. HTML files), then any web hosting platform will work fine for you. However, if your website allows dynamic content, you will most likely need to run specific server-side functionality such as CGI scripts, JSP, ASP, SSI or PHP. In this case, UNIX platform web hosting will be ideal for your requirement.
On the other hand, if you need to use specific applications that require Windows to run such as ASP, .Net, MS Access, Microsoft SQL server or Cold Fusion, then you will need to find a web hosting providers that support Microsoft’s Windows NT platform. Otherwise, all other server-side functionalities such as PHP, Perl and MySQL can be supported by UNIX platform.
While common programs such as Perl, PHP, Flash etc run on both UNIX and Window platform. Many other free open source software programs are available only for UNIX than for Windows. As a result, UNIX hosting is less expensive than Window hosting. So, if hosting cost is a big concern to you, then you should consider UNIX or Linux hosting.
If you have already decided on the type of design on your web pages, make sure you can find a web hosting plan that support your needs by reading the full features of the web hosting plan before you sign-up.

6.“The potential of world wide web (WWW) on the internet has led to an explosion in commercial activity”. Discuss.

As a commercial medium, the Web offers a number of important benefits which can be examined at both the customer and firm levels. In this way, we can address both demand and supply issues. We discuss the buyer benefits first, followed by the firm benefits. Buyer benefits arise primarily from the structural characteristics of the medium and include availability of information, provision of search mechanisms, and online product trial all of which can lead to reduced uncertainty in the purchase decision. Firm benefits arise from the potential of the Web as a distribution channel, a medium for marketing communications, and a market in and of itself. These efficiencies are associated with Web technology and the interactive nature of the medium.
1.1Consumer Benefits
One important consumer benefit associated with marketing on the Web is the access to greater amounts of dynamic information to support queries for consumer decision making. Hence marketing communications on the Web are more consumer-driven than those provided by traditional media.
In addition to the above, the advantages for industrial consumers are reduced costs to buyers from increased competition in procurement as more suppliers are able to compete in an electronically open marketplace. This increase in competition leads to better quality and variety of goods through expanded markets and the ability to produce customized goods (IITA 1994).

1.2. Benefits to the Firm

Distribution

Firm benefits arise partly from the use of the Web as a distribution channel. First, the Web potentially offers certain classes of providers participation in a market in which distribution costs or cost- of-sales shrink to zero. This is most likely for firms in publishing, information services or digital product categories (Jones 1995). For example, digital products can be delivered immediately, hence such businesses may encounter massive disintermediation or even the eventual elimination of middleman (Michalski 1995). Moreover buyers and sellers can access and contact each other directly, potentially elmininating some of the marketing cost and constraints imposed by such interactions in the terrestial world. This may also have the effect of shrinking the channel and making distribution much more efficient (mainly due to reduced overhead costs through such outcomes as uniformity, automation, and large-scale integration of management processes). Time to complete business transactions may be reduced as well, translating into additional efficiencies for the firm. However, such potential efficiencies must be tempered with market realities (Kline 1995).
Second, business on the Web transfers more of the selling function to the customer, through online ordering and the use of fill-out-forms (Michalski 1995) thus helping to bring transactions to a conclusion. This permits a third benefit in the form of capture of customer information. The technology offers the firm the opportunity to gather market intelligence and monitor consumer choices through customers’ revealed preferences in navigational and purchasing behavior in the Web. Note however that there are many social, legal and technological issues and drawbacks at the present level of technology which prevent the full capitalization of this benefit (see, for example, Caruso 1995).
Marketing Communications

At the present time, most firms use the Web primarily to deliver information about the firm and its offerings and for both internal and external communication (Magid 1995, Sharples 1995) with other firms and consumers. The interactive nature of the medium (see Hoffman & Novak 1995 for discussion) offers another category of firm benefits since it is especially conducive to developing customer relationships. This potential for customer interaction, which is largely asynchronous under current implementations, facilitates relationship marketing and customer support (Cuneo 1995) to a greater degree than ever before possible with traditional media.

Web sites are available on demand to consumers 24 hours a day. The interactive nature of the medium can be used by marketers to hold the attention of the consumer by engaging the consumer in an asynchronous “dialogue” that occurs at both parties’ convenience. This capability of the medium offers unprecedented opportunities to tailor communications precisely to individual customers, allowing individual consumers to request as much information as each desires. Further, it allows the marketer to obtain relevant information from customers for the purposes of serving them more effectively in the future.

The simplest implementations involve engaging customers through the use of email buttons located strategically on the site. More sophisticated implementations may involve fill-out- forms and other incentives designed to engage customers in ongoing relationships with the firm. The objective of such continuous relationship-building is dual-pronged: to give consumers information about the firm and its offering and to receive information from consumers about their needs with respect to such offerings. Hence, effective customized advertising, promotion and customer service (Berniker 1995) is the fifth benefit that the commercial Web offers to the firm.

Operational Benefits

Operational benefits of Web use for industrial sellers are reduced errors, time, and overhead costs in information processing; reduced costs to suppliers by electronically accessing on-line databases of bid opportunities, online abilities to submit bids, and online review of awards.

7. Discuss the uses of Internet activity?

Americans spend nearly a quarter of their time online on social networking sites and blogs, up from 15.8 percent just a year ago (43 percent increase) according to new research released today from The Nielsen Company. The research revealed that Americans spend a third their online time (36 percent) communicating and networking across social networks, blogs, personal email and instant messaging.
Top 10 Sectors by Share of U.S. Internet Time
1 Social Networks
2 Online Games
3 E-mail
4 Portals
5 Instant Messaging
6 Videos/Movies
7 Search
8 Software Manufacturers
9 Multi-category Entertainment
10 Classifieds/Auctions

Internet has become a part of our everyday life. From being used in defense purposes by the United States military for communication initially, to being used worldwide for hundreds of thousands of different purposes, internet has come a long way. Internet is there to stay with us and has taken a place where it is a part of our every day life now.

There are millions of applications of internet. We are in fact as dependent on internet as we are on other utility things like electricity, water etc. In fact many people would think that a part of their life is missing if they are not able to log on for even one day.

Before a few years, people used to get up in the morning and read the newspaper or watch television. Now most people log onto the internet first thing in the morning. So when internet has become so essential in our daily life, what are the things that can be done on the internet and what are it’s many uses?

The following are a list of some of the major uses of the internet :

1. Search engine :
It can be used to search anything and everything. Most popular search engines are google and yahoo searches.

2. Shopping:
Shopping has become easier with the advent of internet. You can buy or sell online.

3. Communication :
This is a major role of the internet. It helps people to communicate either with the use of social networking websites or through e mails. Even chatting is a major use of the internet.

4. Job search:
Nowadays, many people search for their jobs online as it is quicker and there is a larger variety of job vacancies present.

5. Hobbies:
Those who are having certain hobbies can try to improve on it by reading up on many aspects of their hobby.

6. Research: Research papers are present online which helps in the researcher doing a literature review.

7. Studying:
Now right from kinder garden children are exposed to internet and computers. They find many useful things to learn on the internet(though with supervision). Upto doctorate level education, people rely on internet for their education. Online educational books have even reduced the need for a library.

These are only some of the uses of the internet. There are so many more that will can be listed forever. There are also negative aspects of the internet. But the onus is on the user to make use of the internet for it’s benefits and leave all the negative aspects.

Advantages of internet :-

There many advantages to using the internet such as:
Email.
E-mail is an online correspondence system. With e-mail you can send and receive instant electronic messages, which works like writing letters. Your messages are delivered instantly to people anywhere in the world, unlike traditional mail that takes a lot of time. Email is now an essential communication tools in business. It is also excellent for keeping in touch with family and friends. The advantages to email is that it is free ( no charge per use) when compared to telephone, fax and postal services.

Information.
The Internet is a virtual treasure trove of information. Any kind of information on any topic under the sun is available on the Internet. The ‘search engines’ on the Internet can help you to find data on any subject that you need.
There is a huge amount of information available on the internet for just about every subject known to man, ranging from government law and services, trade fairs and conferences, market information, new ideas and technical support.

Services.
Many services are now provided on the internet such as online banking, job seeking and applications, and hotel reservations. Often these services are not available off-line or cost more.

Buy or sell products

The internet is a very effective way to buy and sell products all over the world. Along with getting information on the Internet, you can also shop online. There are many online stores and sites that can be used to look for products as well as buy them using your credit card. You do not need to leave your house and can do all your shopping from the convenience of your home.

Communities.

Communities of all types have sprung up on the internet. Its a great way to meet up with people of similar interest and discuss common issues.

Online Chat:
There are many ‘chat rooms’ on the web that can be accessed to meet new people, make new friends, as well as to stay in touch with old friends.

Downloading Software:
This is one of the most happening and fun things to do via the Internet. You can download innumerable, games, music, videos, movies, and a host of other entertainment software from the Internet, most of which are free.

8. How is internet used by legal practitioners?

The use of the Internet and its component part, the World Wide Web, has grown tremendously in recent years.

Lawyers and others seeking legal information have not been left out in the cold in terms of legal information available on the Internet. Currently available for free are court cases, statutes, regulations, publications, and decisions and orders.

Materials are available not only from federal government sources, but also from state and local sources. This article will look at legal resources on the Internet, how to find them, and what to look for when you do find them.

There are a number of ways to locate legal information on the Internet. One is to use columns or articles in traditional publications. Another is to search the Internet using Web sites established for this purpose, called “search engines.” Lawyers also can refer to the myriad Web sites with lists of legal resources available (resource listings that allow you to click and be taken to another site are called “links”) to find resources of interest.

Searching the Internet. Legal information on the Internet can be found either using “general” or “generic” search engines, or using law- and legal-specific resources. When using generic search engines, searches are best conducted using general descriptive terms such as “computer law” or “employment law” to find Web sites that contain information related to a specific legal topic.

Unless a case or legal concept is extremely well known, searching generic search engines using specific legal terms may not work well (returning no links or returning so many as not to be useful).

Searching generic search engines for specific resources such as the U.S. Supreme Court or the New York State Assembly probably will provide good results. While utilizing generic search engines may help get to general area concepts and sites, using the more specific legal search engines likely will provide more efficient results when searching for specific legal information.

Information and help on searching can be found at “The Spider’s Apprentice” http://www.monash.com/spidap.html. (Because the World Wide Web often is called just “the Web,” allusions to “spiders” that “crawl around” the Web are common). The State University at Albany also maintains a site dedicated to search engines, including descriptions of the various search engines and the data they contain at http://www.albany.edu/library/internet/engines.html.

Using listings and directories.

Many of the generic and legal-specific search engines also contain indices or directories of information organized by topic. Add to these the plethora of sites that list only legal resources–without the ability to undertake the Web-wide database searches offered by the search engines– and the searching attorney should find more than adequate direction in undertaking legal research on the Internet. Attorneys often find a specific legal site that works best for them, and “bookmark” or choose such site as a “favorite” to start from when conducting legal research.

Other resources on the Web.

In addition to search engines, links and directories, there is a tremendous wealth of organizational and secondary material on the Internet. Legal news can be found, often from “name brand” publications updated daily (or even more frequently). Bar associations, often with resources and link pages of their own, also are on the Web, offering member services and information designed to assist their lawyer membership.

A note of caution about using secondary sources is that the Web does not discriminate based on content, quality or accuracy of information. Anyone with a Web account, appropriate software and a little bit of knowledge, can have a Web page. Before relying upon something you have found on the Web other than primary authority obtained from a verified source, read it extremely critically.

There are reported occasions where non-lawyers have put up legal sites (often related to litigation they themselves have gone through) with inaccurate information. Even reputable sources such as daily legal news producers have included articles with inaccurate information.

One legal news site recently included an article on attorney-client privilege and e-mail and stated that New York had considered–but not adopted–a change in the law to protect such communications. In fact, New York did adopt that law in 1998, and after notification the article has been changed to reflect the true state of the law.

Because Web publishing is not subject to the same requirements as print publications, often even skimping in the area of editing and review of content, attorneys need to be careful not to rely too heavily on information found at “unofficial” or secondary sites.

In using cases and statutes, make certain to get the text from an approved or official site. If using secondary materials from a publication that is otherwise in print (such as a law review), this concern is diminished.

9.Define networking? Highlight the issues of network security?

A computer network, often simply referred to as a network, is a collection of computers and devices interconnected by communications channels that facilitate communications and allows sharing of resources and information among interconnected devices. Put more simply, a computer network is a collection of two or more computers linked together for the purposes of sharing information, resources, among other things. Computer networking or Data Communications (Datacom) is the engineering discipline concerned with computer networks. Computer networking is sometimes considered a sub-discipline of electrical engineering, telecommunications, computer science, information technology and/or computer engineering since it relies heavily upon the theoretical and practical application of these scientific and engineering disciplines
Businesses are using networking for communication with clients and employees and Make a productive, innovative, shared work environment. So sometimes they ignore many security issues to get the network up and running. The following are a few common network security issues which are ignored by the owner.
1. Improper/weak passwords. The Password is simplest form of security. By leaving passwords easy(i.e., password/admin/your name/mobile no. or city ), unauthorized Hackers are practically invited to view Important data. Passwords are more secure when they contain both letters and numbers in a combination of upper-case and lower-case characters, special character and they should be changed periodically.
2. Lack of education. Educated users in the use of their Services, especially with regard to e-mail, attachments, and downloads. They need to know exactly what kinds of threats are out there. Uneducated computer users are often those who fall victim to malware’s, spywares, keyloggers, viruses, and phishing attacks, all of which are designed to Harm the systems or leak personal details like passwords, login details to a third party without the user’s permission.
3. No backups. Idleness is one of the biggest security threats. It’s considerably more difficult to completely re-create a crippled system than it is to take the time to take proper backups of your data. Create backups often, and do not immediately overwrite or delete them with the next set of backups. In advance, make copies of backup’s and keep them off-site in case of emergency.
4. Plug and surf. Unfortunately, computers are not designed to be connected to the Internet straight out of the box. Before a phone line, Ethernet cable, or wireless Device is anywhere near a new computer, install a line of Protection software. So this should include Protection from viruses, multiple spyware scanners, and a program that runs in the background to prevent malicious software from ever being installed.
5. Not updating. What good are all those virus and spyware scanners if they’re not updated? It’s very important to update what are called the “virus/spyware databases” every week. This keeps the scanners up-to-date to detect the latest Viruses and malicious software’s.
6. Ignoring security patches. Security holes may exist in your so perating System. No software is perfect. Once an vulnerability or hole is found, it’s usually exploited within a very short period of time. Therefore, it is imperative to install security patches as soon as possible in your system.
7. Trust. Ads on the Internet have become tortuous and illusive. They now appear as “urgent system error messages” and warnings designed to scare users into clicking. As a rule of thumb, if a popup window contains an ad claiming to end popups, chances are it’s a scam.
8. Not using encryption. Encryption is very important when dealing with online banking and credit cards payments. Storing and transferring unencrypted data is the equivalent of posting that data for everyone to see. If you’re not comfortable implementing encryption technology, have an IT specialist assist you.
9. Trying to do it all yourself. Setting up a network, applying proper security measures, and downloading and installing software can be tricky. Large companies have IT departments. Small business owners should also ask for advice or even hire help. It’s worth the extra cost.
10. Proper instruction. Security measures are most effective if everyone is aware of how the system works. Give employees a brief overview of the security measures they’re expected to follow.
So these are a few common network security issues which should not ignore by a good business owner

10.“Security is a term with both a business meaning and a technical meaning”. Discuss the statement in terms of security basics?

10. “Security is a term with both a business meaning and a technical meaning”. Discuss the statement in terms of security basics?

Security Management for networks is different for all kinds of situations. A home or small office would only require basic security while large businesses will require high maintenance and advanced software and hardware to prevent malicious attacks from hacking and spamming.
Homes & Small Businesses
• A basic firewall or a unified threat management system.
• For Windows users, basic Antivirus software. An anti-spyware program would also be a good idea. There are many other types of antivirus or anti-spyware programs out there to be considered.
• When using a wireless connection, use a robust password. Also try to use the strongest security supported by your wireless devices, such as WPA2 with AES encryption.
• If using Wireless: Change the default SSID network name, also disable SSID Broadcast; as this function is unnecessary for home use. (However, many security experts consider this to be relatively useless. http://blogs.zdnet.com/Ou/index.php?p=43 )
• Enable MAC Address filtering to keep track of all home network MAC devices connecting to your router.
• Assign STATIC IP addresses to network devices.
• Disable ICMP ping on router.
• Review router or firewall logs to help identify abnormal network connections or traffic to the Internet.
• Use passwords for all accounts.
• Have multiple accounts per family member, using non-administrative accounts for day-to-day activities. Disable the guest account (Control Panel> Administrative Tools> Computer Management> Users).
• Raise awareness about information security to children.[5]
Medium businesses
• A fairly strong firewall or Unified Threat Management System
• Strong Antivirus software and Internet Security Software.
• For authentication, use strong passwords and change it on a bi-weekly/monthly basis.
• When using a wireless connection, use a robust password.
• Raise awareness about physical security to employees.
• Use an optional network analyzer or network monitor.
• An enlightened administrator or manager.
Large businesses
• A strong firewall and proxy to keep unwanted people out.
• A strong Antivirus software package and Internet Security Software package.
• For authentication, use strong passwords and change it on a weekly/bi-weekly basis.
• When using a wireless connection, use a robust password.
• Exercise physical security precautions to employees.
• Prepare a network analyzer or network monitor and use it when needed.
• Implement physical security management like closed circuit television for entry areas and restricted zones.
• Security fencing to mark the company’s perimeter.
• Fire extinguishers for fire-sensitive areas like server rooms and security rooms.
• Security guards can help to maximize security.

# List of Pharmaceutical companies in Ahmedabad – Gujarat- Address – PDF – Top 10 =50 = 100

list-of-pharmaceutical-companies-in-ahmedabad-gujarat-address-pdf-top-10-50-100

Here is the List of Pharmaceutical companies in Ahmedabad. You can see the top 10 best pharma companies manufacturing processing companies in this list

# List of Pharmaceutical companies in Ahmedabad

The Pharmaceutical is considered as an essential economic sector in India’s growth and development. As medical and Pharma industry is booming, there are lot of economic regions which are opting to open pharmaceutical plans. One such city is Ahmedabad which is inviting Pharma based companies to start their business and manufacturing in Ahmedabad. Due to the growing needs of the medical industry, pharmacy is now considered as a sector with fast pace growth. Due to opening of businesses and manufacturing units, large numbers of people are becoming employable in these units.

There are lot of companies who has already established their network in the city of Ahmedabad. They have also prepared a farsighted vision to combat with other states and other players in the market. This article features a comprehensive list of Pharmaceutical companies in Ahmedabad.

list-of-pharmaceutical-companies-in-ahmedabad-gujarat-address-pdf-top-10-50-100

In terms of talking about pharmaceutical companies, these companies are considered very essential in medical and pharmacy sector as they care of complete manufacturing and processing of important drugs and medicines. Apart from this, they are also responsible for supply of medicines to important hospitals and medical centres.

Top 10 List of Pharmaceutical Companies in Ahmedabad Gujarat

  1. Reputed Micro Systems
  2. Dirghayu healthcare
  3. Yash pharma mechinaries
  4. Veeda clinical research
  5. Synchron research services pvt. Ltd.
  6. Shradha Exports
  7. Relish Pharmaceutical Limited.
  8. Nuclius Life Sciences Pvt. Ltd.
  9. Minal Intermediates
  10. Acron Pharmaceuticals

Best Pharmaceutical companies in Ahmedabad 

These pharmaceutical companies are also helping states to develop their medical ecosystem in much better way. It helps hospitals and medical research center to get the medicines in low cost as they have been manufactured and processed around the boundaries of their city. This is the very crucial reason how medical industry is flourishing in a fast-pace manner. Apart from establishing companies and industry to raise the industry of medical industry, this can also be proved as an effective way to provide employability to medical and pharmacy students across the region and state. These companies hire candidates in very large number so that they can assist and play important part in manufacturing, processing and distributing drugs and medicines to different hospitals. This will give a better future prospect to the students to opt for medical or pharmacy stream.

I hope this article has helped you in terms of finding best pharmaceutical companies that are in existence and operating since long time in Ahmedabad Gujarat. This will help you to get better understanding of prospects in industry.